functional and molecular aspects of glucocorticoids in the endocrine pancreas and glucose homeos

Báo cáo y học: "Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications" pps

Ngày tải lên : 10/08/2014, 21:23

... tyrosine kinase, and results in the phosphorylation of these proteins [38] These actions affect the activation of further downstream PI3K/protein kinase B (Akt) and mitogenactivated protein kinase ... [69-82] The compounds currently in development are heterocyclic compounds containing components that structurally mimic the purine ring of adenosine and become inserted into the ATP-binding site of ... effects of ATO and MEK inhibition, as well as ATO and FLT3 inhibition, on FLT3-ITD cells [101] The combination of ATO and AG1296, an FLT3 inhibitor, profoundly inhibited the growth and induced...

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Báo cáo y học: "Molecular evolution of neuropeptides in the genus Drosophila'''' potx

Ngày tải lên : 14/08/2014, 20:22

... profiling of the ring gland The ring gland contained the adipokinetic hormone (AKH; pQLTFSPDWa), the AKH processing intermediate pQLTFSPDWGK, myosuppressin (MS), corazonin, corazonin3-11, the ... that store and release peptide hormones are the ring gland, and the thoracic and abdominal perisympathetic organs The epitracheal cells (Inka cells) are endocrine glands along the trachea These tissues ... peptide profiling of the ring gland of different Drosophila species Direct peptide profiling of the ring gland of different Drosophila species (ai-di) Mass range 900-1,600 Da The protonated mass of...

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Essays on economic aspects of abortion in the united states

Ngày tải lên : 01/10/2015, 16:59

... place in the past decades Knowledge of these aspects will help in interpreting and put into context the results of the analysis of subsequent chapters The next section describes the purpose of the ... included the dissemination of birth control information and services These state laws survived virtually unaltered until the 1960s, and before then only the District of Columbia in 1901 and Alabama in ... groups of women? These issues can be examined in the framework of economic analysis of fertility The decision of terminating a pregnancy depends on the net benefit from another child and abortion...

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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf

Ngày tải lên : 18/02/2014, 18:20

... et al Chemokines in the joints of patients CXC chemokines C and CX3C chemokines Interleukin-8 ⁄ CXCL8 (a ligand of CXCR1 and CXCR2) was the first chemokine identified to be involved in leukocyte ... cytokines, including IL-1b, TNF-a and IFN-c (B) Chemokines expressed in the joint recruit leukocytes into the joints In addition to functioning in cell trafficking, several chemokines have other biological ... subclasses include the CC chemokines (where the cysteines are neighboring) and the CXC chemokines (where the cysteines are separated by one amino acid) The CXC chemokines mainly act on neutrophils and...

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Báo cáo khoa học: Structural and functional roles for b-strand 7 in the a-crystallin domain of p26, a polydisperse small heat shock protein from Artemia franciscana pdf

Ngày tải lên : 07/03/2014, 12:20

... domain The interface between monomers of a dimer involves interaction between strands b2 and b6 of neighboring monomers The p26 modiﬁcations examined in this study are not located in either of these ... contact of b-strand 10 from the C-terminal extensions of monomers A and D with b-strands and in the a-crystallin domain of monomers C and B, respectively (Fig 8) A more prominent dimer–dimer interface ... with molecular modeling of protein structure, indicate that b-strand of the a-crystallin domain is an integral component of the p26 dimer–dimer interface in polydisperse sHSPs p26 chaperoning...

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Báo cáo khóa học: Protein assembly of photosystem II and accumulation of subcomplexes in the absence of low molecular mass subunits PsbL and PsbJ pdf

Ngày tải lên : 30/03/2014, 13:20

... and PsbJ is critical in providing proper docking sites, either directly or indirectly, by modifying the conformation of PSII on the lumenal side, making efﬁcient binding of PsbQ and PsbP of the ... accumulating all three proteins of the OEC and traces of the D2 and CP43 core proteins as well (Fig 1B) The presence of minor amounts of D2 in both DpsbE and DpsbF supports the suggestion that the ... always hold true In rapidly expanding young leaves in particular, some of the PSII core proteins and all of the OEC proteins can accumulate in thylakoids in the absence of any assembly of PSII, as...

