digital candidate gene approach digicga for identification of cancer genes
báo cáo khoa học: " Identification of Single Nucleotide Polymorphisms and analysis of Linkage Disequilibrium in sunflower elite inbred lines using the candidate gene approach" docx
Ngày tải lên :
12/08/2014, 05:20
... high-quality sequence data for the entire set of genotypes The IDs of the 28 candidate genes used for subsequent analyses are outlined in Table Briefly, four candidate genes, Glicolate Oxidase ... products of the expected sizes were detected for 40 regions (62.50%) and 28 of them (43.75%) yielded highquality sequence data The features and polymorphism indices of the 28 candidate genes used for ... and Burke [46] using only the subset of genes in common for both studies (Table 3) The θW average values were 0.0056 for the 19 Page of 14 (page number not for citation purposes) BMC Plant Biology...
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Tài liệu Fuzzy cluster analysis for identification of GENE regulating regions pptx
Ngày tải lên :
16/01/2014, 16:33
... D e p e D f p p p D h o GIG!IGrqeÔ2ofS2dhGIaG29GhI s53hfD 2Sa2292SIh255S hSfh5i2hfSSh3hIƠh! F e e F H o e D p D w D p e e D H w f H e xof}}SfhGIGhEfhGIG2SAclẳ fh9ÂGS~ ạ2ShIGhSfhÂÂ ... F p b H o D e b X p F D b quI2SdGSI3!GIfhdHIafhGD i}Ihofh H e p H D F y e m p o p f F p o D F w e p F 2hfSGS3hÂ}ofr3hIƠfrẩHfrIhh2Ihu H f H H D e p H eQ H F p p F u F ... E2SfhgÂi ~~Ă@ fhSSScAfha5BSÂhIGhhGp e D f F o D ã D f m D w e h D f m o D H k ! ofhS9}" G Wf}hdG fr#aG F p ` IG2ffSaG2GhIdI2SIh2SS!ShSfhdw H D o D e D e p e...
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Báo cáo khoa học: "A machine-learning approach to the identification of WH gaps" doc
Ngày tải lên :
24/03/2014, 03:20
... frame of every verb and preposition in the corpus, which is a prerequisite for the methods mentioned above The only previous work we are aware of which addresses the task of identification of WH ... Mouton, The Hague for other systems to which we can compare them We take this level of success as an indication of the feasibility of our data-driven, modular approach Additionally, our approach has ... a path could be represented as one of a finite number of classes Therefore, we treat the search downward through the phrase-structure tree for the location of a gap as a Markov process That is,...
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Báo cáo y học: "Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes" pdf
Ngày tải lên :
12/08/2014, 11:23
... the NP Our analysis of NP-specific genes also identified for the first time three novel genes (SNAP25, CDH2 and SOSTDC1) not previously reported in the IVD All three of these genes demonstrated ... accurate For this reason, genes of interest were further verified using qRT-PCR Following comparison of NP/AF&AC cell gene expression from bovine microarrays, six potential NP marker genes were ... cells (P < 0.05) qRT-PCR validation of cell-specific marker genes in human samples Gene expression in normal samples Analysis of expression of traditional marker genes in human normal IVD samples...
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Báo cáo sinh học: "An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies" pot
Ngày tải lên :
12/08/2014, 17:20
... effector, if its gene was found in the same locus as genes of the corresponding pathway, or if it shared a DNA regulatory motif with these genes As such functional data are not available for the enzyme ... Benchmark datasets Generated data We generated two families of sequences of 190 amino acid in length following a naïve random evolutionary model A random sequence of 190 amino acids was generated using ... correction for the background distribution of the mutual information is performed Instead of using shuffling, which is computationally inefficient, we pre-calculate the mean and the variance for any...
