advances in the synthesis and applications of organobromine compounds

Báo cáo y học: " Advances in the genetics and epigenetics of gene regulation and human disease" pps

Ngày tải lên : 14/08/2014, 17:22

... and the position of cross-overs Using in silico and in vitro analyses, Sapienza’s group have shown a relationship between increased rates of meiotic recombination and genomic imprinting Imprinted ... method for determining transcription factor binding sites, Hallikas reported the binding sites of the transcription factors GLIs, TCF4 and c-ETS1, which are involved in different signaling pathways ... involved in cell-cycle control and cell-size regulation in Drosophila Using flow cytometry, Björklund and colleagues analyzed the RNAi-induced loss -of- function of 70% of the genes in Drosophila, including...

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enterprise network testing [electronic resource] the role and applications of testing in pre-peployment, migration, and post-deployment, network operations

Ngày tải lên : 30/05/2014, 23:50

... managed infrastructures to handle them On the contrary, companies are demanding that their existing converged networks be capable of handling the demands of TelePresence and other next-generation applications ... help in educating the network engineers involved in the testing about the feature or network they are going to be deploying and soon supporting Second, it will help you document the part of the ... Explaining the different types of testing that complement decision making during the various phases of a network’s lifecycle ■ Outlining a business and technical blueprint for developing a testing...

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Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests

Ngày tải lên : 28/10/2013, 11:15

... Conclusions, including the results of the November 2001 Workshop Management Framework - Introd uced Marine Pests Management capabilities and approaches  APEC and the MRCWG have a role in liaising with ... Within APEC little is known on the introduction of marine pests  Little practical information on measures to prevent introductions  Lack of knowledge in what individual countries are doing ... NACA to enhance the effectiveness of existing instruments within APEC  Institutional arrangements for managing the marine environment is fragmented in most economies  Baseline surveys to identify...

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Tài liệu NEW ADVANCES IN THE BASIC AND CLINICAL GASTROENTEROLOGY docx

Ngày tải lên : 12/02/2014, 16:20

... demonstrated their capacity to stimulate the production of intestinal mucines, their trophic effect on intestinal epithelium, the reestablishment of the intestinal mucosa integrity, the stimulation of the ... probiotics can alter the intestinal microflora and reduce the growth of pathogenic microorganisms in the intestines of preterm infants, decreasing the incidence of necrotizing enterocolitis and sepsis ... Probiotics and infections The most valid indication of the probiotic remains the decrease of intestinal infections In fact, the literature shows that the probiotic can reduce the severity and number of...

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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx

Ngày tải lên : 15/02/2014, 13:20

... useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered Vol 45 / No RR-4 MMWR and the vaccinee’s age at the time of vaccination ... resurgence in the incidence of TB occurred in the United States and included increases in the number of TB cases among adults and children and outbreaks of multidrug-resistant TB (MDR-TB) involving ... Control and Prevention The role of BCG vaccine in the prevention and control of tuberculosis in the United States: a joint statement by the Advisory Council for the Elimination of Tuberculosis and the...

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Tài liệu Trends in the Fees and expenses of Mutual Funds, 2010 pptx

Ngày tải lên : 19/02/2014, 15:20

... basis points of the 11 basis-point decline in the average expense ratio of funds of funds over the period (labeled in Figure 13 as “Fall in expense ratios of individual funds”) By definition, the ... inflation by taking the fee breakpoints available in 2010 and multiplying by the Consumer Price Index in December 2000 and dividing by the Consumer Price Index in December 2010 The front-end ... endowments, and other institutional investors investing for their own accounts, rather than on behalf of retail investors Stock Funds The average fees and expenses paid by stock fund investors declined...

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Tài liệu Trends in the Expenses and Fees of Mutual Funds, 2011 ppt

Ngày tải lên : 19/02/2014, 15:20

... declined in 2011 owing to declines in the expense ratios of individual funds, an increase in the demand for index funds, and a continuing shift by investors in both actively managed and index ... percentage of the assets that the financial professional manages for an investor, rather than as a percent of the dollars initially invested Over time, brokers and other financial professionals ... collects the 12b-1 fee, passing the bulk of it to the financial professionals serving fund investors Alternatively, investors may pay the professional an asset-based fee directly In such cases, the...

