energy needs assessment and requirements in humans

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)

Ngày tải lên : 18/10/2013, 00:15
... sampling until injection to GC, and from the standard solution to a test specimen) In principle, the sampling, extraction and GC analysis should be made at low temperature, in a gastight state and ... mg/mL), and kept airtightly in a refrigerator A 5-µL volume of the above solution is placed using a microsyringe in a glass vial containing mL of dimethyl sulfoxide (DMSO), capped airtightly and ... nitrite inhalant in rat and human blood: application for pharmacokinetic investigations J Chromatogr B 734:83–89 11) Kielbasa W, Fung HL (2000) Pharmacokinetics of a model organic nitrite inhalant and...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)

Ngày tải lên : 18/10/2013, 00:15
... eye mucosa and the skin results in its poisoning In the murder terrorism with VX taking place in Osaka, Japan, 1994, VX was sprayed on the back of the neck of the victim using a syringe (the exposure ... DAEMS in serum are about 50 ng/mL in the scan mode and about ng/mL in the SIM mode > Figure 2.3 shows a TIC, mass chromatograms and mass spectran for EMPA (1 µg/mL) extracted from human serum In humans, ... resulting acetonitrile layer is transferred to another test tube To the remaining aqueous phase, mL acetonitrile is again added, shaken and centrifuged The acetonitrile layers obtained are combined,...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)

Ngày tải lên : 24/10/2013, 19:15
... using benzene/n-hexane/diethylamine (25:10:1, v/v) as eluting solvent for getting each cannabinoid standard ∆9-THC, CBD and CBN are separately dissolved in ethanol to prepare 0.05–0.5 mg/mL standard ... factory worker was killed by being caught in a machine during working with it The concentrations of ∆9-THC-11-oic acid measured by GC/MS were 78 and 12 ng/mL in urine and blood, respectively; 0.7 ... ME, Sadler BM, Brine D et al (1983) Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women Clin Pharmacol Ther 34:352–363 2) Agurell S, Halldin M, Lindgren J-E et...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)

Ngày tải lên : 24/10/2013, 19:15
... Main metabolic pathways of morphine, heroin and codeine The thick and thin arrows show the main and minor metabolic pathways, respectively ⊡ Figure 3.1 196 Morphine and its analogues GC and ... morphine Trends Neurosci 23:436–442 205 206 Morphine and its analogues 8) Matsubara K, Fukushima S, Akane A et al (1992) Increased urinary morphine, codeine and tetrahydropapaveroline in Parkinsonian ... Poppy seed ingestion and opiates urinalysis: a closer look J Anal Toxicol 14:308–310 10) Hasegawa M, Maseda C, Kagawa M et al (1992) Morphine and codeine being contained in poppy seeds and poppy...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)

Ngày tải lên : 24/10/2013, 19:15
... In > Table 5.1, clinical symptoms according to the concentrations of methemoglobin are presented ⊡ Table 5.1 Clinical symptoms appearing according to methemoglobin concentrations Methemoglobin ... Cyanosis in infants caused by nitrates in well water JAMA 257:2788–2792 12) Fan AM, Steinberg VE (1996) Health implications of nitrate and nitrite in drinking water: an update on methemoglobinemia ... containing nitrate salt can be considered However, a form or a product containing nitrate ingested could not be specified in the present poisoning case Notes a) When nitrite is present in blood,...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)

Ngày tải lên : 24/10/2013, 19:15
... determination of methemoglobin in blood containing carboxyhemoglobin Forensic Sci Int 17:177–184 7) Sato K (1983) A method for determination of methemoglobin in blood containing carboxyhemoglobin ... Microdetermination of oxyhemoglobin, methemoglobin and sulfhemoglobin in a single sample of blood J Biol Chem 126:655–662 2) Leahy T, Smith R (1960) Notes on methemoglobin determination Clin Chem ... is read using cuvette A as reference, and this reading is A1 After allowing cuvette D to stand for 10 min, the absorbance at 630 nm is read using cuvette C as reference, and this reading is A3...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)

Ngày tải lên : 29/10/2013, 01:15
... suggesting a relatively short period between the times of his ingestion and death In addition, the ratios of cocaine to BE in blood and in the brain, and the brain-to-blood ratios of cocaine and ... 10.6 on average for urine sampled 0–8 h after the inhalation The ratios increased according to the increase in time interval between the inhalation and samplings [13–15] In the present case, the ... EL et al (1977) Cocaine and benzoylecgonine excretion in humans J Forensic Sci 22:697–707 15) Amber J (1985) The urinary excretion of cocaine and metabolites in humans: a kinetic analysis of published...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)

