... strongly influenced by the presence, intensity and type of farming activity inthe surrounding watershed We evaluated this hy- pothesis by examining the colonisation of ceramic sub- strates incubated ... years by the Que ´bec Ministry ofthe Environment (MENV) (Painchaud, 1997) We selected the sites according to the availability of physico-chemical data and on the ba- sis of land use information ... substrates Since the purpose ofthe experiment was to evaluate the use of algae as an indicator of farming activity, the use of artifi- cial substrates eliminated any potential effect of differ-...
... development of long lateral roots could lean inthe same way On the other hand, the influence of soil properties may be overriding on the changes of root architecture The influence of physical ... Statistical studies of these ture are data allow the determination of elongation laws and branching patterns They may then be integrated into a deterministic three-dimensional model (Pages and Aries, ... detail in this volume, is roof segment based In our method, synthetic parameters of root growth and architecin specified in terms of growing time for each order (number of axis, time of emergence,...
... explained inthe following way The chance of finding a seed-match andof producing a local alignment of significant similarity rises with the length ofthe fragment Longer fragments, then, are ... points (Figure S3 in Additional file 1) Therefore, requiring a minimum distance in bitscore between the best and second best hit is Page of 15 very effective in removing most ofthe remaining ... location ofthe human and chimp hits for each read is verified by using liftover [50] to map the coordinates ofthe human hit to the chimpanzee genome andthe coordinate ofthe chimpanzee hit to the...
... They are reported to occur in between in 6000 andin 16,000 live births They can occur anywhere inthe body, but 75% involve the posterior neck, 20% the axilla and 1% the mediastinum, groin and ... definitively identified postoperatively We offer an overview ofthe role of imaging and suggest that both the local anatomy andthe organisation ofthe cystic structure be borne in mind inthe ... Isolated intrathoracic cystic hygroma is a rare finding; less than 1% of all cystic hygromas are purely mediastinal in origin Inthe majority of cases, these are located inthe anterior mediastinum and...
... treatment andthe presence of p53 An ontology analysisof these 54 proteins revealed that they were mainly involved inthe regulation of cellular growth and proliferation Downstream validation analysis ... hypoxia inthe presence and absence of p53 4.6 A protein expression and interaction network of proteins, involved 80 in cellular growth, proliferation and cell cycle, inthe absence of p53 under ... tetramerization of p53 which is the most active DNA binding form Other kinases, such as casein kinase I and II, protein kinase A, 38 CDK7, DNA-activated protein kinase, and Jun-NH2 kinase (JNK),...
... parallel to the introduction of New Public Management by the Thatcher-government inthe United Kingdom and to the Reinventing Government reforms initiated by the Clinton-Gore administration inthe United ... form of public accountability Increasingly, the results of inspections, assessments and benchmarks are put on the internet For example, inThe Netherlands, as inthe UK (Pollitt 2003: 41-45), the ... part of their tasks to more or less independent bodies 25 and institutions In due course, the public organisations andthe executive public servants andthe end ofthe chain have the task of spending...
... Conclusions, including the results ofthe November 2001 Workshop Management Framework - Introd uced Marine Pests Management capabilities and approaches APEC andthe MRCWG have a role in liaising with ... Within APEC little is known on the introduction of marine pests Little practical information on measures to prevent introductions Lack of knowledge in what individual countries are doing ... NACA to enhance the effectiveness of existing instruments within APEC Institutional arrangements for managing the marine environment is fragmented in most economies Baseline surveys to identify...
... useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy ofthe vaccine strain administered Vol 45 / No RR-4 MMWR andthe vaccinee’s age at the time of vaccination ... resurgence inthe incidence of TB occurred inthe United States and included increases inthe number of TB cases among adults and children and outbreaks of multidrug-resistant TB (MDR-TB) involving ... Control and Prevention The role of BCG vaccine inthe prevention and control of tuberculosis inthe United States: a joint statement by the Advisory Council for the Elimination of Tuberculosis and the...
... basis points ofthe 11 basis-point decline inthe average expense ratio of funds of funds over the period (labeled in Figure 13 as “Fall in expense ratios of individual funds”) By definition, the ... inflation by taking the fee breakpoints available in 2010 and multiplying by the Consumer Price Index in December 2000 and dividing by the Consumer Price Index in December 2010 The front-end ... endowments, and other institutional investors investing for their own accounts, rather than on behalf of retail investors Stock Funds The average fees and expenses paid by stock fund investors declined...
... declined in 2011 owing to declines inthe expense ratios of individual funds, an increase inthe demand for index funds, and a continuing shift by investors in both actively managed and index ... percentage ofthe assets that the financial professional manages for an investor, rather than as a percent ofthe dollars initially invested Over time, brokers and other financial professionals ... collects the 12b-1 fee, passing the bulk of it to the financial professionals serving fund investors Alternatively, investors may pay the professional an asset-based fee directly In such cases, the...
