ca2 dynamics in the er and in
Báo cáo khoa học: Eukaryotic class 1 translation termination factor eRF1 ) the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis pptx
Ngày tải lên :
07/03/2014, 05:20
... coli in vivo can be explained by their competitive inhibition at the ribosome-binding site [32] Together, the M and C domains of human eRF1, in the absence of the N domain, are able to bind to the ... characteristic of many RNA- and DNA-binding proteins [46–48], and may facilitate easier positional rearrangement of the protein during the docking to the binding site on the ribosome or other ligands ... described in detail below The C domain of eRF1 interacts with the C domain of eRF3 [15–18], and the binding of both factors is essential for fast kinetics of the termination of translation [1] However,...
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Báo cáo khoa học: " Differential protection by wildtype vs. organelle-specific Bcl-2 suggests a combined requirement of both the ER and mitochondria in ceramide-mediated caspase-independent programmed cell death" docx
Ngày tải lên :
09/08/2014, 10:20
... specifically at the ER by binding to the autophagy-inducing protein Beclin-1 [15] Even though the role of Bcl-2 has been most intensively studied in mitochondria and the ER, Bcl-2 also localizes to the nucleus ... protein folding, lipid biosynthesis, and calcium storage in the cell - has also been implicated in the induction of both apoptosis [15] and ciPCD [2,12,13] In fact, the ER may play a key role in ... EDTA) containing 10 μg/ml pepstatin/aprotinin/leupeptin, mM sodium orthovanadate and mM NaF After removal of insoluble material by centrifugation at 10.000 × g and 4°C for 15 min, the protein concentration...
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The dynamics of literary representation and interpretation in a multilingual environment a study of selected malaysian and singaporean novels in english
Ngày tải lên :
16/09/2015, 08:30
... the point of view changes to the father of the child The switch from the narrator to other points of view is rather rapid and confusing By this inconsistency in handling the point of view, the ... Looi finds solace in the chants repeated by the nun: The two women had their hands clasped in prayer, the other end of the long white string dangling between their 32 fingers” (136) After the ... surfaces again in the communication between the grandson and the grandmother later in the narrative: ‘Let’s go and visit Ah Kheem Chae,’ said Old Mother ‘She lives in the House of Death in Sago Lane...
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The Gulf and Inland Waters The Navy in the Civil War. Volume 3. potx
Ngày tải lên :
08/03/2014, 22:20
... upon the rains and the melting of the snows in their basins The greatest average height is attained in the late winter and early spring months; another rise takes place in the early summer; the ... of the boilers and engines, where there were two and a half inches of iron, but without backing The stern, therefore, was perfectly vulnerable, as were the sides forward and abaft the engines The ... no further part in the fray Two other Confederates now approached the Cincinnati, the General Price and General Sumter One of them succeeded in ramming in the same place as the Bragg, and it...
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The Character and Influence of the Indian Trade in Wisconsin doc
Ngày tải lên :
16/03/2014, 15:20
... messenger There came a man versed in craft to my father's house with a golden chain strung here and there with amber beads Now, the maidens in the hall and my lady mother were handling the chain and ... to the woods of northern Wisconsin In the years immediately following, the Neutral Nation and the Eries fell under their power; they overawed the New England Indians and the Southern tribes, and ... in the Cumberland mountains, the other down the valley of the Kenhawa They were both the war-path of the Indians and the travelling route of the buffalo, and their first white acquaintances the...
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báo cáo hóa học:" Ill-lighting syndrome: prevalence in shift-work personnel in the anaesthesiology and intensive care department of three Italian hospitals" doc
Ngày tải lên :
20/06/2014, 00:20
... 44 14 10 42 30 82 Operating Theatre Figure personnel Percentage stress in Intensive Care and operating theatre Percentage stress in Intensive Care and operating theatre personnel none medium ... collected and analyzed the data and collaborated in writing the article EF advised in all stages of the undertaking, analyzed the data and collaborated in writing the article PDP analyzed the data and ... which were comparable to those reported by workers who were discomforted by the artificial light in the operating theatres and Intensive Care departments (Figure 6) In order to verify the hypothesis...
