... applicants, a random sample of 15, 703 credit
applicants was selected for the study. The study then asked the CRAs to review the credit files of
the individuals in the sample and determine whether the credit ...
assessment ofthe degree of difficulty, andthe types of difficulties, with which each ofthe above
tasks was performed. The results ofthe pilot study, andthe next steps taken by the Commission
in ... obtaining a certification from the furnisher that the
information is complete and accurate, and then notifying the consumer ofthe reinsertion. 15 U.S.C. §
1681i(a) (5) .
59 . Disputed information is...
... values of 32 .5 °C and 46.6 °C for these
transitions. These T
m
values are nearly equal to those
of C-domain
+
( 35. 6 °C) and N-domain
+
(44.7 °C),
suggesting that the thermal unfolding transitions of
SIB1 ... proteolysis of L. pneumophila MIP allows
the separation of their N- and C-domains such that
the C-domain contains the C-terminal half ofthe a3
helix [23,24]. In addition, the C-domain of E. coli
FkpA ... consist of N- and C-domains, it would be informative
to construct the SIB1 FKBP22 variants containing
either one of these domains and compare their activities
and stabilities with those ofthe intact...
... determined by measuring the apparent K
m
value of
D
-ornithine at 25 , 50 , 100, 200 and 400 l
M
of the inhibitor.
For the measurement ofthe activity ofthe substrate
analogues, an HPLC and NMR-based method ... pyridoxal 5 ¢-phosphate via an azomethine link
between the formyl group ofthe c ofactor andthe amino
group of a protein residue. In contrast, the absence of
absorption maximum at 420 nm ofthe mutant ... expression vector under the control ofthe T7
promoter, and coexpression of oraE and oraS genes was
carried out in E. co li. Meanwhile, the extent of the
involvement of AdoCbl or PLP in the in vivo folding
process...
... common in people of northern
European descent. Their diagnosis is obvious when they are visible as glittering
particles upon the surface ofthe optic disc. However, in many patients they are
hidden ... fulminant papilledema.
Optic Disc Drusen
These are refractile deposits within the substance ofthe optic nerve head
(Fig. 29-13). They are unrelated to drusen ofthe retina, which occur in age-related ... beneath the surface, producing pseudo-papilledema. It is important to
recognize optic disc drusen to avoid an unnecessary evaluation for papilledema.
Chapter 029. DisordersoftheEye
(Part...
... Chapter 029. DisordersoftheEye
(Part 14)
Stroke
This occurs when interruption of blood supply from the posterior cerebral
artery to the visual cortex is prolonged. The only ... variety of genetic
diseases, such as myotonic dystrophy, neurofibromatosis type 2, and galactosemia.
Radiation therapy and glucocorticoid treatment can induce cataract as a side effect.
The cataracts ... viewing light reflected from the fundus with an ophthalmoscope or by
examining the dilated eye using the slit lamp.
The only treatment for cataract is surgical extraction ofthe opacified lens.
Over...
... Chapter 029. DisordersoftheEye
(Part 16)
Central Serous Chorioretinopathy
This primarily affects males between the ages of 20 and 50 . Leakage of
serous fluid from the choroid ... detachment ofthe retinal
pigment epithelium andthe neurosensory retina. These detachments produce acute
or chronic symptoms of metamorphopsia and blurred vision when the macula is
involved. They ... by administration of
panretinal laser photocoagulation at the appropriate point in the evolution ofthe
disease. For further discussion ofthe manifestations and management of diabetic
retinopathy,...
... Chapter 029. DisordersoftheEye
(Part 17)
Melanoma and Other Tumors
Melanoma is the most common primary tumor oftheeye (Fig. 29-18). It
causes photopsia, an enlarging scotoma, and ... atrophy of retrobulbar fat, or fracture ofthe orbital
floor. The position ofthe eyes within the orbits is measured using a Hertel
exophthalmometer, a hand-held instrument that records the position ... Ophthalmopathy
This is the leading cause of proptosis in adults (Chap. 3 35) . The proptosis is
often asymmetric and can even appear to be unilateral. Orbital inflammation and
engorgement ofthe extraocular...
... stretching and redundancy of
eyelid skin and subcutaneous fat (dermatochalasis). The extra weight of these
sagging tissues causes the lid to droop. Enlargement or deformation ofthe eyelid
from infection, ... weakness), or a family history of
ptosis should be sought. Fluctuating ptosis that worsens late in the day is typical of
myasthenia gravis.
Chapter 029. DisordersoftheEye
(Part 18)
Orbital ... older women. The signs are more subtle andthe diagnosis is frequently missed.
The combination of slight proptosis, diplopia, enlarged muscles, and an injected
eye is often mistaken for...
... "lazy" eye) in the deviated eye.
Chapter 029. DisordersoftheEye
(Part 19)
Myogenic Ptosis
The causes of myogenic ptosis include myasthenia gravis (Chap. 381) and a
number of rare myopathies ... primary gaze,
and then with the head turned and tilted in each direction. In the above example, a
cover test with the head turned to the right will maximize the fixation shift evoked
by the cover ... If theeye movements are full
and the ocular misalignment is equal in all directions of gaze (concomitant
deviation), the diagnosis is strabismus. In this condition, which affects about 1%
of...
... when the oculomotor nerve is
injured by trauma or compression (tumor, aneurysm). Miswiring of sprouting
fibers to the levator muscle andthe rectus muscles results in elevation ofthe eyelid ... from microvascular infarction ofthe nerve, somewhere along
its course from the brainstem to the orbit. Usually the patient complains of pain.
Diabetes, hypertension, and vascular disease are major ... the subarachnoid space the oculomotor nerve is vulnerable to aneurysm,
meningitis, tumor, infarction, and compression. In cerebral herniation the nerve
becomes trapped between the edge of the...
... impaired eye- hand coordination (optic ataxia), difficulty
initiating voluntary eye movements (ocular apraxia), and visuospatial
disorientation (simultanagnosia).
Chapter 029. DisordersoftheEye ... generally have the opposite effect: the eyes deviate conjugately away from the
irritative focus. Parietal lesions disrupt smooth pursuit of targets moving toward
the side ofthe lesion. Bilateral ... sclerosis are the most common
etiologies of brainstem abducens palsy.
After leaving the ventral pons, the abducens nerve runs forward along the
clivus to pierce the dura at the petrous apex,...