Ngày tải lên : 29/10/2013, 02:15
... two autopsy cases of pentazocine poisoning, its concentrations were 9.2 and 3.3 µg/mL in blood, 43 and 34 µg/g in the liver, and not detectable and 4.5 µg/mL in urine, respectively [12] The blood ... retention times of 3–7 and 7–8 min, respectively The amount of pentazocine and IS spiked into mL of blank whole blood or urine was equally 50 ng ⊡ Figure 5.2 222 Pentazocine Pentazocine In two autopsy ... pentazocine in blood The recovery of pentazocine using the Sep-Pak C18 cartridge was close to 100 % for both whole blood and urine [8] In this method, dextromethorphan is used as IS; the drug is being...
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Đề tài " Energy Sector Liberalisationand Privatisation in Thailand - Tự do hóa ngành năng lượng và Tư nhân ở Thái Lan "

Đề tài " Energy Sector Liberalisation and Privatisation in Thailand - Tự do hóa ngành năng lượng và Tư nhân ở Thái Lan "

Ngày tải lên : 07/11/2013, 02:15
... Maintenance Companies Bus MainTasks National Energy Policy Office Energy Industry Act • In order to introduce retail competition and create a power pool, a new energy law will be needed • Energy ... Management of the Energy Sector • Since there is no Energy Ministry in Thailand, responsibilities related to energy are scattered across Ministries • The National Energy Policy Council (NEPC) ... National Energy Policy Office Competition in Gas Supply Industry • NEPO’s plan for regulatory & industry structure of GSI – – – – – – – division of transmission and trading licensing all operators independent...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)

Ngày tải lên : 08/11/2013, 01:15
... (ed) (1992) Standard Methods of Chemical Analysis in Poisoning – With Commentary – Nanzando, Tokyo, p 43 and p 151 (in Japanese) 3) Cody JT (2000) Hallucinogens In: Bogusz MJ (ed) Handbook of Analytical ... center were 0.5–1.9 ng/mL in blood and 0.2–7.7 ng/mL in urine [4] References 1) Tu AT (1999) Principle of Toxicology – Science of Poisons – Jiho Inc., Tokyo, pp 108–109 (in Japanese) 2) The Pharmaceutical ... to contain LSD, the drug is extracted by adding % tartaric acid aqueous solution and by shaking it for This procedure is repeated six times and the tartarate extract solutions are combined After...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 25)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 25)

Ngày tải lên : 08/11/2013, 01:15
... determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine, and 3,4-methylenedioxyethylamphetamine in urine by solid-phase extraction and GC-MS: ... from the Greek and Latin origins; “en”, “gen” and “tactus” mean “within”, “produce” and “touch”, respectively Therefore, the word means “to produce a touching within” [1] b) MDA, MDMA and MDEA are ... catecholamine (including serotonin) release and blockade of reuptake resulting in cardiac and central nervous system effects [15] The effects of MDMA vary depending on its doses, frequency and duration...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 26)

Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 26)

Ngày tải lên : 08/11/2013, 01:15
... Medical 243 244 Phencyclidine Center At admission, he stared straight ahead, following commands but not responding verbally; the levels of serum creatinin kinase and aspartate aminotransferase were ... (GABA), and also a potent inhibitory neurotransmitter [2] GHB has a distinct presynaptic receptor in the brain [3], and is an agonist of GABAB receptors [4–8] GHB was first synthesized in 1960 and ... dichloromethane containing cyclized GHB is more than 100 µL in the vial, the proportion of dichloromethane gas, being contained in the headspace vapor to be injected after heating, becomes too high;...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 27) ppt

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 27) ppt

Ngày tải lên : 15/12/2013, 12:15
... Poisoning due to psychotropic agents Adverse Drug React Acute Poisoning Rev 4:83–126 3) Geraut A, Kintz P, Traqui A et al (1994) Toxicological findings in a fatality involving chlorpromazine Bull Int ... distinct peaks However, peaks of perazine, prochlorperazine, thiethylperazine and perphenazine were small and also interfered with by impurity peaks; low concentrations of these compounds in human ... following LC/MS becomes very useful LC/MS analysis [8] See [8] Reagents and their preparation i Reagents Prochlorperazine, trifluoperazine, perphenazine, fluphenazine, propericiazine and thioridazine...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 28) pptx

