epidemiology of liver disease in human immunodeficiency virus infected persons

Báo cáo y học: "Formulation preference, tolerability and quality of life assessment following a switch from lopinavir/ritonavir soft gel capsule to tablet in human immunodeficiency virus-infected patients" pot

Ngày tải lên : 10/08/2014, 05:21

... Management of Protease InhibitorAssociated Diarrhea Clin Infect Dis 2000, 30:908-914 Bongiovanni M, Bini T, Chiesa E, et al.: Lopinavir/ritonavir vs indinavir/ritonavir in antiretroviral naive HIV -infected ... observed lipid lowering effect is unclear and deserves further evaluation in larger cohorts Finally, the findings of this study should be interpreted in the context of a pilot, single arm study with ... and in HDL of 4.50 mg/dL (p = 0.01) unrelated to lipid-lowering therapy, were observed at week 12 The rea- Intervention At baseline, demographic and clinical laboratory data including fasting...

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báo cáo hóa học:" Cytokine Profiles in Human Immunodeficiency Virus-Infected Children Treated With Highly Active " pdf

Ngày tải lên : 20/06/2014, 08:20

... the Institutional Review Board of Hong Kong West Hospital Cluster and The University of Hong Kong, and informed consent was obtained from the parents of all subjects Clinical findings in of the ... of HIV-1 infection and were treated with nucleoside reverse transcriptase inhibitors (zidovudine, lamivudine, didanosine, stavudine, and/or abacavir) plus protease inhibitor (indinavir, nelfinavir, ... cytokine evaluation was performed within month of starting HAART in patients, within 24 months in patients, and after 16 and 19 months in patients ELISPOT Assay Numbers of cytokine-secreting cells...

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Báo cáo y học: "Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells" docx

Ngày tải lên : 13/08/2014, 01:21

... Syndrome protein) [33], and the Ezrin Radixin Moesin (ERM) proteins Merlin [34] and cofilin [35,36] Nef associates with an activated form of PAK2 [37-39], a serine/threonine kinase important in T cell ... MAGI R5+ cells were incubated for h with 5,000 3H cpm of RT activity of VSV-G pseudotyped virus Infections and staining were performed as in Figure 1B Average percent of infected (b-galactosidase+) ... cells and reducing the percentage of resting cells Thus, stimulation in the presence of FBS may result in stronger cell stimulation than delivering the same stimulus in the presence of human A/B serum...

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Báo cáo y học: "Recent key advances in human immunodeficiency virus medicine and implications for Chin" potx

Ngày tải lên : 10/08/2014, 05:21

... starting at 14 instead of 28 weeks and continuing through breastfeeding was added as an option Although ART can be delivered safely without routine monitoring of hematology and biochemistry in ... prevention of HIV-1: evolution of a global pandemic J Clin Invest 2008, 118:1244-1254 49 McIntyre J: Use of antiretrovirals during pregnancy and breastfeeding in low-income and middle-income countries ... US National Institutes of Page of Health (NIH) earlier in 2009 was more promising, showing a 30% reduction in HIV infections [38] This result, however, was just short of the pre-defined criterion...

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Báo cáo y học: "Selective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation of HIV proteas" doc

Ngày tải lên : 13/08/2014, 01:20

... cleavage of a number of host cell proteins including actin [21], vimentin [22], Bcl-2 [13], Page of 14 poly A binding protein [23], eIF4G [24] and procaspase [25] Proteolysis of host cell factors offers ... generated by inserting the coding sequence for amino acids 1-51 of b-Gal (defined as the minimal complementary peptide in [40]) at the 3’ Page of 14 end of the MA coding region of proviral plasmid ... at a density of 1.5 × 105 cells/ml and infected with HIV-1IIIB at a multiplicity of infection of 0.01 in the presence of different NNRTI concentrations After days of incubation, infected cells...

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Báo cáo y học: "A Functional Role for ADAM10 in Human Immunodeficiency Virus Type-1 Replication" pptx

Ngày tải lên : 13/08/2014, 01:20

... cellular proteins via proteolytic cleavage In addition to its metalloprotease domain, it also contains a disintegrin domain, an EGFlike domain, a cysteine-rich domain, a transmembrane domain, and a ... metalloprotease domain potentially responsible for this increase was further investigated ADAM10 E384A plasmid contains a single inactivating point mutation in the metalloprotease domain rendering the metalloprotease ... integration of retrovirus-like DNA by human immunodeficiency virus type integrase J Virol 1995, 69:6090-6097 10 Greene WC: The molecular biology of human immunodeficiency virus type infection N...

