a brief introduction to the current status

pyrethroids from chrysanthemum to modern industrial insecticide

Ngày tải lên : 29/05/2014, 23:59

... originally a wild plant, is native to the Dalmatian region of the former Yugoslavia and Persia It is classiﬁed taxonomically into the following three species [2]: Chrysanthemum cinerariaefolium (Tanacetum ... Japan n.matsuo@kincho.co.jp Health & Crop Sciences Research Laboratory Sumitomo Chemical Co., Ltd 4-2-1 Takatsukasa Takarazuka Hyogo 665-8555 Japan morit7@sc.sumitomo-chem.co.jp Editorial Board ... useful to the reader The coverage is not exhaustive in data, but rather conceptual, concentrating on the methodological thinking that will allow the nonspecialist reader to understand the information...

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Báo cáo khoa học: Regulation of secretases by all-trans-retinoic acid pot

Ngày tải lên : 16/03/2014, 01:20

... 5¢-CCAGC GTCCACCAACTTATTAC-3¢; murine ADAM9 forward, 5¢-CTTAACATCCCGAAGCCTGAC-3¢; murine ADAM9 reverse, 5¢-CTCACTGGTCTTCCCTCTGC-3¢; human ADAM10 forward, 5¢-TTCAGGAAGCTCTGGAGGA A- 3¢; human ADAM10 ... 5¢-AGCACTGTGTTGGCGTACAG-3¢; murine b-actin forward, 5¢-AGCCATGTACGTAGCCATCC-3¢; murine b-actin reverse, 5¢-CTCTCAGCTGTGGTGGTG AA-3¢; human ADAM9 forward, 5¢-GAATGAATCACG ATGATGGGAG-3¢; human ADAM9 reverse, ... cellular membrane, whereas ADAM17 translocation to the cytoplasm was seen after h of treatment, and continually increased over the 24 h of testing ADAM17 ADAM9 µM ATRA (h) ADAM10 looking particularly...

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Báo cáo khoa học: All-trans-retinoic acid inhibits collapsin response mediator protein-2 transcriptional activity during SH-SY5Y neuroblastoma cell differentiation pptx

Ngày tải lên : 16/03/2014, 12:20

... regulates polarized Numb-mediated endocytosis for axon growth Nat Cell Biol 5, 819–826 10 Arimura N, Menager C, Kawano Y, Yoshimura T, Kawabata S, Hattori A, Fukata Y, Amano M, Goshima Y, Inagaki ... regulated at the transcriptional level gives us another example of a coordinated cell response at both the mRNA synthesis and protein activation stages Experimental procedures Materials ATRA and ActD ... boric acid and mm EDTA, pH 8.3) After the electrophoresis, the gel was dried, autoradiographed, and analyzed using imagemaster software (Amersham Biosciences) RT-PCR analysis Total RNA (2 lg) was...

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Báo cáo khoa học: Interaction of gymnemic acid with cyclodextrins analyzed by isothermal titration calorimetry, NMR and dynamic light scattering doc

Ngày tải lên : 16/03/2014, 14:20

... for the dilution heat (A) , and plotted against the molar ratio (GA ⁄ c-CD) The data were ﬁtted using a nonlinear least-squares method Table Thermodynamic parameters of the interaction between GA ... glucuronic acid and c-CD (data not shown), the aglycone portion of GA should penetrate into the hydrophobic pocket of c-CD To determine the thermodynamic parameters, the area of each exothermic peak as ... least-squares method (Fig 2E) The thermodynamic parameters at 25 °C are summarized in Table Similar thermodynamic parameters at different pH values between 4.5 and 9.5 indicate that the chemical structures...

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Báo cáo khoa học: A novel mannitol teichoic acid with side phosphate groups ofBrevibacterium sp.VKM Ac-2118 ppt

Ngày tải lên : 23/03/2014, 15:21

... Smirnov, A. V., Kulakovskaya, T.V & Kulaev, I.S (2002) Exopolyphosphatase of the halotolerant bacterium Brevibacterium sp.strain VKM Ac-2118 grown at normal and enhanced salinity Doklady Acad Nauk ... corresponding carbon atom resonates at d 71.1) In turn, there was a correlation between the latter proton and the proton of a –CHOP– group at d 4.37 (the corresponding carbon atom resonates at d 75.3) ... teichoic acid Acid degradation of the trichloroacetic acid extract (crude preparation) yielded mannitol phosphates and glycerol phosphates Therefore, it was necessary to establish whether these...

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Báo cáo Y học: Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid pdf

Ngày tải lên : 31/03/2014, 15:20

... and Rac2 isoforms in the membrane The plasma membrane fraction was separated from neutrophils and HL-60 cells were harvested at 0, 1, 3, and days after ATRA treatment Rac-PAK binding assay was ... clear in the plasma membrane fraction from either the undifferentiated cells or mature neutrophils (Fig 4B) These data suggest that Rac and PAK located in the membrane may interact to play a role ... ATRA for a week, and Rac and PAK were assayed in both cytosol and membrane fractions Rac occurs as two isoforms (Rac1 and Rac2) that are 92% identical in amino-acid sequence and Rac2 is more abundantly...

