hostpathogen interactions in urinary tract infection
Management of suspected bacterial urinary tract infection in adults pdf
Ngày tải lên :
08/03/2014, 14:20
... upper urinary
tract infection. The presence of symptomatic bacteriuria can be established with
a single urine sample.
upper urinary tract
infection (UUTI)
evidence of urinary tract infection ... lower
urinary tract abnormalities (mainly involving bladder outflow obstruction) in 80% of adult males presenting
with simple or recurrent urinary tract infections, but without prior urinary ... symptoms such
as dysuria, urgency or frequency (suggesting lower urinary tract infection) or loin pain (suggesting upper
urinary tract infection) are extremely likely to have bacteriuria (see...
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Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"
Ngày tải lên :
25/10/2012, 10:02
... Circulating levels of copeptin, a
novel biomarker, in lower respiratory tract infections. Eur J Clin Invest
2007, 37:145-152.
22. Christ-Crain M, Muller B: Biomarkers in respiratory tract infections: ... Nicolas-Chanoin MH,
Wolff M, Spencer RC, Hemmer M: The prevalence of nosocomial
infection in intensive care units in Europe. Results of the European
Prevalence of Infection in Intensive Care ... ET-1:
Endothelin-1; ICU: intensive care unit; IDSA: Infectious Disease Society of Amer-
ica; IQR: interquartile range; LRTI: lower respiratory tract infection; PCT: procalci-
tonin; PIRO: predisposition: insult /infection: ...
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Báo cáo y học: "Pathogenic organisms in hip joint infections"
Ngày tải lên :
26/10/2012, 09:57
... of quinolones,
aminoglycosides, and tetracyclines. In principle, the
spectrum of available antibiotics is limited by the
specific pharmacokinetic requirements in the treat-
ment of joint infections. ... starting point
of a progressive infection spreading in continuity,
lymphogenic or haematogenic. In general, the detec-
tion and treatment of acute infectious arthritis is an
acute emerging ... a
large number of different binding molecules. Espe-
cially fibrinogen, extracellular matrix proteins and
glycosaminoglycans, including fibronectin and
laminin, are components of the blood...
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Tài liệu Báo cáo khoa học: Transient RNA–protein interactions in RNA folding docx
Ngày tải lên :
14/02/2014, 19:20
... blocking or presenting of
binding sites for the ribosome [4]. These are just a few
Keywords
mode of binding; proteins that promote
RNA folding; RNA chaperones; RNA folding
problem; transient interactions
Correspondence
B. ... changes in the RNA are
introduced during the transient interaction arises. Ini-
tial results indicate that the protein acts as an electro-
static lubricant that shields repulsive interactions
within ... helicases. The binding sites for double-
stranded RNA and ATP overlap, resulting in coupled
binding of both molecules. Simultaneous binding
forces the RNA into a bent conformation that is
incompatible...
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Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase–methionine synthase reductase complex docx
Ngày tải lên :
18/02/2014, 08:20
... structure of the cobalamin-binding domain
Homocysteine
Methionine
Co
Methylcob(III)alamin
Cob(I)alamin
Primary
turnover
cycle
H
CH
3
H
4
folate
AdoHyc
Cob(I)alamin
Cob(II)alamin
H
4
folate
Co
NADPH
A
doMet
e
–
FAD
FMN
NADPH
NADP
+
e
–
Reactivation
Co
Fig. ... 53–56.
34 Tollin G (1995) Use of flavin photochemistry to probe
intraprotein and interprotein electron transfer mecha-
nisms. J Bioenerg Biomembr 27, 303–309.
Supporting information
The following supplementary ... CH
3
-H
4
-folate binding-domain (black barrel) form discrete complexes with the cobalamin-binding domain (dark grey circle).
hMS is inactivated approximately every 200–1000 catalytic turnovers [owing to...
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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
Ngày tải lên :
19/02/2014, 06:20
... strong, neutralizing action of the cytosolic RNase
inhibitor (cRI), a 50-kDa protein containing 16 leu-
cine-rich repeat motifs [7,8]. In fact, onconase from
Rana pipiens eggs [9], and seminal RNase ... proteins, with high
isoelectric point values. Thus we investigated the effects
Table 1. Natural and engineered RNases investigated in this study. IC
50
is the RNase concentration producing half-maximal ... homologous to the RNases investigated in
this study, have been isolated from human eosinophils,
namely eosinophil-derived neurotoxin (EDN) and eosi-
nophil cationic protein (ECP). They are RNases...
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Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis docx
Ngày tải lên :
06/03/2014, 04:20
... Gerstoft J, Pedersen C. Pharmacokinetic
interaction between rifampin and the combination of indinavir and low-dose ritonavir in HIV-
infected patients.
Clin Infect Dis.
Feb 1 2004;38(3):426-429.
26. ... together
Delavirdine AUC
by 95%
Etravirine
Etravirine and rifampin should not be used together
Marked decrease in etravirine predicted, based on data on the
interaction with rifabutin
Single protease inhibitors
Recommended ... Increasing nevirapine dose can
overcome reduced bioavailability due to rifampicin coadministration.
J Acquir Immune Defi c Syndr.
May 2006;42(1):36-41.
6
Predicting Drug Interactions Involving...
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Respiratory tract infections – antibiotic prescribing doc
Ngày tải lên :
07/03/2014, 13:20
... antibiotic prescribing
Prescribing of antibiotics for
self-limiting respiratory tract
infections in adults and children
in primary care
NICE clinical guideline 69 – respiratory tract infections ... guideline 69 – respiratory tract infections – antibiotic prescribing
13
1.3 Overview
1.3.1 Prescribing of antibiotics for self-limiting respiratory tract
infections in adults and children in ... setting that constituted 77.8% of the weight of
NICE clinical guideline 69 – respiratory tract infections – antibiotic prescribing
17
this guideline because acute rhinosinusitis is the terminology...