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Báo cáo y học: " MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals" pot

Ngày tải lên : 13/08/2014, 05:21

... diagram of the overlap of miRNA profiles in patients, in stimulated PBMCs, and in virus infected PBMCs The miRNAs differentially expressed in patients, in anti-CD3 treated PBMCs, and in HIV-1 infected ... frequently changed in "Patients" (Figure 4) Interestingly, all of the down regulated miR- Figure Venn diagram of the overlap of miRNA profiles in patients, in stimulated PBMCs, and in virus infected PBMCs ... alterations with the in vivo course of HIV-1 infection miRNA profiles are changed in PBMCs treated ex vivo with T-cell activating or inactivating stimuli In seropositive individuals, HIV-1 infects only...

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Báo cáo y học: " Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys" ppt

Ngày tải lên : 13/08/2014, 01:21

... with high viral load were often below the levels of uninfected controls These findings may explain the decreased A3G levels in PBMC of infected compared with uninfected individuals reported by ... 0 uninfected asymp AIDS uninfected asymp AIDS Figure APOBEC3 mRNA levels in uninfected and SIV -infected macaques A3G (left panels) and A3F (right panels) mRNA levels were determined in uninfected ... levels of interferon-stimulated genes (ISGs) in uninfected and SIV -infected macaques Upper panels show relative MxA (A) and IP-10 (B) mRNA levels in PBMC of uninfected (triangles) and SIV-infected...

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Tài liệu THE BACTERIOLOGY OF PULMONARY TUBERCULOSIS IN A POPULATION WITH HIGH HUMAN IMMUNODEFICIENCY VIRUS SEROPREVALENCE ppt

Ngày tải lên : 15/02/2014, 13:20

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PULMONARY TUBERCULOSIS AMONG HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTED PATIENTS IN THE ERA OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) IN DAR ES SALAAM MUNICIPAL, TANZANIA pdf

Ngày tải lên : 22/03/2014, 18:20

... resources, fishing and large and small scale industries The main business activities include insurance, travel, clearing and forwarding agencies, hoteliers, printing press to distributors of industrial ... the incidence of TB in HIV -infected patients by 80% or more (Badri et al, 2002; Girardi et al, 2000) The reduction in the prevalence of TB in HIV infected patients after the introduction of HAART ... Problem statement The prevalence of TB is increasing in many countries and is the leading infectious cause of death worldwide Infection with HIV, likewise increasing in prevalence, has emerged as...

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Variation of Chest Radiographic Patterns in Pulmonary Tuberculosis by Degree of Human Immunodeficiency Virus–Related Immunosuppression pot

Ngày tải lên : 29/03/2014, 03:20

... HIV -infected patients with pulmonary TB has important clinical implications because of the increased susceptibility of HIV -infected patients to a variety of other respiratory pathogens Much of ... examine the independent relationship of CD4/ cell counts and other variables to the presence of specific chest radiograph findings An analysis pooling the findings of other reports with those of ... performed combining interstitial disease with in ltrates, there remained no significant relationship between CD4/ cell count and any in ltrates evident radiographically (with CD4/ cell counts of 0/mm3,...

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Báo cáo sinh học: " The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single human T-cell" docx

Ngày tải lên : 18/06/2014, 18:20

... cells Infection of T-cells by all three viruses CEM cells were infected individually by each of the three viruses (Fig 1) To test the infectivity of HHV-6A, CEM cells were infected with the virus ... infected cells and finally the HCV infected ones died At this point these experiments were terminated Infection of single cells Since PCR analysis showed that all three viruses were present in ... affects HCVinfected patients while the effects of HCV on HIV -infected patients are less defined and controversial [2,3] Increased morbidity in co -infected individuals would not be surprising HAART,...

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Báo cáo hóa học: " The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single human T-cell" pptx

Ngày tải lên : 20/06/2014, 01:20

... cells Infection of T-cells by all three viruses CEM cells were infected individually by each of the three viruses (Fig 1) To test the infectivity of HHV-6A, CEM cells were infected with the virus ... infected cells and finally the HCV infected ones died At this point these experiments were terminated Infection of single cells Since PCR analysis showed that all three viruses were present in ... affects HCVinfected patients while the effects of HCV on HIV -infected patients are less defined and controversial [2,3] Increased morbidity in co -infected individuals would not be surprising HAART,...

