expert group to review the rates of agency charges payable to department of posts for operation of small savings instruments

Tài liệu High-level Expert Group on reforming the structure of the EU banking sector docx

Tài liệu High-level Expert Group on reforming the structure of the EU banking sector docx

Ngày tải lên : 16/02/2014, 10:20
... amendments to the use of bail-in instruments as a resolution tool In addition to the use of RRPs, the Group also strongly supports the use of designated bail-in instruments within the scope of the BRR, ... grateful for their contribution Erkki Liikanen The Chairman of the High-level Expert Group HLEG ii SUMMARY OF THE PROPOSAL The High-level Expert Group was requested to consider whether there is ... and the exante creditor hierarchy is to be respected However, the Group has come to the conclusion that there is a need to further develop the framework, so as to improve the predictability of the...
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Báo cáo y học: " Bench-to-bedside review: The role of the alveolar epithelium in the resolution of pulmonary edema in acute lung injury" pps

Báo cáo y học: " Bench-to-bedside review: The role of the alveolar epithelium in the resolution of pulmonary edema in acute lung injury" pps

Ngày tải lên : 12/08/2014, 20:20
... edema [59] The loss of epithelial tight junctions might lead to decreased AFC due to the loss of polarity of epithelial cells In addition, the loss of epithelial tight junctions may lead to increased ... and the route of delivery of treatment In addition, most of the research discussed here has been done by administering the modulator of AFC before the lung injury, raising the question of whether ... possible therapeutic approach to ALI The use of growth factors in the treatment of ALI may be critical, because no amount of stimulation of the transport Finally, although little research into the...
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Báo cáo khoa học: "Bench-to-bedside review: The role of glycosaminoglycans in respiratory disease" potx

Báo cáo khoa học: "Bench-to-bedside review: The role of glycosaminoglycans in respiratory disease" potx

Ngày tải lên : 13/08/2014, 03:20
... receptor for group A streptococci (GAS) colonization of the pharynx in vivo The recognition of CD44 as a receptor for a major microbial pathogen adds a new dimension to the multifaceted role of ... growth factor; TGF, transforming growth factor; VEGF, vascular endothelial growth factor may also serve as storage forms for rapid mobilization of chemokines without the need for protein synthesis ... overhydration of the interstitium, contributing to the inflammatory mechanism [11] That the overall synthesis of hyaluronic acid in the organism is considerable and that the hyaluronic acid pool of the...
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Báo cáo khoa học: "Bench-to-bedside review: The role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury" pot

Báo cáo khoa học: "Bench-to-bedside review: The role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury" pot

Ngày tải lên : 13/08/2014, 03:20
... the potential direct effects of APC on the endothelium Direct effects of APC on the vascular endothelium are biologically plausible because this is the site of protein C activation, the endothelium ... modulation of endothelium by activated protein C Although sepsis often causes clinically apparent injury to multiple organs, the major common denominator of injury is the vascular endothelium In the ... (inhibitor of apoptosis protein) and BCL-2, were upregulated by APC, whereas there was suppression of the apoptotic Page of (page number not for citation purposes) genes calreticulin and TRMP-2 Furthermore,...
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Báo cáo y học: "Bench-to-bedside review: The evaluation of complex interventions in critical care" ppsx

Báo cáo y học: "Bench-to-bedside review: The evaluation of complex interventions in critical care" ppsx

Ngày tải lên : 13/08/2014, 08:21
... perceive their practice to be considerably different to that delivered in the ‘usual care’ arm of the trial and, therefore, question the applicability of the findings to their patients The outcome ... resuscitation protocol for patients with severe sepsis, the review must examine the supportive evidence for each of the component parts There must be a rationale for combining the components and for the choice ... ways to ensure compliance with a protocol, refined protocols with more of one component and less of others, extending the scope of the new process to other populations or moving the process into...
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Báo cáo y học: "Bench-to-bedside review: The value of cardiac biomarkers in the intensive care patient" pdf

Báo cáo y học: "Bench-to-bedside review: The value of cardiac biomarkers in the intensive care patient" pdf

Ngày tải lên : 13/08/2014, 10:20
... and the biomarkers, the rapid appearance of the biomarkers, the correlation between the biomarkers and the severity of the disease, the provision of prognosis, and the ease of performing the ... infrequent There are a number of reasons for this, including the high sensitivities of the new-generation assays, the use of low cutoff points and the imprecision of the assays In view of this uncertainty, ... adds value to the diagnostic process The helpfulness of the biomarker information will depend on the way in which it is used (for example, sampling time, the cutoff points chosen), the clinician’s...
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Báo cáo y học: "Bench-to-bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the measurement of cardiac output" ppsx