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Evolutionary divide and conquer strategy for identification of structural systems and moving forces
Ngày tải lên :
11/09/2015, 10:00
... multiple moving forces. Figure 5.2 A layout of moving force identification procedure. Figure 5.3 Identified moving forces for 5% noise: (a) force 1; (b) force 2; (c) total force; simulated force: continuous ... Substructural Identification Strategy 73 3.2 Numerical Studies 76 3.2.1 Identification of 20-DOF System without Input Forces 77 3.2.2 Identification of 100-DOF System without Input Forces 79 ... DIVIDE-AND-CONQUER STRATEGY FOR IDENTIFICATION OF STRUCTURAL SYSTEMS AND MOVING FORCES TRINH NGOC THANH B.Eng (HCMUT) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CIVIL ENGINEERING...
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Using computational approach in understanding gene regulatory networks for antimicrobial peptide coding genes
Ngày tải lên :
14/09/2015, 09:05
... that the outcome will be a set of genes and/or new AMP genes themselves Thus, this approach facilitates unfolding the relationship of AMP genes with other genes of the same pathway and helps us ... promoter data for (Chapter 7) a) detection of new co-regulated genes, and b) deciphering parts of gene networks of which AMP genes are members 1.4 Contribution of this thesis AMP-coding genes and ... complement homology based gene identification This approach also facilitates in unfolding of possible new association of genes with other genes (in terms of co-regulation) of the same pathway and...
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Proteomics approach on the identification of virulence factors of enteropathogenic and enterohemorrhagic escherichia coli (EPEC and EHEC) and further characterization of two effectors espb and nlei
Ngày tải lên :
15/09/2015, 17:09
... cluster of perA, perB, perC genes at the downstream of the bfp gene cluster in the same EAF plasmid These perABC genes encode transcriptional activators that positively regulate several genes in ... pathogenesis independent of Stxs activity To expound the difference and similarity of EPEC and EHEC, their pathogenesis and virulence factors will be separately discussed below I.2.1 EPEC pathogenesis ... indicated that the structure of BFP and the intact function of BFPs are required for the full virulence of EPEC (Bieber et al., 1998) I.2.1.3 EAF plasmids The genes coding for BFP of EPEC are located...
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Application of genetic markers for identification of halophila members and genetic variation of halophila ovalis from western pacific to eastern indian ocean
Ngày tải lên :
20/05/2016, 16:28
... applications of genetic markers in seagrass Today, genetic markers are widely applied for the species identification as well as genetic diversity, population structure of the species For plastid ... center of seagrass biodiversity Sulfur-containing compounds and heavy metal accumulation of seagrass Aims of this thesis Reference CHAPTER 2: Variability of leaf morphology and marker genes of members ... Application of genetic markers for identification of Halophila members and genetic variation of Halophila ovalis from Western Pacific to Eastern Indian...
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Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt
Ngày tải lên :
16/02/2014, 08:20
... access to information on glycogenes In the GGDB, the information on each glycogene is stored in XML format: gene names (gene symbols), enzyme names, DNA sequences, tissue distribution (gene expression), ... stage in this process Establishment of a qPCR method for the measurement of 186 human glycogenes We began by performing a comprehensive study of human glycogenes, which encode proteins involved ... clones of glycogenes were used as reference templates for qPCR analysis in the experiments To improve the throughput of qPCR measurements, we built a customized qPCR array platform for glycogene...
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gene therapy in the treatment of cancer
Ngày tải lên :
10/04/2014, 22:11
... Thus, numerous genes can be implicated in oncogenesis, or the development of a malignant tumor These include oncogenes, or the activation of growth-promoting genes, and tumor suppressor genes, or ... as for an oncogene or growth factor, then approaches at gene deletion or regulation of gene expression could be employed Augmentation of Tumor Suppressor Genes Tumor suppressor genes are a genetically ... targets of antisense gene therapy in cancer are overexpressed oncogenes that play a role in pathogenesis Numerous oncogenes have been targeted for antisense gene therapy They include c-fos for brain...
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Báo cáo sinh học: "Review of the 25th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer (now the Society for Immunotherapy of Cancer)" potx
Ngày tải lên :
18/06/2014, 19:20
... Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) provided a scientific platform for ~500 attendees ... Page of Author details Society for Immunotherapy of Cancer, Milwaukee, WI, USA 2University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA 3Department of Cutaneous Oncology, Moffitt Cancer ... possibility of correcting the impaired function of human TILs While the identification of human tumor-specific Ags has allowed the development of numerous cancer vaccine strategies, these approaches...
