efficient inference through cascades
Tài liệu Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing pdf
Ngày tải lên :
18/02/2014, 08:20
... assays. However, the
same cells were efficiently killed by interferon-c. This effect was counter-
acted by the STAT3 oligodeoxynucleotide, which was found to efficiently
inhibit STAT1. Thus, although ... oligodeoxy-
nucleotide was added to a colon carcinoma cell line in which it induced cell
death as efficiently as the STAT3 inhibitor stattic. The hairpin STAT3
oligodeoxynucleotide co-localized with ... Efficient killing of SW480 colon carcinoma cells by a
signal transducer and activator of transcription...
- 11
- 558
- 0
Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
Ngày tải lên :
18/02/2014, 12:20
... Journal compilation ª 2008 FEBS 577
Reversible tetramerization of human TK1 to the high
catalytic efficient form is induced by pyrophosphate,
in addition to tripolyphosphates, or high enzyme
concentration
Birgitte ... coinciding with the increase in DNA synthesis, and
disappears during mitosis. The fluctuation of TK1 through the cell cycle is
important in providing a balanced supply of dTTP for DNA replication,
and ... as indicated by con-
cave Hofstee plots of v versus v ⁄ s (insets to the kinetic
plots), Hill coefficients < 1 and high K
0.5
values
(Table 1). All of the tetrameric forms showed approxi-
mately...
- 10
- 647
- 0
Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
Ngày tải lên :
19/02/2014, 17:20
... extracellular
Na
+
concentrations. The solid lines represent fits of the Hill equa-
tion with Hill coefficients of n ¼ 1.3 for the wild type GAT1 and
n ¼ 1 for the mutants (as used previously by Liu ... synthesized
proteins in the ER. If N-glycosylation is inhibited,
some glycoproteins fail to fold or assemble efficiently,
resulting in a prolonged retention in the ER and an
increased proteolytic breakdown ... GABA-
uptake activity. These indicate that the terminal
structure of the oligosaccharides facilitate efficient
GABA-uptake activity of the GABA transporter.
Defective N-glycosylation results in reduction
of...
- 14
- 654
- 0
Tài liệu Efficient Pattern Matching over Event Streams doc
Ngày tải lên :
19/02/2014, 18:20
... matching.
Figure 8(g) shows the benefits of merging in throughput
gain, defined as new throughput/old throughput. As can be
seen, merging offers remarkable overall throughput gains,
ranging from a factor of ... are needed in query processing.
The performance metric is throughput, i.e., the number of
events processed per second. In all experiments, throughput
was computed using a long stream that for each ... hence all achieve higher
throughput numbers. The advantage of our basic algorithm
over backtrack still holds, but with a smaller margin. On
the other hand, the difference in throughput between the
merging...
- 13
- 514
- 0
Tài liệu Báo cáo khoa học: Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units ppt
Ngày tải lên :
20/02/2014, 01:20
... ribozymes
that are structurally optimized and which, in addition to cleavage, catalyse
efficient RNA ligation. The most efficient variant ligated its appropriate
RNA substrate with a single turnover rate ... substrate
and the ribozyme seems to be most favourable for
an efficient reaction among the studied species.
HP–RJWTA7 is also an efficient endonuclease; it
cleaves the substrate S40F3F5 with k
obs
¼ ... engineered ribozyme for RNA sequence exchange
FEBS Journal 272 (2005) 4464–4474 ª 2005 FEBS 4465
Efficient RNA ligation by reverse-joined hairpin ribozymes
and engineering of twin ribozymes consisting...
- 11
- 481
- 0
Tài liệu Báo cáo khoa học: "Efficient Online Locality Sensitive Hashing via Reservoir Counting" ppt
Ngày tải lên :
20/02/2014, 04:20
... a
stream of positive and negative unit updates. The
sign of the sum of these updates is approximated
through a novel twist on Reservoir Sampling. When
computed explicitly this leads to an impractical
mechanism ... operations on a traditional 32-bit
counter. This leads to a tradeoff in space vs. time,
where a high-throughput streaming application that
is not concerned with online memory requirements
will not ... are handled similarly as when estimating the
number of accepts. These steps are found in lines 5
through 9 of Algorithm 1, and as seen in Fig. 2, this
can give a tight estimate.
Comparison Simulation...
- 6
- 469
- 0
Tài liệu Báo cáo khoa học: "Computationally Efficient M-Estimation of Log-Linear Structure Models∗" doc
Ngày tải lên :
20/02/2014, 12:20
... (and decoding under
them) is tractable only when the model’s indepen-
dence assumptions permit efficient inference proce-
dures. For example, in the original conditional ran-
dom fields (Lafferty et ... propose the use of a new loss
function that is computationally efficient and statis-
tically consistent (§2). Notably, repeated inference
is not required during estimation. This loss func-
tion ... 2003. Shallow parsing with conditional
random fields. In Proc. of HLT-NAACL.
A. Stolcke. 1995. An efficient probabilistic context-free pars-
ing algorithm that computes prefix probabilities. Computa-
tional...