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Báo cáo sinh học: "Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells" ppt

Ngày tải lên : 18/06/2014, 19:20

... mitochondrial depolarization, which resulted in caspase-3 associated apoptotic cell death Thus, Aurora kinase inhibitor VX-680 offered as a novel therapeutic agent in treatment of ATRA-resistant ... an interaction of a number of key cellular regulatory pathways, including cell proliferation pathway, cell survival pathway, caspase activation pathway, tumor suppressor pathway, death receptor ... pathway, mitochondrial pathway and protein kinase pathway Most cells apoptosis pathway is through mitochondrial-mediated pathway, which is mostly regulated by Bcl-2 family, including the antiapoptotic...

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báo cáo hóa học: " All-trans retinoic acid induces COX-2 and prostaglandin E2 synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2" potx

Ngày tải lên : 19/06/2014, 22:20

... in the lumbar spinal cord [19] When ATRA was administered intrathecally, the sensitization-like effect was inhibited by a RARpan-antagonist and associated with a modulation of COX-2 and IL-1 activities ... [21] Materials and methods Drugs and other reagents The RARs pan-antagonist ATRA (all trans-retinoic acid) was purchased from Sigma (St Louis, MO) The selective RAR pan-antagonist (LE540) and RXR ... using a commercially available enzyme immunoabsorbent assay (EIA) kit (Cayman Chemical Company, Ann Arbor, MI) following the manufacturer's protocol The assay was performed in a total volume of...

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báo cáo hóa học:" Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells" ppt

Ngày tải lên : 20/06/2014, 03:20

... mitochondrial depolarization, which resulted in caspase-3 associated apoptotic cell death Thus, Aurora kinase inhibitor VX-680 offered as a novel therapeutic agent in treatment of ATRA-resistant ... an interaction of a number of key cellular regulatory pathways, including cell proliferation pathway, cell survival pathway, caspase activation pathway, tumor suppressor pathway, death receptor ... pathway, mitochondrial pathway and protein kinase pathway Most cells apoptosis pathway is through mitochondrial-mediated pathway, which is mostly regulated by Bcl-2 family, including the antiapoptotic...

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Báo cáo khoa học: "Effects of Combination Dietary Conjugated Linoleic Acid with Vitamin A (Retinol) and Selenium on the Response of the Immunoglobulin Productivity in Mice" pdf

Ngày tải lên : 07/08/2014, 17:22

... secretory IgA concentration was done by the sandwich ELISA [8,32] S tatis tica l an a ly sis Data were analysed by one-way analysis of variance followed by Duncan's multiple-range test to identify ... CLA2 and CVA2 had a significant decrease compared to control CS2 was slightly increased compared to other 1.5% CLA groups, but there was no significant difference among them CVA1, CVA2, CS1 and ... hours, the samples were allocated into 50㎕ at -80℃ until IgA analysis P re p ara tion o f th e gu t lu m e n la va ge After blood collection, the end of the duodenum and the cranial part of the...

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Báo cáo y học: "All-trans retinoic acid suppresses interleukin-6 expression in interleukin-1-stimulated synovial fibroblasts by inhibition of ERK1/2 pathway independently of RAR activation" ppsx

Ngày tải lên : 09/08/2014, 01:22

... pairs [bp], 59°C), RARα (sense: 5'-ACCAGATTACCCTTCTCAAGG-3', anti-sense: 5'-GGTACCGCGTGCAGATT-3', NM 031528, 65 bp, 58°C), RAR-β (5'-TCTTAATGAAAATCACAGATCTCCGC-3', antisense: 5'-CCAGGAATTTCCATTTTCAAGG-3', ... Nakajima T, Kinoshita S, Sasagawa T, Sasaki K, Naruto M, Kishimoto T, Akira S: Phosphorylation at threonine-235 by a rasdependent mitogen-activated protein kinase cascade is essential for transcription ... 5'-CTGCACCGGGCAGGGTGGAAT-3', anti-sense: 5'-CTGGACGGAAACCGAGCGGTG-3', NM 031765, 65 bp, 66°C), and RP29 (sense: AAGATGGGTCACCAGCAGCTCTACTG-3', antisense: 5'-AGACGCGGCAAGAGCGAGAA-3', NM 012876, 70 bp, 59°C) The quantity...

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Báo cáo khoa học: "Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines" docx

Ngày tải lên : 09/08/2014, 09:21

... symbols) The data are mean values (and standard deviations) from three independent determinations for each treatment modality The survival data after combined treatment are normalized to SAHA toxicity ... that cell cycle regulation changes and a p53-independent apoptotic pathway are the major mechanisms for the sensitization to HIT by SAHA We further assessed apoptosis 24 and 48h after HIT 12 Apoptosis ... the data and draft the manuscript, AEK aided in study design and provided the necessary laboratory equipment, VE performed experimental procedures (FACS analysis) and helped to analyze the data,...

