Ngày tải lên :
30/03/2014, 15:20
... is an important multifunctional AAA+ ATPase with two Cterminal ATPase domains after the adaptor domain, which provide the energy for major conformational changes [124] VCP forms hexamers and ... molecular basis for ARF binding and membrane association of GGAs Dev Cell 4, 321– 332 Shiba, T., Kawasaki, M., Takatsu, H., Nogi, T., Matsugaki, N., Igarashi, N., Suzuki, M., Kato, R., Nakayama, ... which is a U box homologue of yeast Ufd2 [128], and interacts with and regulates the degradation of the proteasome-associated ataxin-3, forming a trimeric complex of ataxin-3, VCP, and UFD 2a [96,127,129–131]...