... to share this knowledge and use it in their schooling.
30
In most parts ofthe world, education is forthe most part the preserve ofthe few (elites). The
choice of which language or dialect ... enable them to take active roles in their communities.
Adult education is crucial and better placed to fight poverty than formal education because it
is involved in theeducationofthe most ... to information andeducationofthe
groups involved.
Adult education does not only deal with issues ofeducation involving adults, but it also
directly and indirectly influences the education...
... hydrogen bonds
between K12 andthe side chains of N10
and Q64, which maintain the unusual Rama-
chandran angles forthe K12 residue, and a
Ramachandran scatter plot forthe K12 resi-
dues in 21 ... features ofthe Y74W* mutant of
PfTIM need to be rationalized: (a) the reduced stability
of the dimeric structure, and (b) the significantly lower
value of k
cat
, suggesting an impairment ofthe catalytic
efficiency ... nature. The growing body
of sequence and structural data on these well-studied
enzymes affords an opportunity to evaluate the conse-
quences of mutations. In the case of TIM, only nine of
the 220–250...
... 129140 ê 2004 FEBS
Theroleof helix 8 andofthe cytosolic C-termini in
the internalization and signal transduction of B
1
and B
2
bradykinin receptors
Alexander Faussner
1
, Alexandra Bauer
1
, ... be
accounted for by the amount of internalized agonist
[20]. As the internalization is expressed in percentage
of total binding, decreasing the binding affinity of the
Roleof helix 8 and C-termini ... site
because the presence of detergent or membrane lipids
influences the formation of a helical structure. These
authors proposed that activation ofthe receptor, and
subsequently ofthe G protein,...
... determine the
pH optima, the ionization constants (pK
a
)ofthecatalytic
glutamates (E187 and E399) in the ES complex and in the
free enzyme (E) of Sfbgly50 mutants were determined. The
pK
ES
and pK
E
are ... R97
and E399 is probably a major cause ofthe shift in the pK
a
of E399. Therefore, R97 facilitates the ionization of the
catalytic nucleophile by stabilizing its charged state.
Fig. 5. Effect of ... result, the pH optimum ofthe Y331F mutant
(7.0) is higher than that ofthe wild-type Sfbgly50 (6.2)
(Fig. 5). The effect of this mutation on the E399 ionization
is the same as observed forthe mutation...
... specifications include mother’s and father’s age at the time ofthe child’s birth in quadratic, indicators of whether the mother or father is currently a smoker,
indicator of whether the mother smoked during ... specifications include mother’s and father’s age
at the time ofthe child’s birth in quadratic, indicators of whether the mother or father is currently a smoker, indicator of whether the mother smoked during ... levels of higher education. The LFS data, on the other hand, include a
continuous educational measure. Table A1 in the Appendix compares the age at which mothers and
fathers left full-time education...
... urea-induced and GdnHCl-induced
changes in the secondary structure ofthe proteins, we
analyzed the UV CD spectra of MS2 and VLPs in the
absence and presence of 5.0 m and 9.0 m urea and
3.5 m and 5.0 ... chang-
es were analyzed by variation of spectral center of mass of trypto-
phan emission in the absence of bis-ANS for (m) dlFG, (r ) sc-dlFG.
and in the presence of bis-ANS for (e) sc-dlFG andthe return ... stability of genetic fusion ofthe two sub-
units ofthe dlFG dimer using the variant named
2CTdlFG, which takes advantage ofthe physical prox-
imity ofthe N-terminus and C-termius ofthe two
monomers...
... primary factors of production, and the
general exclusion or trivialization oftheroleof knowledge, was not limited
only to the sphere of macroeconomics. The most compelling theories of
international ... inclusion of various aspects of
knowledge. Early extensions included human capital and skilled labor, and
technology. The neo-technology theories focused on theroleof R&D and the
creation of new ... of industrial clustering.
The organizations ofthe first economy, either because of their charter to do
research as in the case of universities and R&D laboratories, or as a by-
product of...
... the
roleof feedback under motor uncertainty, such as is
more typical in real-world situations. We added random
delays to the hand motion before the onset of move-
ment and before the onset of ... briefly before the start ofthe first trial,
with full feedback sensibility, so that they could get used
to the control mechanism ofthe hand.
Subjects performed the four blocks ofthe experiment
over ... given trial i we
therefore define the grasp force, f
i
, as the average grip
force (in Newtons) applied to the object forthe duration
of its elevation.
Ramp Duration
The duration ofthe c ontrol...
... this article as: Hughes-Fulford and Li: Theroleof FGF-2 and BMP-2
in regulation of gene induction, cell proliferation and mineralization.
Journal of Orthopaedic Surgery and Research 2011 6:8.
Submit ... administration of adenoviral
BMP-2 vector improves the formation of bone in osseous defects. Gene
Ther 2007, 14:1039-1044.
Hughes-Fulford and Li Journal of Orthopaedic Surgery and Research 2011, ... 6:8
http://www.josr-online.com/content/6/1/8
Page 7 of 8
RESEARCH ARTICLE Open Access
The roleof FGF-2 and BMP-2 in regulation of
gene induction, cell proliferation and
mineralization
Millie Hughes-Fulford
1,2,3,4*
, Chai-Fei...
... effi-
ciency of bone growth factors FGF-2, TGFb, and PGE2
markedly enhanced the synthesis ofthe total protein con-
tent ofthe dishes (Table 1)
Rate of proliferation was dependent on the specific
GF. ... article as: Hughes-Fulford and Li: Theroleof FGF-2 and BMP-2
in regulation of gene induction, cell proliferation and mineralization.
Journal of Orthopaedic Surgery and Research 2011 6:8.
Submit ... major role in wound healing [6,7].
To evaluate the physiological activity of FGF-2 and
other growth factors, we studied their relative ability to
influence proliferation of osteoblasts at a site of...
... equality, the rule
of law and respect forand protection of human rights […] Recognizing the need to strengthen the important roleof
the United Nations in the prevention of violent conflicts, and ...
for addressing poverty and vulnerability in all contexts.
They have emerged from the growing realization of
the need to put the poor and all aspects of their lives
and means of living at the ... and […] condemns
categorically the illegal exploitation ofthe natural resources and other sources of wealth ofthe Democratic Republic
of the Congo, urges all States, especially those in the...