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Tài liệu Rubber plantation performance in the Northeast and East of Thailand in relation to environmental conditions docx

Ngày tải lên : 21/02/2014, 04:20

... On the other hand, in the far Northeast, along the Mekong River, over 2030 mm is received annually Variation in the average amount of rainfall is therefore notable in the Northeast During the ... in Thailand, and the University of Helsinki This study was also a joint undertaking in the long series of academic collaboration between the universities of Kasetsart and Helsinki 1.2 Scope and ... Research Institute of Thailand (RRIT) and the Office of the Rubber Replanting Aid Fund (ORRAF) The RRIT works under the Department of Agriculture (Ministry of Agriculture and Cooperatives), and its...

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Tài liệu recent trends in the law and policy of bioenergy production promotion and use docx

Ngày tải lên : 21/02/2014, 05:20

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Tài liệu ‘Unheard voices’: listening to Refugees and Asylum seekers in the planning and delivery of mental health service provision in London. pptx

Ngày tải lên : 24/02/2014, 18:20

... ONE is the INTRODUCTION This includes an outline of the CONTEXT and main themes, the motivation and purpose of the study - the why and how PART TWO is THE REASEARCH - METHODOLOGY and FINDINGS PART ... component in the integration process: The first step towards the integration of refugees must be to identify and help with their most pressing needs Finding and settling them into safe and appropriate ... GUIDE is the last section This provides a discussion of the main themes as they emerged in the service user interviews (as listed above in the ‘Findings’ section) It breaks the themes down into manageable...

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Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf

Ngày tải lên : 06/03/2014, 09:22

... (disordered in the ligand-free state in YbgJ) In the absence of the ligand, the lid part is separated from the active site, which leads to a more open active site Upon the binding of ligand in the acyl-enzyme ... conformations of the regions at 100-105 and 303-309 aa in the N form, and we investigated the following points First, these areas are not involved in any contacts with other molecules in crystals in all the ... basis of their crystal structures and the conserved amino acid residues (aa) of their active sites, these glutaminases are classiﬁed into a large group of bacterial penicillin-binding proteins and...

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Gentle Measures in the Management and Training of the Young docx

Ngày tải lên : 06/03/2014, 20:20

... upon the piazza with blocks and other playthings, and finally had gone into the house, leaving all the things on the floor of the piazza, instead of putting them away in their places, as they ... had been enjoined upon them as, for example, when they left the door open in coming in or going out, in the winter; or interrupted their mother when she was reading, instead of standing quietly ... in accomplishing the result, and in a manner altogether more agreeable to both parties The third will make the work of forming the habit of obedience on the part of the mother, and of acquiring...

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Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt

Ngày tải lên : 07/03/2014, 00:20

... shown in Fig 1B, the distance between the two termini of the inserted Ca2+-binding sites in the model structure of the EF-hand of STIM1 is within ˚ 15 A Accordingly, a total of six glycine linkers ... Ca2+-coordinating loop positions and was introduced to perturb the Ca2+-binding ability of the grafted EF-hand of STIM1 (B) Modelled structure of the engineered protein with the grafted EF-hand Ca2+-binding ... EF-hand motif in STIM1 is occupied by Ca2+ Removing the proposed Ca2+-coordinating residues in positions and of the EF-hand motif signiﬁcantly compromised the metal-binding capability of the engineered...

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New Advances in the Basic and Clinical Gastroenterology Edited by Tomasz Brzozowski potx

Ngày tải lên : 07/03/2014, 20:20

... improve the health of the host The mode of action of probiotics involves a mutual interaction with intestinal cells and other microflora present in the gut In these two chapters, the influence of ... characteristics of the esophagus including the extrinsic and intrinsic innervations Moreover, they had concentrated on the reflex part of swallowing involving both the afferent and efferent pathways The ... demonstrated their capacity to stimulate the production of intestinal mucines, their trophic effect on intestinal epithelium, the reestablishment of the intestinal mucosa integrity, the stimulation of the...