Báo cáo y học: "Bench-to-bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the measurement of cardiac output" ppsx

Ngày tải lên : 13/08/2014, 11:23
... order for the study to confirm the efficacy of the new tool To allow a conclusion to be drawn from the data, the authors should have made an a priori description of what they perceived to be ... if the reference technique uses an average of four curves (CE of 4%), then for the same technique as before (error of 15%) the PE for the Bland-Altman plot is ± 30%, Page of (page number not for ... can range from 5% to 15% depending on the technique used The main limitation of this ± 30% cutoff, therefore, is that it relies on the fact that the precision of ITD is always the same and is usually...
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Báo cáo y học: "Bench-to-bedside review: The promise of rapid infection diagnosis during sepsis using polymerase chain reaction-based pathogen detection" pptx

Báo cáo y học: "Bench-to-bedside review: The promise of rapid infection diagnosis during sepsis using polymerase chain reaction-based pathogen detection" pptx

Ngày tải lên : 13/08/2014, 16:20
... to be the result of the organism’s not being included in the particular PCR panel [41] Similar considerations apply to the application of PCR to other clinical samples such as sputum for the diagnosis ... oligonucleotide primers, short pieces of synthesised DNA that bind to either end of the sequence and form the starting point for DNA replication by DNA polymerase For bacterial pathogens, two basic ... evaluating the use of SepsiTest™ in a clinical setting Key issues in the application of polymerase chain reaction to the diagnosis and management of sepsis The application of PCR techniques to detect...
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Báo cáo y học: "Bench-to-bedside review: The role of β-lactamases in antibiotic-resistant Gram-negative infections" potx

Báo cáo y học: "Bench-to-bedside review: The role of β-lactamases in antibiotic-resistant Gram-negative infections" potx

Ngày tải lên : 13/08/2014, 20:21
... Descriptions of β-lactamase groups Cephalosporinases Group 1/Class C cephalosporinases are among the most abundant β-lactamases on the basis of the number of organisms that produce these enzymes These ... according to the amino acid sequences of the enzymes or according to their inactivating properties for different classes of β-lactams The molecular classification scheme divides β-lactamases into four ... on the amino acid sequences of the proteins [8-10], whereas numerically more functional groups have been assigned based on the hydrolysis and inhibition profiles of the enzymes [7,10,11] The...
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Tài liệu Guide to Using International Standards on Auditing in the Audits of Small- and Medium- sized Entities pptx

Tài liệu Guide to Using International Standards on Auditing in the Audits of Small- and Medium- sized Entities pptx

Ngày tải lên : 18/02/2014, 05:20
... performed • The need to perform further audit procedures to address the potential for management override of controls or other fraud scenarios • The need to perform specific procedures to address ... cross-referencing to the ISAs sufficient for you to easily refer to the ISAs while reading the Guide? Do you believe that the Guide has appropriately integrated all of the relevant ISAs into the audit ... exclusively on the ISAs that apply to audits of historical financial information 10 HOW TO USE THE GUIDE Cross-references The following table cross-references the ISAs (relevant to SME auditing) to the...
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Báo cáo khoa học: Gene expression silencing with ‘specific’ small interfering RNA goes beyond specificity – a study of key parameters to take into account in the onset of small interfering RNA off-target effects potx

Báo cáo khoa học: Gene expression silencing with ‘specific’ small interfering RNA goes beyond specificity – a study of key parameters to take into account in the onset of small interfering RNA off-target effects potx

Ngày tải lên : 07/03/2014, 05:20
... normalization Furthermore, in order to consider the purity and quality of the mRNA, a second normalization step was performed on the basis of the average of fluorescence intensities measured for a set of housekeeping ... decreased thereafter Thus, according to our data, the undesired effects of siRNA seem to appear in a transient way Another key parameter to take into account could be the length of the transfection ... particular targets were chosen on the basis of their interest for other research programmes in our laboratory The efficiency of these siRNAs at concentrations ranging from nm to 100 nm was first demonstrated...
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STERN REVIEW: The Economics of Climate Change potx

STERN REVIEW: The Economics of Climate Change potx

Ngày tải lên : 08/03/2014, 06:20
... STERN REVIEW: The Economics of Climate Change The first half of the Review considers how the evidence on the economic impacts of climate change, and on the costs and benefits of action to reduce ... used in the Review all point to the desirability of strong action, given estimates of the costs of action on mitigation But how much action? The Review goes on to examine the economics of this ... because of the size of the adverse climate-change impacts in the worst-case scenarios The ultimate concentration of greenhouse gases determines the trajectory for estimates of the social cost of carbon;...
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Guide to Using International Standards on Auditing in the Audits of Small- and Medium-Sized Entities doc