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model for geological risk management in the building and infrastructure processes
Ngày tải lên :
27/07/2014, 23:32
... into their systems and subsystems The methodology raises the application of the model with a cyclical and interactive character, where is prevailing the training and group decision, and the individual ... and others, who are able to obtain the executing engineers and investors in the region, area or locality where the work is located and also the correct application of the rules, regulations and ... Http://en.wikipedia.org/wiki/St._Francis_Dam The different types of geological hazards can interact with each other, and in the present predominance of one other side effect, which can complicate the situation and increase the vulnerability...
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Báo cáo y học: "Out of the sequencer and into the wiki as we face new challenges in genome informatics" doc
Ngày tải lên :
09/08/2014, 22:23
... number variants and transcript diversity Chromatin immunoprecipitation sequencing (ChIPSeq) provides an extraordinary window into the dynamics of protein-DNA binding Xin Feng (Stony Brook University, ... browser that can display sequence, read alignment, single nucleotide polymorphism and other genomic datasets stored in standard file formats Harminder Sehra (European Bioinformatics Institute, Hinxton, ... using the current sequencing platforms, in physical mapping as well as de novo assembly Frederic Choulet (Institut National de la Recherche Agronomique, Clermont-Ferrand, France) des ribed the...
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Báo cáo y học: "Surgical care for the direct and indirect victims of violence in the eastern Democratic Republic of Congo" pps
Ngày tải lên :
13/08/2014, 14:20
... support to cover all inpatient services including maternity, pediatrics, and internal medicine, as well as laboratory services and the emergency room Currently there are 32 surgical beds in the 175-bed ... (3%) were in the military 1263 (44%) procedures were performed under spinal anesthesia; 1263 (44%) under general anesthesia without intubation, and only 115 (4%) under general anesthesia with intubation ... spinal anesthesia and ketamine (general anesthesia without intubation) which are safer types of anesthesia to administer for nurse-anesthetists or anesthesia providers that are informally trained...
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Tài liệu THE NETWORKING AND INFORMATION TECHNOLOGY RESEARCH AND DEVELOPMENT PROGRAM doc
Ngày tải lên :
20/02/2014, 05:21
... practitioners and caregivers, device developers and vendors, care facility administrators, academic computer scientists and engineers, and Federal government regulators These first-of-their-kind gatherings ... incorporated into K-12, informal, and higher education o IT education and training: Develop innovative approaches to broadening interest and participation in 21st Century IT careers, including information ... need The Federal government generates and maintains the world’s largest digital collections of science and engineering data, historical records, health information, and scientific and other types...
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Bank income and profits over the business and interest rate cycle pdf
Ngày tải lên :
06/03/2014, 14:20
... and rose rather continuously (with two intermissions) up to 64 % again thereafter The share of non-interest income in total income, on the other hand, increased very steadily from below 30 percent ... to net interest margins, and Bikker and Haaf (2002) observe that the interest income, relative to total assets, shrinks following increases in other income Operating costs (overheads) are included ... account for the actual interest income less the actual interest expenses The approaches of applying either one or the other di er by the ex-post margins being determined by loan and deposit volumes,...
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Báo cáo khoa học: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism pptx
Ngày tải lên :
16/03/2014, 00:20
... implying a p53-independent mechanism of action [31] It will be interesting to determine whether other proteins that control the cell cycle are involved in the effects induced by DHEA in cervical ... cancer Oral administration of DHEA to mice inhibits spontaneous breast cancer and chemically induced tumors of the lung and colon [7]; however, its effect in cervical cancer remains unknown Therefore, ... disorders, cancer and atherosclerosis [5,6], as a result of its antiproliferative, anti -in ammatory and anti-oxidant effects [7–9] DHEA is a powerful inhibitor of carcinogenesis, in the early- and...
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the direct and indirect impact of rhetoric
Ngày tải lên :
21/03/2014, 22:53
... impact in the relationship between Celie and Sofia After Sofia's jail sentence she is very depressed, and Celie helps her the grocery shopping Showing her rhetoric of friendship and kindness ... the letters Celie's rhetoric in her relationship with Shug let her gain a new friend, contact with her beloved sister, and rediscover a joy and purpose to her life Rhetoric also ... inside Sofia and allows her to admit to Celie how she helped her and that people understand and love her Without first affecting Sofia with her rhetoric, Celie would not have experienced the assurance...
