concepts in immunology and vaccinology
Tài liệu Human Breast Milk: Current Concepts of Immunology and Infectious Diseases pptx
Ngày tải lên :
22/02/2014, 05:20
... blocking adsorption/penetration of viruses and adhesion of bacteria, contributing to intestinal cell growth and repair (maintaining an effective barrier), and decreasing production of interleukins-1, ... and secreted proteins that stimulate, inhibit, and regulate the immune response such as cytokines and interferons; (3) humoral immunity including B-cells, plasma cells, and immunoglobulins; and ... few immunoglobulin-producing intestinal plasma cells present in the first week or two of life.78 After to weeks of age, the number of IgMand IgA-producing cells in the intestine increase From approximately...
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New Concepts in Diabetes and Its Treatment - part 1 ppt
Ngày tải lên :
09/08/2014, 15:20
... cleaved into the so-called connecting peptide (C-peptide) and the insulin molecule, composed of two peptide chains containing 51 amino acid residues Both insulin and C-peptide are packaged in the ... glucose production in the postprandial period Assessment of Insulin Secretion Fasting Insulin Level The fasting insulin level (normally between and 15 U/ml) may reflect the insulin secretory capacity ... in subjects with high insulin sensitivity (lean and/ or trained subjects) and elevated (?15 U/ml) in insulin-resistant subjects It should be pointed out that an apparent normal insulin level in...
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New Concepts in Diabetes and Its Treatment - part 2 docx
Ngày tải lên :
09/08/2014, 15:20
... PKB>protein kinase B; PKC( , )>protein kinase C, forms and ; PKC>protein kinase C; PLC> phospholipase C; Shc>protein containing a single SH2 domain, substrate of insulin receptor tyrosine kinase; ... protein kinase; PC-1>an ecto-protein kinase probably interfering with insulin receptor tyrosine kinase; PI3-K>phosphatidylinositol-3 kinase; PIP2>phosphatidylinositol-4,5-P; PKA>protein kinase ... protein; Gs and Gi> stimulatory and inhibitory G proteins; Ins>insulin receptor; IP3>inositol-1,4,5trisphosphate; IRS1>insulin receptor substrate-1; IRS2>insulin receptor substrate-2; M>muscarinic...
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New Concepts in Diabetes and Its Treatment - part 3 docx
Ngày tải lên :
09/08/2014, 15:20
... insulin, obtained by adding the protein protamine to insulin and adjusting the pH (c) The long-acting insulin preparations include the ultralente insulin, obtained by modifying, during the preparation, ... regular insulin as well as the semilente insulin which is a suspension of insulin and zinc in acetate buffer (with formation of zinc-insulin crystals) (b) The intermediate-acting insulins comprise ... of zinc and insulin to produce larger zinc-insulin crystals (the larger the crystals, the slower the release of the injected insulin) as well as the protamine-zinc insulin obtained by adding...
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New Concepts in Diabetes and Its Treatment - part 4 ppsx
Ngày tải lên :
09/08/2014, 15:20
... Yki-Jarvinen H: One year’s response to evening insulin therapy in non-insulin-dependent diabetes J Intern Med 1992;231:253–260 Strowing S, Raskin P: Insulin treatment and patient management; in Rifkin ... immunogenicity of insulin Belfiore/Iannello 86 Table Factors in uencing the formation of insulin antibodies Insulin species (human insulin is less immunogenic than animal insulins) Insulin purity (monocomponent ... Altered Insulin Responses Conditions of altered insulin responses include: (a) insulin resistance linked to occult infections; (b) iatrogenic hypoglycemia or factitious inten- Insulin Treatment in...
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New Concepts in Diabetes and Its Treatment - part 5 pdf
Ngày tải lên :
09/08/2014, 15:20
... or insulinoma Functional hypersecretion of -cells Autoantibodies to insulin Autoantibodies to insulin receptors Sepsis Insulin or insulin-releasing drugs (sulfonylureas, pentamidine, quinine) ... simultaneous determinations every 4–6 h of glycemia, insulinemia and C-peptide during fasting periods of 24, 48 and 72 h In insulinoma, glycemia falls while C-peptide and insulinemia remain near-unmodified ... cause insulin resistant diabetes, can in some patients act as insulin-like factors); (e) ectopic insulin secretion (2) Sepsis (cytokines associated to endotoxinemia increase insulin release) (3) Insulin...
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New Concepts in Diabetes and Its Treatment - part 6 pot
Ngày tải lên :
09/08/2014, 15:20
... insulin resistance and/ or hyperinsulinemia Since insulin resistance is also a mechanism involved in the pathogenesis of type diabetes, insulin resistance may also contribute to BP elevation in ... retinopathy Retinopathy Inside the retina (background retinopathy) Not vision-threatening In front of the retina (neovascularizations) Simple Vision-threatening Maculopathy Proliferative retinopathy ... extent caused by disturbances in the diabetic metabolism in pregnancy Since the risk for developing diabetic retinopathy during pregnancy increases with increasing duration of diabetes, diabetic...
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New Concepts in Diabetes and Its Treatment - part 7 pdf
Ngày tải lên :
09/08/2014, 15:20
... Lipoprotein Metabolism Hepatic production of VLDL is regulated by insulin (and the anti-insulin hormones) at different sites In fact, insulin, by inhibiting lipolysis at adipose tissue level, refrains ... double-blinded without being long term and some long term and randomized without being blinded All these trials generally showed a reduction or a stabilization in microalbuminuria In a recent randomized ... coexisting visceral obesity and insulin resistance Fasting TG and visceral obesity appear to independently predict mortality from CAD in glucose-intolerant and diabetic subjects The predominance...