Guide to Using International Standards on Auditing in the Audits of Small- and Medium-Sized Entities doc

Ngày tải lên : 29/03/2014, 22:20
... relevant to the group audit, − The component auditor's professional competence, − Whether the group engagement team will be able to be involved in the work of the component auditor to the extent ... require the terms of the audit engagement to be revised and whether there is a need to remind the entity of the existing terms of the audit engagement (Ref: Para A28) 210.14 The auditor shall ... Statements The Responsibilities of the Auditor Description • The accounting framework to be used • Objective of the audit of financial statements and the anticipated form of auditor’s report or other...
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Báo cáo y học: " Pragmatic randomised controlled trial of group psychoeducation versus group support in the maintenance of bipolar disorder" pps

Báo cáo y học: " Pragmatic randomised controlled trial of group psychoeducation versus group support in the maintenance of bipolar disorder" pps

Ngày tải lên : 11/08/2014, 15:22
... conduct of the study in the North West area of England SJ is the Chief Investigator for the PARADES Programme of Research and responsible for the measurement of processes in the study LR is the study ... given for each session covering the content of that session The groups are run in a collaborative workshop with a brief didactic introduction of the topic for the session and the rest of the work ... which reflects the practice of expert patient and some types of support groups for bipolar disorder in England The support groups aim to enable the group participants to devise ways of remaining...
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Báo cáo y học: "Clinical review: The management of hypertensive crises" ppsx

Báo cáo y học: "Clinical review: The management of hypertensive crises" ppsx

Ngày tải lên : 12/08/2014, 19:22
... triggering factor superimposed on pre-existing hypertension The risks for developing malignant hypertension are related to the severity of the underlying hypertension, and therefore the role of mechanical ... natriuresis further simulates the release of vasoconstrictor substances from the kidney The release of vasoconstrictor substances from the kidney has long been postulated to play a central role in the pathophysiology ... age Coarctation of the aorta The factors that lead to the severe and rapid elevation of blood pressure in patients with malignant hypertension are poorly understood The rapidity of onset suggests...
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Báo cáo khoa học: "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury" pptx

Báo cáo khoa học: "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury" pptx

Ngày tải lên : 12/08/2014, 19:22
... transmembrane adhesion receptors such as integrins These receptors transmit forces from the surrounding matrix to the cytoskeleton via the focal adhesion complex [11] When the basement membrane is ... RM Furthermore, those investigators showed that a single sustained inflation to 30 cmH2O boosted the ventilatory cycle onto the deflation limb of the pressure–volume curve (Fig 1) In other words, ... does not lead to release of significant amounts of inflammatory cytokines by the lung in the absence of lipopolysaccharide challenge Likewise, in experimental studies other investigators have shown...
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Báo cáo y học: "Clinical review: The meaning of acid–base abnormalities in the intensive care unit – effects of fluid administration" potx

Báo cáo y học: "Clinical review: The meaning of acid–base abnormalities in the intensive care unit – effects of fluid administration" potx

Ngày tải lên : 12/08/2014, 20:20
... They are applications of the Law of Mass Action to the dissociation of water, H2CO3, HCO3–, and nonvolatile weak acids, coupled with the expression for ATOT and a statement of electrical neutrality ... changing ATOT If the SBE is below –3.0 mEq/l then there is metabolic acidosis, either primary or compensatory The deviation below zero is the increase in extracellular SID needed to correct the acidosis ... administered into the physiological milieu Their in vivo properties can therefore be described using Stewart’s physical chemical language, in other words in terms of their SID, ATOT and CO2TOT [13]...
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Báo cáo khoa học: "Equipment review: The success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation" potx

Báo cáo khoa học: "Equipment review: The success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation" potx

Ngày tải lên : 12/08/2014, 22:22
... at the tip of a transesophageal probe In order to maximize the accuracy of the device, the probe position must be adjusted to obtain the peak velocity in the aorta To transform blood flow in the ... pH to assess the adequacy of perfusion is an extremely attractive concept As a consequence of the stoichiometry of the reactions responsible for the substrate level phosphorylation of ADP to form ... designed to compare resuscitation strategies To overcome the potential for bias introduced by the absence of blinding, investigators have stressed the importance of using protocolized care for both the...
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