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molecular and cellular biology of neuroprotection in the cns - christian alzheimer

Ngày tải lên : 08/04/2014, 12:51

... develops and tests new hypotheses using animal models of acute and chronic brain injury Although many of the new findings hold promise for therapeutic interventions, their translation into clinically ... processes that determine the fate of CNS neurons in the face of acute or chronic insults The book is written mostly from the viewpoint of the basic scientist who works at the cellular and molecular level, ... morphological and biochemical features of either apoptosis or necrosis depending on the severity of the insult, with more fulminant insults causing rapid energy failure because of lack of ionic homeostasis...

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Báo cáo khoa học: " Science review: Mechanisms of impaired adrenal function in sepsis and molecular actions of glucocorticoids" pdf

Ngày tải lên : 12/08/2014, 20:20

... artery, the renal artery and the aorta form rich plexuses in the cortex and supply the gland The plexuses are continuous with the sinuses of the medulla, which drain into the central vein of the ... medulla The right adrenal vein drains into the inferior vena cava and the left into the renal vein Hence, the rich blood supply required by the organ and the limited venous drainage (a single vein) ... maintain normal rates of secretion for more than a few minutes in the absence of continuing biosynthesis Thus, the rate of secretion is directly proportional to the rate of biosynthesis In other...

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Báo cáo y học: "Survivors of war in the Northern Kosovo (II): baseline clinical and functional assessment and lasting effects on the health of a vulnerable population" ppsx

Ngày tải lên : 13/08/2014, 14:20

... other mental disorders All the team members attended a training workshop, where the principles of the study instruments and procedures were explained They took the parts of the interviewer and ... which indicated that the difference in the strength of dominant and nondominant hands was less in victims Five victims had no strength in either hand; two had no strength in the right hand, and ... families were given vouchers that outlined the objectives and the procedure of the study, including the offer of a free medical examination and treatment in the municipal family health centre If...

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An investigation into linguistic features of participants in the processes in english and vietnamese from the functional grammar aspect

Ngày tải lên : 14/05/2016, 18:39

... system of a language construes experience into the small set of domains of meaning, which differ according to the process itself and the nature of participants involved in it In English, there ... with the verbs of sensing, First of all, when describing the features of participants in the feeling, thinking such as love, like, think, remember… Behavier processes, we find out the distinctions ... learners of English in their learning nominal groups or by finite and non finite clauses in English In Vietnamese, there is no concept of finite or non- finite clauses The Attribute, Identifier often...

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Cambridge.University.Press.The.Crisis.of.Literature.in.the.1790s.Print.Culture.and.the.Public.Sphere.Nov.1999.pdf

Ngày tải lên : 21/09/2012, 11:00

... Echoes of their mix of promise and threat, anticipation and dread, resound in the writings of the eighteenth and early nineteenth centuries in Britain – a time and a place when the newly disturbing ... these values, could be contained The emotional intensity of the backlash against the intrusions of these subaltern groups suggests the importance of reading these developments in ways which interfuse ... every rank, of every age, and of both sexes They are intimately acquainted with every language, the dead as well as the living To the cultivation of letters they join that of the arts; and the mechanics...

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Báo cáo y học: "An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report"

Ngày tải lên : 25/10/2012, 10:06

... at the carpal-metacarpal joint at the base of the thumb The report stated that the radiographs were otherwise normal The patient's symptoms worsened with increased pain and swelling over the ... deposits in the wrist due to gout [6,8,9] The prevalence of gout in the USA ranges between 0.5–2.8% in men and 0.1–0.6% in women [2] The prevalence rises to 4.4% of men and 1.8% of women over the ... any joint including the ankle, knee, hand, wrist, elbow, sacroiliac joint and other joints of the spine, however most commonly occurs in the lower extremity In this case, although the patient had...

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Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"

Ngày tải lên : 31/10/2012, 17:11

... Treatment against Cirrhosis), is a multicenter study of the potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease [8] In this study, 391 of the 1045 ... rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely used in patients receiving interferon therapy Treatment of advanced ... transplant outcome, and the difficulties in treatment of the infection following LT [12], it is reasonable to emphasize the importance of pretransplant treatment of HCV The International Liver...