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Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx

Ngày tải lên : 15/03/2014, 23:20

... timescale in both of the free modules Thus, these loops are strong candidates for binding sites of other complement and ⁄ or regulatory proteins The large insertion between E and F strands in C1r ... strands B and C, known as the ‘hypervariable loop‘, D and E, E and F, F and G, and G and H are particularly tolerant of longer insertions [19] In multimodular proteins, however, insertions in the ... of a tyrosine in strand C of CCP4 in place of an asparagine in C1r CCP2 (N379), and based on the results of the present perturbation study, we suggest that the inter-CCP ﬂexibility in C1r is...

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Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt

Ngày tải lên : 20/03/2014, 03:20

... ung th in vitro, thấy quercetin làm thoái giáng đột biến p53 - protein, làm ngừng chu kỳ tế bào giai đoạn G1 , ức chế tyrosin - kinase, ngăn chặn hoạt tính protein - ras In vitro, quercetin ức ... Curcumin có nhiều ảnh hởng đến sinh lý bệnh học tế bào ung th: in vitro, curcumin làm ngừng chu kỳ tế bào u, thúc đẩy chết theo chơng trình (apoptosis) Tuy nghiên cứu hạn chế, nhng thấy curcumin ... bào khác nhau, thấy quercetin làm tăng hiệu lực điều trị cisplatin, adriamycin, busulfan, cyclophosphamid làm tế bào ung th giảm đề kháng với gemcitabin topotecan Bromelain Là hỗn hợp protease chứa...

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Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc

Ngày tải lên : 23/03/2014, 09:20

... group in the a position of the fatty acyl residues The signals that correspond to the resonance of the methine proton of the a carbon (d) and that of the carbon bearing the methyl group near the ... unknown, and the speciﬁc roles of the various members of the DIM family, e.g DIM A and DIM B, in these functions have never been investigated The recent developments in our understanding of the biosynthetic ... obtained for four mice, indicating that fewer than 50 bacteria of the PMM56 mutant strain were present in the spleen of these mice For the determination of the number of PMM56 bacteria present in...

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Báo cáo khoa học: A steady-state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor-1 in the absence and presence of vitronectin ppt

Ngày tải lên : 23/03/2014, 17:21

... binding of TM by thrombin Binding of the carboxy-terminal part of the reactive center loop of PAI-1 in the small cleft formed by the 60-loop and VR1 loop can be envisioned The kinetics of the interaction ... PAI-1/VN complexes, suggests the involvement of the chondroitin sulphate of rl-TM in the binding of PAI-1/VN Indeed, both in the absence and presence of PAI-1, the interaction of rl-TM with immobilized ... Pro37 and Gln38 are involved in the binding of TM to thrombin [27,31] These residues therefore comprise the most likely overlapping binding site for TM and PAI-1 on thrombin, as they are also of...

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UPDATES IN THE DIAGNOSIS AND TREATMENT OF VASCULITIS pot

Ngày tải lên : 30/03/2014, 00:20

... and prolonged survival of patients with AASV, it has its drawbacks; the worst being life-threat‐ ening infections early in the course of the disease and risk of malignancy in late stages of the ... extravasation and perivascular deposition of immune complexes The increased tissue staining during the resolution phase, on the other hand, suggests a possible function of VEGF in the resolution of vascular ... [52] IL-17 induces secretion of neutro‐ phil-attracting chemokines, and release of pro-inflammatory cytokines (IL-1β, TNF-α) capa‐ ble of increasing expression of PR3 on the surface of neutrophils...

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Updates in the Diagnosis and Treatment of Vasculitis Edited by Lazaros I. Sakkas and Christina Katsiari pptx

Ngày tải lên : 30/03/2014, 18:20

... use of the work must explicitly identify the original source Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the ... and prolonged survival of patients with AASV, it has its drawbacks; the worst being life-threat‐ ening infections early in the course of the disease and risk of malignancy in late stages of the ... extravasation and perivascular deposition of immune complexes The increased tissue staining during the resolution phase, on the other hand, suggests a possible function of VEGF in the resolution of vascular...

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