- 8
- 286
- 0
Báo cáo khoa học: A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis doc
Ngày tải lên :
05/03/2014, 23:20
... concentrations were determined spectropho-
tometrically by absorbance at 280 nm, using an extinction
coefficient of 0.98 for a 1 mgÆmL
)1
solution [35]. Coenzyme
concentrations were also determined spectrophotometrically
using ... spectrophotome-
ter) due to the production of NAD(P)H at 340 nm, using a
millimolar extinction coefficient of 6.22 m
M
)1
Æcm
)1
. All rate
measurements were performed in triplicate and the results
shown ... inhibition of glutamate
dehydrogenase results from disruption of subunit
interactions necessary for efficient catalysis
Jaclyn Bailey
1
, Lakeila Powell
2
, Leander Sinanan
3
, Jacob Neal
3
, Ming...
- 12
- 544
- 0
Báo cáo khoa học: Efficient and targeted delivery of siRNA in vivo pdf
Ngày tải lên :
06/03/2014, 01:23
... efficiency
via efficient cytosolic release with high resistance to
serum and low cytotoxicity [129]. It was demonstrated
that ketalized linear polyethylenimine ⁄ siRNA poly-
plexes were efficiently ... silencing
because they were entrapped in the endosomes even
after efficiently entering cells [117]. Photostimulating
fluorescently labeled TAT efficiently released TAT–
siRNA conjugates from the endosome, ... potentially inefficient and time ⁄
labor-consuming modification processes (cost-effective
preparation). However, its highly anionic nature and
the macromolecular size of siRNA necessitates using
efficient...
- 14
- 599
- 0
Báo cáo khoa học: "Exploring Deterministic Constraints: From a Constrained English POS Tagger to an Efficient ILP Solution to Chinese Word Segmentation" ppt
Ngày tải lên :
07/03/2014, 18:20
... agree on the same tag. Both ways of de-
coding are purely rule-based and involve no proba-
bilistic inference. In favor of a higher precision, we
adopt the latter one in our experiments.
1055
Proceedings ... Computational Linguistics
Exploring Deterministic Constraints: From a Constrained English POS
Tagger to an Efficient ILP Solution to Chinese Word Segmentation
Qiuye Zhao Mitch Marcus
Dept. of Computer & ... deterministic
constraints can be learned from training exam-
ples, and these are useful in constraining prob-
abilistic inference. For tagging, learned con-
straints are directly used to constrain Viterbi
decoding. For...
- 9
- 425
- 0
Báo cáo khoa học: "Efficient Third-order Dependency Parsers" pdf
Ngày tải lên :
07/03/2014, 22:20
... ex-
pressive third-order factorizations while retaining
an efficient O(n
4
) runtime. In fact, our third-
order parsing algorithms are “optimally” efficient
in an asymptotic sense. Since each third-order ... “third-order”
in the sense that they can evaluate sub-
structures containing three dependencies,
and efficient in the sense that they re-
quire only O(n
4
) time. Importantly, our
new parsers can utilize ... has proven to be a very use-
ful syntactic formalism, due in no small part to the
development of efficient parsing algorithms (Eis-
ner, 2000; McDonald et al., 2005b; McDonald
and Pereira, 2006;...
- 11
- 322
- 0
Báo cáo khoa học: "Efficient Staggered Decoding for Sequence Labeling" pptx
Ngày tải lên :
07/03/2014, 22:20
... is the number of labels. Al-
though the Viterbi algorithm is generally efficient,
1
The first-order Markov assumption is made throughout
this paper, although our algorithm is applicable to higher-
order ... staggered
decoding efficiently performs the search step. For
this purpose, we can basically use the Viterbi algo-
rithm. In earlier iterations, the Viterbi algorithm is
indeed efficient because the ... Multi-level coarse-to-fine
PCFG parsing. In Proceedings of NAACL, pages
168–175.
Trevor Cohn. 2006. Efficient inference in large con-
ditional random fields. In Proceedings of ECML,
pages 606–613.
Michael...
- 10
- 332
- 0
Báo cáo khoa học: "An Efficient Indexer for Large N-Gram Corpora" docx
Ngày tải lên :
07/03/2014, 22:20
... hence efficient ac-
cessing of the N-gram frequencies becomes an is-
sue. Trivial methods such as linear or binary search
over the entire dataset in order to access a single
N-gram prove inefficient, ... Texas
Denton, TX 76203
rada@cs.unt.edu
Abstract
We introduce a new publicly available tool
that implements efficient indexing and re-
trieval of large N-gram datasets, such as the
Web1T 5-gram corpus. Our ... Introduction
The goal of statistical language modeling is to cap-
ture the properties of a language through a proba-
bility distribution so that the probabilities of word
sequences can be estimated....
- 6
- 320
- 0
- efficient method of moments
- efficient method of moments emm
- renewable and efficient electric power systems
- an efficient and flexible c toolkit
- guibased efficient medline search tool
- efficient unsupervised discovery of word categories
- efficient inference of crfs
- efficient handling of uncertainty
- efficient minimum error rate training