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Seawater Purification Experiment and Consideration about Photoreactivation of Coliforms in the Inside of Seawater

Ngày tải lên : 05/09/2013, 09:08

... to the profile of fecal coliforms, the number of fecal coliforms clearly increased after the rain due to the influence of CSO The influence of CSO occurred predominantly after the rain rather ... (44% of total days) outside against the 67days (64% of the total days) inside the purification zone The ranked days were 20 point higher inside rather than outside On the other hand, the number of ... to the inflow of sea water to the purification zone caused by the tides and also due to the inflow during the high tide at the end of silt fences located at the water’s edges Concerning to the...

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A study of words in the language of sports in english and vietnamese

Ngày tải lên : 26/11/2013, 13:19

... occurring in the students' tests *try blocked, *fail completing, *require to improve, *gain the right serving, * win a point continuing, *use the bounce passing, *prevent the ball touching 23 ... line instead of goal line, * two in zero instead of two the second verb into the V-ing or V-ed form They were found that to nil students chose *try blocking instead of try to block, *deemed having ... Regarding Their Attitudes in Sports twenty-two at the time of surveying Most of them are male (82%) The findings in table 4.2 show that the majority of the subjects and nearly 20% female However,...

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Tài liệu Identifying and Analyzing Knowledge Management Aspects of Practices in Open Source Software Development pdf

Ngày tải lên : 24/01/2014, 00:20

... software engineering 4.1 Needs in software engineering The ﬁeld of software engineering have some interesting knowledge related characteristics; software development is knowledge-intensive (Lindvall ... computing The ease of access to almost any kind of information at any time in any place increases the value of cognitive skills of individuals Choosing the right information to process i.e understand, ... Jonson School of Engineering Blekinge Institute of Technology Box 520 SE - 372 25 Ronneby Sweden This thesis is submitted to the School of Engineering at Blekinge Institute of Technology in partial...

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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx

Ngày tải lên : 15/02/2014, 13:20

... useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered Vol 45 / No RR-4 MMWR and the vaccinee’s age at the time of vaccination ... resurgence in the incidence of TB occurred in the United States and included increases in the number of TB cases among adults and children and outbreaks of multidrug-resistant TB (MDR-TB) involving ... Control and Prevention The role of BCG vaccine in the prevention and control of tuberculosis in the United States: a joint statement by the Advisory Council for the Elimination of Tuberculosis and the...

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Tài liệu Gulf War and Health: Volume 4. Health Effects of Serving in the Gulf War docx

Ngày tải lên : 16/02/2014, 01:20

... agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities The Council ... achievements of engineers Dr Wm A Wulf is president of the National Academy of Engineering The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of ... services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the National...

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Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-afﬁnity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

Ngày tải lên : 19/02/2014, 12:20

... conformation of the PDZ binding domain of ephrinB2(301–333) is essentially independent of tyrosine phosphorylation within the SH2-binding element of ephrinB2(301–333) On the other hand, tyrosine phosphorylation ... of the GST-PDZ protein Therefore, the GST-PDZ fusion protein was used for all other binding experiments including the GST pull-down experiments (see below) On the other hand, the SH2 domain of ... whether the binding of the PDZ domain of PDZRGS3 affects binding of the Grb4 SH2 domain to phosphorylated peptides, through studies of ternary interactions among the PDZ domain, the phosphotyrosine...

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Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx

Ngày tải lên : 20/02/2014, 03:20

... in the process of DNA laddering (as is the case with EndoG) rather than in the production of large-sized DNA fragments, considering the timing of uptake of the mitochondria in the autophagosome, ... becomes acidic in the ﬁnal step of PND [22,23] DePsipher staining of the macronucleus appeared initially during the stage of autophagosome formation, and persisted until resorption of the parental ... which appear to be involved in the ﬁnal resorption of the parental macronucleus during PND in T thermophila, and suggested the involvement of mitochondria in this process [19] In mammalian apoptosis,...

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