antigen presentation for the generation of binding molecules
Báo cáo khoa học: A strategy for the generation of specific human antibodies by directed evolution and phage display An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom docx
Ngày tải lên :
23/03/2014, 13:20
... C noxius venom To the best of our knowledge, this is the first report of the generation of a human recombinant antibody fragment capable of neutralizing the toxic effects of the whole venom from ... of mouse weight) [13] Clone 3F was matured by three cycles of directed evolution The use of a set of stringent conditions in the third cycle allowed the selection of several improved clones The ... corresponding germ lines For clone 3F, VH3-VK3 were the closest families for VH and VL domains, respectively In the case of C1, VH3Vk1 were the families with highest scores The specificity of these two scFvs...
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Báo cáo khoa học: "Adding Syntax to Dynamic Programming for Aligning Comparable Texts for the Generation of Paraphrases" potx
Ngày tải lên :
31/03/2014, 01:20
... used to guide the alignment Starting from the bottom right entry of the matrix, we go to the matrix entry from which the value of the current cell is derived in the recursion of the dynamic programming ... Milan Theater”, the IOB value for “I” is B-NP since it marks the beginning of a nounphrase (NP) On the other hand, “Theater” has an IOB value of I-NP because it is inside a nounphrase (Milan Theater) ... V5 The results support both our hypotheses For Hypothesis I, we see that the performance of the two syntactic alignments was higher than the nonsyntactic versions In particular, Version outperforms...
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báo cáo hóa học:" A rapid method for the generation of uniform acellular bone explants: a technical note" pot
Ngày tải lên :
20/06/2014, 04:20
... participated in the cutting and staining of Page of the bone tissue RGR participated in the planning of the experiments, data analysis and the preparation of the manuscript MJS supervised the study ... the preparation of the bone cores and exposure of the samples to the different treatments, performed the microscopic analysis and helped with the planning and preparation of the manuscript PIF ... treatment for the generation of an acellular bone explant control to be used within an operating theatre is to our knowledge the repeated use of freeze-thawing cycles This method is one of the classical...
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Báo cáo hóa học: " A Generalized Algorithm for the Generation of Correlated Rayleigh Fading Envelopes in Wireless Channels" ppt
Ngày tải lên :
23/06/2014, 00:20
... addition, the algorithm should work well, regardless of the positive definiteness of the covariance matrices Furthermore, the algorithm should provide a straightforward method for the generation of complex ... on the variance of the complex Gaussian random variables at the inputs of Doppler filters as well as the characteristics of those filters The variance value of the outputs is then input into the ... powers of Rayleigh envelopes denoted as σr2j are not necessarily equal to one another Therefore, the scenario where the variances of the Rayleigh envelopes are equal to one another and the powers of...
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Báo cáo y học: " A method for the generation of standardized qualitative dynamical systems of regulatory networks" doc
Ngày tải lên :
13/08/2014, 23:20
... [4,5] There are cases, however, where the underlying biochemical reactions are not known for large parts of a pathway, but the direction of the flow of information is known, which is the case for ... (see for example [6,7]) In these cases, the directionality of signaling is sufficient for developing mathematical models of how the patterns of activation and inhibition determine the state of ... they have all been carried out to describe the molecular components of the process, but not to study the dynamical behavior of the network As a result, most of the schematic representations of...
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PERIPHERAL BLOOD a SIMPLE CELL SOURCE FOR THE GENERATION OF ANGIOGENIC PROGENITORS FROM MONOCYTES
Ngày tải lên :
09/09/2015, 10:13
... to the dimerisation of two receptors depending on which are the binding chains Therefore PDGFR-αα binds all three isoforms of PDGF, PDGFR-αβ can bind PDGF AB and BB and PDGFR-ββ is specific for ... co-localisation of cells with the endothelial network is a pericyte specific behaviour Further we analysed the ability of cells to stabilise the formed endothelial network Figure 1-5: Tubular network formation ... reduced in wounds of treated animals and the overall number of pericytes decreased (Rajkumar et al 2006) Therefore pericytes seem not to be necessary for the initial formation of blood vessels...
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2D optical trapping potential for the confinement of heteronuclear molecules 5
Ngày tải lên :
30/09/2015, 10:12
... another PBS The first PBS cleans up the polarization of the beam, transmitting only the horizontally polarized component of the beam The HWP allows a rotation of the beam polarization before the ... of the beam at the power meter as we fine tune the reflection angle of the beam with the mirror mount Figure 5.19: The 2f-2f configuration used in the measurement of the angle-dependence of the ... Experimental setup for the beam profile measurement The red arrow indicates the path of the main beam, measured by the Beam Master 5.2 Beam Profile Measurement Before the SLM Once we establish the laser...
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2D optical trapping potential for the confinement of heteronuclear molecules 7
Ngày tải lên :
30/09/2015, 10:13
... this choice of initial phase, we recover the flat-top profile at the Fourier Plane exactly if the amplitude profile of the input beam matches the amplitude profile of the inverse FT of the flat-top ... 2008] The first step of this algorithm is to produce the initial guess for the SLM phase modulation This quantity is set to be the argument of the phase part of the inverse Fourier Transform of the ... limited to the phase of the beam Therefore, the modulated field at the input plane EIP has a restricted shape where the amplitude is given by the initial gaussian distribution of the laser and the phase...
