...
Artificial
UV Radiation
and
Skin Cancer
WORLD HEALTH ORGANIZATION
International Agency for Research on Cancer
IARC 2006
Exposure to Artificial
UV Radiation and
Skin Cancer
IARC
2006
ISBN 92 832 ... adolescents.
Skin type
Few studies have analysed specifically the use of
indoor tanning facilities as a function of skin type.
Since most studies have been conducted primari-
ly in relation to skincancer ... valid animal model of human melanoma or
other skin cancers exists, evidence of an associ-
ation between indoor tanning facility exposure
and skincancer must be sought predominantly
from epidemiological...
... provider trained in screening for skin cancers.
The general population not at increased risk of skincancer
There is at this time no evidence for or against skincancer screening of the general ... traits have a higher than average risk of developing skin cancer.
References
1. US Preventive Services Task Force. Screening for skin cancer: recommendations and
rationale. Am J Prev Med. ... and skincancer awareness in outdoor
workers in Israel. Cancer Causes Control. 2000;11(6):513-21.
6. Berwick M, Begg CB, Fine JA, Roush GC, Barnhill RL. Screening for cutaneous melanoma
by skin...
... per 100,000
persons (10).
Burden of Skin Cancer
Skincancer is the most common type of cancer in the United
States (11). The two most common kinds of skincancer —
basal cell carcinoma and squamous ... 1
Burden of SkinCancer 2
Risk Factors for SkinCancer 2
Protective Behaviors 4
Concerns Regarding Promoting Protection
from UV Radiation 6
Guidelines for School Programs To Prevent SkinCancer 6
Schools ... attitudes, and behavioral skills they need
to prevent skin cancer.
4. Involve family members in skincancer prevention
efforts.
5. Include skincancer prevention with professional
development of...
... Stop Cervical Cancer: www.cervicalcanceraction.
org/home/home.php
International Union Against Cancer: www.uicc.org
American Joint Committee on Cancer: www.cancerstaging.
org/
National Cancer Institute: ... and
Obstetrics.
KEYWORDS
FIGO;
Gynecological cancer
staging system;
History
1. Introduction
Cancer staging is one of the fundamental activities in oncology
and is of pivotal importance to the modern management of
cancer patients. ... developments in cancer
staging. Cancer Prev Control 1998;2:262–8.
[3] Pecorelli S, Ngan HYS, Hacker NF, editors. Staging Classifica-
tions and Clinical Practice Guidelines for G ynaecological
Cancers....
... in select nasopharynx and thyroid cancers.
A. Upper Aerodigestive Tract Sites
The majority of tumors arising in the head and neck (other than non-
melanoma skin cancers) arise from the squamous ... Committee on Cancer (AJCC) Tumor
Staging by Site 16
A. Oral Cavity 16
B. Oropharynx 16
C. Larynx 17
D. Hypopharynx 19
E. Nasal Cavity and Paranasal Sinuses 20
F. Salivary Glands 21
G. Neck Staging ... invades the skin, mandible, ear canal, and/or facial
nerve.
T4b Tumor invades the skull base and/or pterygoid plates and/or
encases the carotid artery.
G. Neck Staging Under the TNM Staging System...
...
predict, and many skincancer experts consider them a type of squamous cell skincancer and
treat them as such.
Less common types of skincancer
Along with melanoma and keratinocyte cancers, there ... about basal and
squamous cell skin cancers?
Cancer of the skin (including melanoma and basal and squamous cell skin cancers) is by far
the most common of all types of cancer. An estimated 3.5 million ... Melanoma Skin Cancer.
Skin cancers that are not melanoma are sometimes grouped together as non-melanoma skin
cancers because they tend to act very differently from melanomas.
Keratinocyte cancers...
... dispro‐
portions between non-melanoma skincancer and melanoma are recorded for the face. In men,
non-melanoma skin cancers on the face comprise 48% of all skin cancers, whereas melanoma
comprises ... incidence rate was recorded for both skincancer types in
men aged 55 years. Both skincancer types are more frequent in young women than in men,
however the skincancer growth rate in the population ... 2012; 53(2):135-40.
[16] American Cancer Society. Cancer Facts and Figures 2011. Available at: http://
www .cancer. org/Research/CancerFactsFigures/CancerFactsFigures /cancer- facts-fig‐
ures-2011
[17]...
... consecu-
tive colon cancer patients experienced at least a grade II
skin toxicity and were therefore enrolled in the study. The
Skindex-29 has been very well accepted by this sample of
cancer patients ...
colorectal cancer. Clinical Colorectal Cancer 2008, 7:144-8.
17. Gotlib V, Khaled S, Lapko I, Mar N, Saif MW: Skin rash secondary to
cetuximab in a patient with advanced colorectal cancer and ... patients experienced a grade 3 skin
toxicity (14 subjects), two thirds a grade 2 skin toxicity
(31 subjects).
The three health related QoL scores measured with the
Skindex-29 questionnaire in our...
...
common cancer worldwide: skin cancer. The steady increases in melanoma and non-
melanoma skincancer cases, contrast with the recent downward incidence for all other
cancers (excluding lung cancer ... IL-4, and IL-10 in the UVB irradiated skin
SKIN CANCER OVERVIEW
Edited by Yaguang Xi
Photodermatoses and SkinCancer
7
required for growth of skin tumour cells (Thompson et al., ... UV exposure: skin aging,
wrinkles, uneven skin pigmentation, loss of skin elasticity and a disturbance of skin barrier
functions are nowadays well recognized. These changes in the skin that superimpose...
...
Chapter 083. Cancer of the Skin
(Part 1)
Harrison's Internal Medicine > Chapter 83. Cancer of the Skin
Melanoma
Pigmented lesions are among the most common findings on skin
examination. ...
heavily pigmented peoples. Dark-skinned populations (such as those of India and
Puerto Rico), blacks, and East Asians have rates 10–20 times lower than lighter-
skinned whites. In keeping with ... the incidence is
inversely correlated with the latitude of residence; at any latitude, darker-skinned
persons have the lowest incidence. Melanoma is rare in children under age 10.
Table 83-1...
...
amelanotic, in which case the diagnosis is established histologically after biopsy of
a new or changing skin nodule or because of a suspicion of a basal cell carcinoma
(see below).
visibly and/or...
... the skin
above the waist; the scalp,
breasts, and buttocks are rarely
involved
Source: Modified from RJ Friedman et al: CA—
A Cancer J Clinicians
33(3):130, 1985.
Chapter 083. Cancer ...
pigment may fade off into
surrounding skin; macu
lar
portion at the edge of the nevus
Round; sharp, clear-
cut
borders between the nevus and
the surrounding skin; may be
flat or elevated
Size ...
follow-up. Examination of the lymph nodes and palpation of the abdominal
viscera are part of the staging examination for suspected melanoma. The patient
should be advised to have other family...