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Ovarian cancer: the recognition and initial management of ovarian cancer doc
Ngày tải lên :
22/03/2014, 16:21
... distilling and synthesising the evidence and writing recommendations • agreeing the recommendations • structuring and writing the guideline • updating the guideline The scope The remit was translated into ... review and Appendix During the analysis the following general principles were adhered to: • the GDG Chair and Clinical Lead were consulted during the construction and interpretation of the analysis ... Bulletin Cancer survival in England (Berrino 2003; Berrino et al., 2009) International comparison In this section international data are presented from EUROCARE and the International Cancer Benchmarking...
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Báo cáo khoa học: Antimicrobial and conformational studies of the active and inactive analogues of the protegrin-1 peptide docx
Ngày tải lên :
22/03/2014, 21:20
... addition, there is only one cationic Arg1 residue on the N-terminus in BM-1, rather than two arginines (Arg1 on the N-terminus and Arg18 in PG-1 or Arg17 in IB-367 on the C-terminus), one at the N- and ... as cathelicidins [11], which are synthesized as the C-terminal portion of a cathelincontaining proregion The N-terminal cathelin domain of the precursor is highly conserved at both the amino acid ... charged poles in the N- and C-terminal regions and in the turn Androctonin also has a highly hydrophilic and positively charged turn and N-terminus, but, in contrast, the C-terminus containing Pro24–Tyr25...
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báo cáo hóa học: " Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity" pdf
Ngày tải lên :
20/06/2014, 00:20
... substances in the skin, which then causes erythema to occur faster and with greater intensity following UV irradiation [33] Interesting evidence into the induction of melanoma and non-melanoma skin cancers ... provided in the study of Winn et al [137] The study of Cole et al was financially supported by WarnerLambert Company (the former maker of Listerine) It is interesting that from the same dataset, Winn ... J: Influence of alcohol in mouthwashes containing triclosan and zinc: an experimental gingivitis study J Clin Periodontol 2005, 32:539-544 156 Rotter ML: Hand washing and hand disinfection In...
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Báo cáo hóa học: "SUPPLEMENTS TO KNOWN MONOTONICITY RESULTS AND INEQUALITIES FOR THE GAMMA AND INCOMPLETE GAMMA FUNCTIONS" pptx
Ngày tải lên :
22/06/2014, 21:20
... proved the following lower and upper bounds xp + 2 1/ p − x < ex ∞ p x e−t dt ≤ a p p p x2 + −x , ap (1.6) where p > 1, x ≥ and ap = Γ + p/(p−1) p (1.7) The integral in (1.6) can be expressed in the ... The function s(z), defined in (3.5), have not any relative maximum point in the interval (0,+∞) A Laforgia and P Natalini Proof For any n ≥ consider the partial sum of series (3.5) 2n (−1)k (p ... new derivation give us the following expression 2n (−1)k (p + 1) (p + 1)s2n (z) + pzs2n (z) = k =2 k − k −1 z k! (3.10) Dividing by z and re-writing, in equivalent way, the indexes into the sum...
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Anecdotes of the Habits and Instinct of Animals, by R. Lee potx
Ngày tải lên :
28/06/2014, 19:20
... movement, that they delight in pilfering, in outwitting each other and their higher brethren—men; that they glory in tearing and destroying the works of art by which they are surrounded in a domestic ... thing, they are solemnly contemplating the intruder; they are not pelting him in play, it is their business to drive him from their domain Raise your arm, the boughs shake, the chattering begins, ... the tureen from the table, and, serving the fish, make no further comment The mistress of the family, however, when the ladies left the dining-room, slipped away from her friends, and summoning...
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Elementary Illustrations of the Differential and Integral Calculus pptx
Ngày tải lên :
28/06/2014, 19:20
... 11), and of the following: If a polygon be inscribed in a circle, the greater the number of its sides, and the smaller their lengths, the more nearly will the perimeters of the polygon and circle ... third, and fourth column are less than those in the first; nevertheless, the ratio of B to C is less in the second column than it was in the first, remains the same in the third, and is greater in the ... touching the circle at A, produce OB to meet AT in T, draw BM and BN perpendicular and parallel to OA, and join BA Bisect the arc AB in C, and draw OC meeting the chord in D and bisecting it The...
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