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 28) pptx

Ngày tải lên : 15/12/2013, 12:15
... and dyskinesia of the face, appeared Thus, diphenhydramine was injected into her intravenously; she recovered days after admission For the male baby, similar treatments, such as intravenous injection ... obtained TICs and SIM chromatograms of haloperidol, bromperidol and their reduced forms are shown in > Fig 2.2 The detection limit was about 10 pg in an injected volume for both haloperidol and ... (1995) Simultaneous determination of haloperidol and its neurotoxic metabolite in plasma and brain tissue from schizophrenic patients treated with haloperidol using HPLC and solidphase extraction...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 29) ppt

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 29) ppt

Ngày tải lên : 15/12/2013, 12:15
... antidepressants Compound amitriptyline amoxapine carbamazepine clomipramine desipramine dosulepin imipramine lofepramine maprotiline mianserin nortriptyline setiptiline trimipramine** Therapeutic level* ... HPLC-UV A: carbamazepine, B: desipramine, C: maprotiline, D: nortriptyline, E: amoxapine, F: setiptiline, G: mianserin, H: imipramine, I: amitriptyline, J: trimipramine, K: clomipramine not be separated ... 1.24 0.66 1.45 0.53 1.00 (15.195 min) (24.237 min) (14.003 min) (38.997 min) (18.687 min) (8.869 min) maprotiline mianserin nortriptyline setiptiline trimipramine 10.5 7.1 9.7 7.8 7.7 0.53 0.80...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 30) doc

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 30) doc

Ngày tải lên : 15/12/2013, 12:15
... i) Since proteins are usually eluted within min, the eluate is not introduced into MS, but drained outside during this period After this time, the valve is switched to introduce clean eluate into ... nitro-group containing drugs, such as nitrazepam, nimetazepam, clonazepam and flunitrazepam, the nitro group is rapidly metabolized into an amino group (in the 7-position) after being absorbed into human ... benzodiazepine poisoning only are rare; simultaneous ingestion of other hypnotics or alcohol enhance the sedative and respiration-suppressing effects of benzodiazepines, resulting in deaths occasionally...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 31) ppt

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 31) ppt

Ngày tải lên : 15/12/2013, 12:15
... five unopened bottles containing the same tablets and a 1.5-L volume plastic bottle containing about a half volume of water were found By dental findings, the remains were found to be a 46-year-old ... column The peaks of bromisovalum and IS appeared at 3.77 and 6.22 min, respectively, without any interfering peak The calibration curve showed excellent linearity in the range of 0.1–10 µg/mL; recovery ... 5.1) contained in Wutt appears at 5.07 under the present HPLC conditions and thus can be an indicator of ingestion of Wutt In some analgesic-antipyretics, bromisovalum is also contained together...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 32) ppt

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 32) ppt

Ngày tải lên : 15/12/2013, 12:15
... of a hotel In her room, tablets of Vegetamin (a combined drug containing, phenobarbital, promethazine and Survived and fatal poisoning cases chlorpromazine) and one capsule of Insumin (flurazepam) ... Figure 6.2 Incidence of fatal barbiturate poisoning cases Since fatal cases due to Vegetamin® tablets containing phenobarbital are many, its incidence rate is also shown in this figure and Psychotropics ... promethazine and chlorpromazine were detected Drug concentrations in blood, the liver and kidney were: phenobarbital, 98.0, 106 and 105 µg/g; promethazine, 5.05, 38.2 and 6.92 µg/g; chlorpromazine,...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 33) doc

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 33) doc

Ngày tải lên : 15/12/2013, 12:15
... diphenyhydramine in blood and urine except for terolidine and triprolidine For the latter compounds, relatively intense molecular ions appear to be used for sensitive detection In the positive and negative ... analysis of chlorpheniramine and its metabolites in blood and urine [8] Chlorpheniramine is one of the most popular antihistaminics, and has been being used for over 50 years In this section, HPLC ... chlorpheniramine and its metabolites didemethylchlorpheniramine and demethylchlorpheniramine is described Reagents and their preparation • • • Chlorpheniramine maleate and brompheniramine maleate...
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Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 34) doc

Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 34) doc

Ngày tải lên : 15/12/2013, 12:15
... 2.3 shows the detection limits and colors of the spots observed under ultraviolet light and after spraying five kinds of reagents The screening by TLC is simple and rapid for unchanged drugs Reversed ... of urine or serum (plasma) is mixed well with 0.1 mL phosphoric acid and 0.5 mL of purified water and poured into an Oasis®MAX cartridge, which had been activated by passing mL methanol and mL ... heater After cooling to room temperature, a 1–3 µL aliquot of it is injected into HPLC vii Various concentrationsc of a target drug are spiked into blank specimens, and processed according to the above...
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