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Báo cáo Y học: Probing intermolecular protein–protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET) potx
Ngày tải lên :
08/03/2014, 09:20
... living cells (Eur. J. Biochem. 269) 5077
Probing intermolecular protein–protein interactions in the
calcium-sensing receptor homodimer using bioluminescence
resonance energy transfer (BRET)
Anders ... agonist-induced
alterations in BRET signal intensities reflecting 7TM dimer
rearrangement as a result of the activating twist in the ATDs
of the CaR homodimer. Further investigations into the
signal ... AT
1a
Rand
AT1aD359-GFP
2
displayed similar binding characteristics
in a [I
125
]angiotensin II whole cell binding assay (data not
shown). These observations are in excellent agreement with
the findings of another group...
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Báo cáo khoa học: Supramolecular calsequestrin complex Protein–protein interactions in chronic low-frequency stimulated muscle, postnatal development and ageing pot
Ngày tải lên :
08/03/2014, 10:20
... overlay
method in determining protein linkage. Its greatest advant-
age is the direct visualization of protein–protein interactions
under controlled conditions. In contrast, other established
protein biochemical ... reduction in
calsequestrin binding to these sarcoplasmic reticulum ele-
ments. The calsequestrin-binding protein junctin was not
affected by the muscle transformation process. The increase
in calsequestrin ... protein–protein interactions.
Slow CSQ might be involved in a more indirect type of
physiological coupling process in transformed fibers, while
fast CSQ appears to be a directly interacting endogenous
regulator...
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Reproductive Tract Infections: An Introductory Overview pot
Ngày tải lên :
14/03/2014, 12:20
... and uncomfortable
urination
Cervical infection
Urethral infection
Often no symptoms
Bartholin’s abscess
Cervical infection
Urethral infection
Frequent/ painful urination
Bartholinitis
Majority are ... of infection.
The diagram
1
below illustrates the reproductive tract of women. Infections in the area of the vulva,
vagina, or cervix are referred to as lower reproductive tract infections. Infections ... vaginal secretions
Amsel diagnostic criteria for bacterial vaginosis
Prevention
Treatment
Sites of Reproductive
Tract Infections
Reproductive Tract Infections in Women
Lower Reproductive Tract Infections
Ovary
Uterus
Fallopian...
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Báo cáo khoa học: Nature, nurture and neurology: gene–environment interactions in neurodegenerative disease docx
Ngày tải lên :
16/03/2014, 19:20
... expansions, encoding
polyglutamine tracts in different proteins, suggesting
that these diseases may involve overlapping molecular
mechanisms of pathogenesis involving toxic gain-
of-function of ... progress has been made
in identifying genetic factors contributing to PD in
recent years [135]. Low concordance for clinical disease
in monozygotic twins indicates environmental in uen-
ces on PD ... (2002) Increased
huntingtin protein length reduces the number of
polyglutamine-induced gene expression changes in
mouse models of Huntington’s disease. Hum Mol Genet
11, 1939–1951.
72 Cha JH, Kosinski...
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Báo cáo khoa học: Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations pot
Ngày tải lên :
16/03/2014, 22:20
... alternating ATAT tracts [6,7],
resulting in a preference for binding to the DNA
in the order AATT > TAAT ¼ TTAA ¼ ATAT >
TATA [8].
For AATT tracts, binding of the drug can be divi-
ded in two ... it is interesting that the guanine amino
group may be in uenced by this contact. We com-
pared the interaction energies in both a planar and a
nonplanar guanine G9 amino group. The HF interac-
tion ... with the minor groove binding drug netrop-
sin. Biochemistry 36, 4792–4799.
13 Patel DJ (1982) Antibiotic–DNA interactions – inter-
molecular nuclear Overhauser effects in the netropsin-
d(CGCGAATTCGCG)...
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Reproductive Tract Infections: An Introductory Overview pptx
Ngày tải lên :
22/03/2014, 12:20
... Infections
Reproductive Tract Infections in Women
Lower Reproductive Tract Infections
Ovary
Uterus
Fallopian Tube
Cervix
Vagina
Vulva
Upper Reproductive Tract
Infections
Lower Reproductive Tract
Infection
s
Reproductive ... and uncomfortable
urination
Cervical infection
Urethral infection
Often no symptoms
Bartholin’s abscess
Cervical infection
Urethral infection
Frequent/ painful urination
Bartholinitis
Majority are ... Transmitted Infections and HIV/AIDS
Reproductive Tract Infections and Family Planning
Human Papilloma Virus and Cervical Cancer
Adolescents and Reproductive Tract Infections
Reproductive Tract Infections,...
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Báo cáo khoa học: Protein interactions in the sumoylation cascade – lessons from X-ray structures pdf
Ngày tải lên :
30/03/2014, 04:20
... reaction.
Abbreviations
APPBP1, APP binding protein 1; CtBP, C-terminus binding protein; CTD, C-terminal domain; E1, activating enzyme; E2, conjugating enzyme;
E3, ligase; HECT, homologous to E6AP C-terminus; IR, internal ... in
Nedd8, and Arg72 in ubiquitin (highlighted in yellow
in Fig. 2C). Matching E1 residues are Thr149 in
uba2, Arg190 in uba3 and Gln608 in uba1 (high-
lighted in purple in Fig. 3E). Interestingly, ... motif (SIM) and a C-terminal domain (CTD) [39]. (B) Pc2
contains an uncharacterized E3 domain, a ubc9 binding domain and
a Pro-Ile-Asp-Leu-Ser motif involved in substrate binding [53].
(C) RanBP2,...
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