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báo cáo hóa học:" Review of the 25th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer (now the Society for Immunotherapy of Cancer)" pot
Ngày tải lên :
20/06/2014, 03:20
... Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) provided a scientific platform for ~500 attendees ... Page of Author details Society for Immunotherapy of Cancer, Milwaukee, WI, USA 2University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA 3Department of Cutaneous Oncology, Moffitt Cancer ... possibility of correcting the impaired function of human TILs While the identification of human tumor-specific Ags has allowed the development of numerous cancer vaccine strategies, these approaches...
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Báo cáo y học: " Identification of fusion genes in breast cancer by paired-end RNA-sequencing" potx
Ngày tải lên :
09/08/2014, 22:23
... gene identification by paired-end RNAsequencing (a) Identification of fusion gene candidates through selection of paired-end reads, the ends of which align to two different and non-adjacent genes ... involvement of known oncogenic partner genes, exclusive expression of the partner genes as a fusion gene and RNAi-mediated knock-down studies Finally, even if some of the fusion genes are not ... junction Expression of fusion genes and wild-type parts of the fused genes was calculated as uniquely mapped reads per kilobase of gene sequence per million mapped reads (RPKM) Fusion gene expression...
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báo cáo khoa học: " Identification of imprinted genes subject to parent-of-origin specific expression in Arabidopsis thaliana seeds" potx
Ngày tải lên :
11/08/2014, 11:21
... expressed) Hence, ‘next generation’ sequencing studies are now being employed to identify putative imprinted genes [23,24] An indirect approach for the identification of novel imprinted genes has been ... endosperm [17] The choice of transcript profiling platform is an important consideration for identification of novel imprinted genes Microarrays are dependent on genes being expressed at a level sufficient ... profiling, we have developed a gene- identifying bioinformatic software program, GenFrag, which can determine the identity of genes displaying parent -of- origin specific cDNA-AFLP expression profiles...
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báo cáo khoa học: " Identification of flowering genes in strawberry, a perennial SD plant" potx
Ngày tải lên :
12/08/2014, 03:21
... breeding of strawberry and other soft fruit and fruit species of Rosaceae family For comprehensive identification of candidate genes of the strawberry flowering pathways, we searched homologs for ... putative homologous genes identified from our EST collection In general, candidate genes for all major pathways were identified In addition, 118 Arabidopsis flowering time genes were used as a ... Additional file 2) Identification of floral integrator genes in Fragaria Sequencing of our EST collections did not reveal any homologs for the floral integrator or identity genes such as FT, SOC1,...
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báo cáo khoa học: " Complete plastid genome sequences suggest strong selection for retention of photosynthetic genes in the parasitic plant genus Cuscuta" ppt
Ngày tải lên :
12/08/2014, 05:20
... [65] for each gene and for classes of genes that together encode subunits of larger proteins ATP synthase genes, genes, 4344 aligned characters (atp); cytochrome b6/f complex subunits, genes, ... plastid genes directly involved in photosynthesis within the chloroplast, including all atp genes, all pet genes, rbcL, and all psa and psb genes, with the exception of psaI This gene is one of the ... the size of that in normal angiosperms due to ubiquitous gene loss, including all photosynthetic and photorespiratory genes, some ribosomal protein genes, many tRNA genes, and genes for plastid-encoded...
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Báo cáo y học: "Large-scale identification of human genes implicated in epidermal barrier function" ppsx
Ngày tải lên :
14/08/2014, 07:21
... Representative sample of genes with the highest number of ORESTES No of ORESTES Gene symbol No of UniGene ESTs Full name (alias) Ubiquitously expressed genes with a high number of UniGene ESTs 142 RPS8 ... Biology 2007, Figure Expression profile of newly identified genes Expression profile of newly identified genes PCR experiments were performed with a commercial panel of cDNAs from 16 human tissues ... Figure of new human lipase Analysis (see following page) genes Analysis of new human lipase genes (a) Schematic representation of the lipase gene cluster on chromosome 10q23.31 Six lipase genes, ...
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