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New Concepts in Diabetes and Its Treatment - part 9 pdf
Ngày tải lên :
09/08/2014, 15:20
... Multifactorial Intervention in Type Diabetes mellitus 231 Insulin Insulin treatment can be given as monotherapy or as combination therapy with insulin and oral hypoglycaemic agents From studies comparing ... studies comparing several insulin regimens, bedtime NPH insulin in combination with metformin twice daily and self-adjustment of insulin dose based on patients’ own fasting blood glucose measurements ... be an easy and safe way of obtaining optimal glycaemic control This combined insulin and metformin treatment regimen is associated with less weight gain than monotherapy with insulin Whereas...
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Current concepts in pediatric and adult congenital cardiac critical care
Ngày tải lên :
14/12/2015, 20:33
... the care of pediatric and adult congenital cardiac patients Learning Objectives • Gain an understanding of the latest developments and techniques in neonatal, pediatric, and adult congenital ... pulmonary hypertension and its management • Learn the advances in electrophysiology and pacemakers • Understand the indications and best practices in extracorporeal support in pediatric critically ... in the activity Nursing Continuing Education Credits The NewYork-Presbyterian Hospital School of Continuing Education for Nurses is an approved provider of continuing nursing education by the...
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The concepts of art and poetry in Emmanuel Levinas’s writings
Ngày tải lên :
01/11/2013, 10:20
... consciousness is stopped in its tracks by an image and cannot get round behind it to an originating intention that would transform it into a meaning (a symbol or stand -in) Thus a painting is not, pace ... visits in Hades, life dissolves into a shadow’ (ti 112).) Levinas figures this experience of exteriority in terms of insomnia and the interminability of the night, as well as in terms of certain kinds ... entails in the metaphor of grasping things and laying them open to view (cp 3) The image implies a reversal of power that turns the subject into a being ‘among things’, wandering ‘among things as...
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Recent Advances in Immunology to Target Cancer, Inflammation and Infections Edited by Jagat R. Kanwar ppt
Ngày tải lên :
07/03/2014, 20:20
... functioning and also for determining the optimum immunization. This chapter provided by Dr. De Castro Alexandre is interesting in explaining the simulations that found the dynamic behaviourandtheantigendependencyforBcellmemory.Itisfollowedbythereview ... C and minor antigens E, F, and G, while MHC class II consists of HLA-DM, -DO, -DP, DQ, and -DR Using a polyclonal stain specific for HLA-A, -B and -C heavy chains in formalin-fixed, paraffin-embedded ... blots may not work for staining since staining requires fixation, which can change the confirmation of the cytokine protein, thereby preventing antibody binding (Sachdeva and Asthana 2007) Most...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
Ngày tải lên :
15/03/2014, 23:20
... heparanase in human cancer by focusing on head and neck carcinoma and multiple myeloma as examples of solid and hematological malignancies Heparanase in head and neck carcinoma: signaling in motion ... protein-coding genes contain introns that are removed in the nucleus by RNA splicing and are often alternatively spliced Alternative splicing increases the coding capacity of the genome, generating ... enriched in lung carcinoma and chronic myeloid leukemia compared with control tissue and cells In this splice variant, 144 bp of intron are joined with exon 4, resulting in a 169-amino-acids protein...
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Coronary Artery Disease – Current Concepts in Epidemiology, Pathophysiology, Diagnostics and Treatment Edited by David Gaze pptx
Ngày tải lên :
17/03/2014, 00:20
... These findings are cause for concern, indicating that decades of progress in reducing deaths from CAD appear to be stalling Changes in lifestyle factors in the young (increasing obesity and sedentary ... age and sex, in England in 2008 Chronic stable angina 4.1 Defining chronic stable angina The evaluation of epidemiologic data concerning chronic stable angina is more challenging than assessing ... mortality statistics and suggest that in Scotland the incidence of AMI has decreased by about 25% between 2000 and 2009 in both men and women Thus considering all ages in Scotland in 2006, approximately...
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nanophysics and nanotechnology an introduction to modern concepts in nanoscience
Ngày tải lên :
29/05/2014, 18:17
... realized in mechanical rather than electrical terms The linear engines, myosin and kinesin, move along protein polymers, (actin and microtubules, respectively), in quantized steps, using up a ... the beginning of the 21st century, with a wealth of knowledge in scientific and engineering disciplines, and really rapid ongoing advances, especially in areas of nanotechnology, robotics, and biotechnology, ... 3.2.2 Linear Engines on Tracks The spring and ratchet systems, structurally ill-defined but clearly electrostatic in mechanism, contrast with well defined linear and rotary engines, which move in...
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core concepts in supramolecular chemistry and nanochemistry, 2007, p.321
Ngày tải lên :
04/06/2014, 15:14
... chemistry, including anion binding and sensing, and crystal engineering studies using strong and weak hydrogen bonds In 1998, he was awarded the Royal Society of Chemistry Meldola Medal and was ... to this match in size and shape and bind via complementary binding sites within this pocket or cleft In general, in order to achieve strong, selective binding, the binding site of the host must ... born in Essex (a true Essex boy!), UK in 1978 He obtained his B.Sc at the University of the West of England, Bristol in 1999, where he developed an interest in inorganic chemistry and coordination...
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dorsey lopes - important concepts in signal processing, image processing and data compression
Ngày tải lên :
05/06/2014, 11:40
... successfully in fighter aircraft, with applications including: setting radio frequencies, commanding an autopilot system, setting steer-point coordinates and weapons release parameters, and controlling ... differences The level set method was initially proposed to track moving interfaces by Osher and Sethian in 1988 and has spread across various imaging domains in the late nineties It can be used to efficiently ... coarse-scale image features to finer scales using isointensity information Lindeberg studied the problem of linking local extrema and saddle points over scales, and proposed an image representation...
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