... On the other hand, inthe far Northeast, along the Mekong River, over 2030 mm is received annually Variation inthe average amount of rainfall is therefore notable inthe Northeast During the ... in Thailand, andthe University of Helsinki This study was also a joint undertaking inthe long series of academic collaboration between the universities of Kasetsart and Helsinki 1.2 Scope and ... Research Institute of Thailand (RRIT) andthe Office ofthe Rubber Replanting Aid Fund (ORRAF) The RRIT works under the Department of Agriculture (Ministry of Agriculture and Cooperatives), and its...
... ONE is the INTRODUCTION This includes an outline ofthe CONTEXT and main themes, the motivation and purpose ofthe study - the why and how PART TWO is THE REASEARCH - METHODOLOGY and FINDINGS PART ... component inthe integration process: The first step towards the integration of refugees must be to identify and help with their most pressing needs Finding and settling them into safe and appropriate ... section is THE RESEARCH; this is also presented in two sections The first part provides an outline ofthe METHOLOGY andthe following section provides an analysisofthe FINDINGS from the interviews...
... (disordered inthe ligand-free state in YbgJ) Inthe absence ofthe ligand, the lid part is separated from the active site, which leads to a more open active site Upon the binding of ligand inthe acyl-enzyme ... conformations ofthe regions at 100-105 and 303-309 aa inthe N form, and we investigated the following points First, these areas are not involved in any contacts with other molecules in crystals in all the ... basis of their crystal structures andthe conserved amino acid residues (aa) of their active sites, these glutaminases are classified into a large group of bacterial penicillin-binding proteins and...
... upon the piazza with blocks and other playthings, and finally had gone into the house, leaving all the things on the floor ofthe piazza, instead of putting them away in their places, as they ... had been enjoined upon them as, for example, when they left the door open in coming in or going out, inthe winter; or interrupted their mother when she was reading, instead of standing quietly ... in accomplishing the result, andin a manner altogether more agreeable to both parties The third will make the work of forming the habit of obedience on the part ofthe mother, andof acquiring...
... shown in Fig 1B, the distance between the two termini ofthe inserted Ca2+-binding sites inthe model structure ofthe EF-hand of STIM1 is within ˚ 15 A Accordingly, a total of six glycine linkers ... Ca2+-coordinating loop positions and was introduced to perturb the Ca2+-binding ability ofthe grafted EF-hand of STIM1 (B) Modelled structure ofthe engineered protein with the grafted EF-hand Ca2+-binding ... EF-hand motif in STIM1 is occupied by Ca2+ Removing the proposed Ca2+-coordinating residues in positions andofthe EF-hand motif significantly compromised the metal-binding capability ofthe engineered...
... timescale in both ofthe free modules Thus, these loops are strong candidates for binding sites of other complement and ⁄ or regulatory proteins The large insertion between E and F strands in C1r ... neighboring domains offers a new way to understand the regulation of multidomain proteins andchallengesthe generally accepted view that domains are independent functional and folding units Therefore, ... of a tyrosine in strand C of CCP4 in place of an asparagine in C1r CCP2 (N379), and based on the results ofthe present perturbation study, we suggest that the inter-CCP flexibility in C1r is...
... ung th in vitro, thấy quercetin làm thoái giáng đột biến p53 - protein, làm ngừng chu kỳ tế bào giai đoạn G1 , ức chế tyrosin - kinase, ngăn chặn hoạt tính protein - ras In vitro, quercetin ức ... Curcumin có nhiều ảnh hởng đến sinh lý bệnh học tế bào ung th: in vitro, curcumin làm ngừng chu kỳ tế bào u, thúc đẩy chết theo chơng trình (apoptosis) Tuy nghiên cứu hạn chế, nhng thấy curcumin ... bào khác nhau, thấy quercetin làm tăng hiệu lực điều trị cisplatin, adriamycin, busulfan, cyclophosphamid làm tế bào ung th giảm đề kháng với gemcitabin topotecan Bromelain Là hỗn hợp protease chứa...
... Solving the Model 11 Solving the Model 12 Solving the Model Define and predict the long term benefits 13 Solving the Model Define and predict the long term benefits Asses the risks 14 Solving the ... control, fertilizing, pruning and thinning, fire and pest protection Inflows:wood; commercial thinning, final harvest non-wood; flora gathering, recreation, land renewal Required rate of return ... the Model Define and predict the long term benefits Asses the risks Estimate the cash flows 15 Solving the Model Define and predict the long term benefits Asses the risks Estimate the cash flows...
... group inthe a position ofthe fatty acyl residues The signals that correspond to the resonance ofthe methine proton ofthe a carbon (d) and that ofthe carbon bearing the methyl group near the ... unknown, andthe specific roles ofthe various members ofthe DIM family, e.g DIM A and DIM B, in these functions have never been investigated The recent developments in our understanding ofthe biosynthetic ... obtained for four mice, indicating that fewer than 50 bacteria ofthe PMM56 mutant strain were present inthe spleen of these mice For the determination ofthe number of PMM56 bacteria present in...