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Báo cáo hóa học: " The inhibition of the Human Immunodeficiency Virus type 1 activity by crude and purified human pregnancy plug mucus and mucins in an inhibition assay" ppt

Ngày tải lên : 20/06/2014, 01:20

... effect of mucins or the infectivity of the virus This suggested that the mucins aggregated the virus immediately and permanently However, shorter starting times of incubation of mucins and the virus ... MUC7 mucins in the inhibition of Human Immunodeficiency Virus type in an inhibition assay Virol J 2006, 3:99 Habte HH, de Beer C, Lotz ZE, Tyler MG, Kahn D, Mall AS: Inhibition of Human Immunodeficiency ... those in saliva, still remain major routes of transmission of the virus In the case of breast milk we showed that its MUC1 component inhibited the HIV-1 from infecting CEM SS cells in an in vitro...

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báo cáo hóa học:" High Prevalence of Hepatitis B Virus Markers in Romanian Adolescents With Human Immunodeficiency Virus Infection" ppt

Ngày tải lên : 20/06/2014, 08:20

... monitor key aspects of the epidemiology of hepatitis B virus (HBV) infection in Romania Program and abstracts of the 36th Annual Meeting of the Infectious Disease Society of America; November ... Chronic active hepatitis B exacerbations in human immunodeficiency virus- infected patients following development of resistance to or withdrawal of lamivudine Clin Infect Dis 1999, 28:1032-1035 Abstract ... effectiveness of antiretroviral therapy Assessing the changing incidence and prevalence of viral hepatitis markers in a cohort of HIV -infected adolescents allows us to gauge the impact of HIV infection...

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Báo cáo khoa học: "Atypical presentation of angiosarcoma of the scalp in the setting of Human Immunodeficiency Virus (HIV)" pdf

Ngày tải lên : 09/08/2014, 04:21

... Editor -in- Chief of this journal Competing interests The author declares that they have no competing interests Authors' contributions PSG participated in the treatment of the patient, collection of ... World Journal of Surgical Oncology 2009, 7:99 The impact of HIV on the South African healthcare system has been profound The total number of persons living with HIV in South Africa increased from ... an enlarging purple bruise-like lesion that develops over several months There may be intermittent bleeding, oedema or ulceration A delay in diagnosis is common in the early stages of disease...

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Báo cáo y học: " Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo" pptx

Ngày tải lên : 10/08/2014, 05:21

... doses in vivo, may have clinical utility In addition, in combination studies using both AZT and WR1065 in human TCBs, we found that addition of WR1065 to a non-saturating dose of AZT resulted in ... activity in the presence of WR1065 Furthermore, in this study we examined the in situ effect of WR1065 in a second primate species infected with an immunodeficiency virus inducing AIDS-like symptoms, ... hemocytometer Numbers of viable (unstained) cells were expressed as a percentage of total (stained plus unstained) cells To examine apoptosis as a measure of cell viability in human TCBs infected with...

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Báo cáo y học: "Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells" pptx

Ngày tải lên : 10/08/2014, 05:21

... antibodies In the presence of cell-permeable Darunavir and Indinavir [26,27], precursor autoprocessing was inhibited in a dose-dependent manner, as indicated by the appearance of increasing amounts of ... have a defined structure by itself However, it remains to be determined whether TFR regulates protease structures in an auxiliary manner during autoprocessing in the infected cell In line with ... [24], this indicated once again that inhibition of protease activity slows down protease degradation, consistent with the detection of mature protease in the presence of inhibitors Using provirus...

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Báo cáo y học: "Near full-length genome analysis of low prevalent human immunodeficiency virus type 1 subclade F1 in São Paulo, Brazil" docx

Ngày tải lên : 12/08/2014, 04:21

... indicated an African origin of subtype F epidemic in Romania [16,19] A significantly high proportion of HIV-1 F1 strains were isolated from 11 out of 18 patients infected with non-B viruses of ... by a single or a very small group of individuals infected with genetically related viruses then spread from person to person till it took firm hold in the current epidemic Our findings in this ... is involved in intracellular trafficking of plasma membrane-associated proteins [48,49] It has been shown that duplication of the PTAPP late protein can considerably affect the Tsg101 binding...

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