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2D optical trapping potential for the confinement of heteronuclear molecules 6
Ngày tải lên :
30/09/2015, 10:13
... SLM By observing the reflection off only the central pixel of the SLM, we map the position of the center of the SLM in terms of the pixel of the camera Secondly, we want to map the distance between ... Evolution of the output profile RMS and maximum error in function of the number of iterations with the second algorithm The evolution of the RMS and maximum error of the beam during the iterations ... (less than 50 Hz) component of the signal for the reflection off the flat-top pattern and the local region of the laser output The noise found in the reflection off the flat-top pattern can be...
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2D optical trapping potential for the confinement of heteronuclear molecules 4
Ngày tải lên :
30/09/2015, 10:13
... propagation of the input field EIP from the SLM to the output plane Neglecting the finite aperture of the lens, the field at the Fourier plane is given by the Fourier Transform of the input field ... Figure 4.9: The pixel structure of the DLP3000 [Texas Instruments, ] Figure 4.10: The representation of the DLP3000 pixel geometry for the simulation The pink area represents the pixels of the DLP3000 ... power of the input Gaussian profile By numerically integrating the Super-Lorentz (SL) function, the power of the flat-top profile and therefore the beam shaping efficiency is calculated for any...
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2D optical trapping potential for the confinement of heteronuclear molecules 3
Ngày tải lên :
30/09/2015, 10:13
... multiplying the field with the lens quadratic phase factor, and then propagating it over another f distance Let us perform the explicit calculation sequentially The field at the plane just before the ... xd¯ y (A.3.3) Therefore, aside from a constant phase shift term e2ikf , the output field is a Fourier Transform of the input field, hence the name of Fourier imaging in this case For the relay telescope, ... the quadratic phase factor e 2f of the lens exactly cancels out the quadratic phase term in the field Ebl Hence the expression of the field at the plane just after the lens Eal is given by: Eal...
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2D optical trapping potential for the confinement of heteronuclear molecules 2
Ngày tải lên :
30/09/2015, 10:13
... The typical waist size of the beam used in an optical trap is of the order of 100 µm Compared to the wavelength which is of the order of µm, the width of the cloud in a single beam setup is therefore ... consideration for designing the optical trap is to optimize the lifetime of the molecules in trap We had first discussed the need of confining the molecules in a 2-dimensional geometry instead of a 3-dimensional ... Firstly, we can compare the width of the Gaussian distribution of the molecular cloud which is described by the length lc Taking the ratio of lc for the single beam and the optical lattice, we...
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2D optical trapping potential for the confinement of heteronuclear molecules 1
Ngày tải lên :
30/09/2015, 10:13
... ease of modifying the potential landscape In fact, the optical potential is formed by the interaction between a laser and the cold gas, and the potential can be tuned by adjusting the shape of the ... creation of a uniform potential is a lot more involved To form a uniform potential, the intensity of the laser needs to be converted into a flat-top pattern consisting of a uniform distribution at the ... and the optical trap [Ashkin et al., 1986] The optical trap is normally used at the later stage of the experiment due to its ability to trap the atoms regardless of their magnetic state and the...
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Some strategies to give an effective PowerPoint presentation for the 4th year student of English Faculty, Hanoi Open University
Ngày tải lên :
18/04/2013, 08:57
... Scope of the study - Method of the study - Design of the study Development includes chapters: Chapter 1: Literature review - Definition of presentation - Types of presentation - The role of presentation ... point presentation is a presentation which is carried out with the support of PowerPoint, a presentation software program 1.2 The structure of a PowerPoint presentation Like other kinds of presentation, ... Use 1-2 slides per minute of your presentation - Make your 1st or 2nd slide an outline of your presentation, then follow the order of your outline for the rest of the presentation Remember to...
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Business development strategies of Phu My thermal power production division belonging to powe generation corporation 3 for the period of 2013 - 2018
Ngày tải lên :
26/03/2015, 10:56
... supports for the implementation of mode and policy of the State; EVN also implemented the mission of providing the electricity for the national economy and securing the national power well However, the ... evaluation is the focus on identifying and assessing the tendencies and the events beyond the control of the company For the managers who can offer the strategy aiming to take use of the opportunities ... a part of consequence of the longterm impact of other macro factors The impact of the cultural and social factors is longer and more elegant than other ones On the other hand, its scope of impact...
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The generation of native human monoclonal antibodies with neutralising activity for dengue virus 2
Ngày tải lên :
11/09/2015, 09:56
... Western blot of 14C10 mAb binds to E protein of DV1 Figure 7.10 Western blot and native gel of 14C10 mAb against DIII of E protein of DV 138 139 xiii Figure 7.11 Graph of binding affinities of 14C10 ... 7.7.2 Comparison of neutralizing efficiency of 14C10 mAb within Genotypes 150 7.8 Mechanism of 14C10 mAb 153 7.9 ADE profiles of 14C10 mAb 155 7.9.1 Development of ADE among the DV serotype 155 ... prevalence of DF and DHF as shown by WHO Figure 1.2 Ribbon drawing of E protein Figure 1.3 Schematic representation of the polyprotein processing for flaviviruses Figure 1.4 Proposed rearrangement of...
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The generation of native human monoclonal antibodies with neutralising activity for dengue virus 3
Ngày tải lên :
11/09/2015, 09:56
... triggers dissociation of the prM/E heterodimers, which leads to the formation of 90 dimers that lie flat on the surface of the particle, with prM capping the fusion peptide of the E protein This ... structure of the mature particle (Zhang, Corver et al 2003) The immature particles formed in the ER mature as they travel through the secretory pathway The slightly acidic pH (~5.8 - 6.0) of the trans ... the infection Based on the shape of the monomer and the location of the antibody epitopes, Rey et al postulated that the E protein has a „flat‟ topology along the surface of the virus lipid bilayer...
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