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báo cáo khoa học: " All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein" pdf

Ngày tải lên : 10/08/2014, 10:20

... TW and YS have carried out the study design, statistical analyses and drafted the manuscript All authors read and approved the final manuscript Competing interests The authors declare that they ... 24 Taguchi T, Sonobe H, Toyonaga S, Yamasaki I, Shuin T, Takano A, Araki K, Akimaru K, Yuri K: Conventional and molecular cytogenetic characterization of a new human cell line, GIST-T1, established ... completely the migration of these cells (data not shown) All together, the data suggested that ATRA may be useful to prevent the invasion or metastasis of GIST cells Cytotoxic effect of combination...

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Multi dimensional coordination polymers and rings containing trans, trans muconate anions with auxiliary ligands

Ngày tải lên : 11/09/2015, 10:06

... gratitude to Dr Sudip, Dr Rakesh, Dr Meng Tack, Dr Tian Lu, Dr Wei Lee, Dr Mangayarkarasi, Abdul, Saravanan, Goutam, Jeremiah, Raghavendar and Anjana for their invaluable support, suggestions and ... organic ligands extending in an array The design and synthesis of metal-organic coordination polymers has attracted special interest due to their potential applications in gas storage/separation, ... 19 a) A view showing the connectivity of the nodal unit giving a two-dimensional (4,4) square grid b) A graphical diagram representing a (4,4) square grid in the ab-plane a) A graphical diagram...

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FATTY ACID COMPOSITION INCLUDING TRANS FATTY ACIDS CONTENT OF SELECTED VIETNAMESE INSTANT NOODLES

Ngày tải lên : 28/08/2013, 16:28

... saturated fatty acids with chain length of C12:0-C16:0 are atherogenic, stearic acid is neutral, and oleic and polyunsaturated fatty acids have a lipid lowering effect Total saturated fatty acids ... found regarding total SFA (saturated fatty acids), and PUFA (polyunsaturated fatty acids) SFA were around 34% to 45% of total fatty acid methyl esters; cisPUFA, around 13% to 20% of total methyl esters ... samples of triplicates * Fatty acids less than 0.1%: C15:0, C17:0, C21:1 * SFA: saturated fatty acids * PUFA: polyunsaturated fatty acids * TFA: trans fatty acid* MUFA: monounsaturated fatty acids...

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Power converter control circuits for two mass vibratory conveying system with electromagnetic drive simulations and experimental results IEEE trans

Ngày tải lên : 03/01/2014, 19:16

... and transistor power converters II ELECTROMAGNETIC VIBRATORY ACTUATOR (EVA) All main types of vibratory actuators can be seen as two-mass systems The majority of them generate harmonic excitation ... for cases of phase angle control and switch-mode current control are presented Parameters of the real actuator and vibratory system are chosen Electrical and mechanical parameters of the EVA are ... of the above-mentioned vibratory actuators are shown in Fig The mathematical model of EVA is based on presentation in Figs 2 (a) and with details An electromagnet is connected to an ac source and...

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Tài liệu Báo cáo khoa học: Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-D-glyceric acid Selective inhibition by structure-based design docx

Ngày tải lên : 20/02/2014, 02:21

... used to further characterize the speciﬁc binding modes of these 1,3-BPGA analogues to the two trypanosomatid enzymes Materials and methods Sources of substrates, cofactors and inhibitors The synthesis ... codon of the T brucei gGAPDH gene; an antisense primer 5¢-CAGCCAAGCGCCTAGGGAGCGAGA AC-3¢, containing a BamHI site (underlined) and starting 31 nucleotides downstream of the stop codon The total volume ... catalysis The average isotropic temperature factor values for the main chain and all atoms of the 359 residues from ˚ ˚ each monomer are, respectively, 43.5 A2 and 43.8 A2 in ˚ ˚ ˚ monomer A, ...

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Báo cáo khoa học: Peptides from puriﬁed soybean b-conglycinin inhibit fatty acid synthase by interaction with the thioesterase catalytic domain pot

Ngày tải lên : 06/03/2014, 09:22

... format MAT, malonyl-CoA transacylase domain; KS, b-ketoacyl synthase domain; KR, b-ketoacyl reductase domain; DH, dehydratase domain; ER, b-enoyl reductase domain; ACP, acyl-carrier protein domain; ... Inactivation of hypothalamic FAS by C75 is linked to satiety and dramatic weight loss [15] because accumulation of the substrate malonyl CoA through the inhibition of FAS appears to inhibit the ... Cruz, CA, USA) Unless otherwise stated, all chemical reagents were from Sigma-Aldrich FAS activity assay FAS activity was assayed by a spectrophotometric method using a Synergy Microplate Reader...

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Báo cáo khoa học: Two L-amino acid oxidase isoenzymes from Russell’s viper (Daboia russelli russelli) venom with different mechanisms of inhibition by substrate analogs pdf

Ngày tải lên : 07/03/2014, 05:20

... (RVV)-7, a cytotoxin with phospholipase A2 (PLA2) activity [17] that also acts as a renal tubular necrosis factor [18] Empirical assay protocols for hemorrhage and PLA2 activity that are suitable ... combinations of OAB OAB, OAB NAT and OAB NATA were applied to L1 and L2, considering OAB as inhibitor (I1) and OAB, NAT and NATA as inhibitor (I2) In these experiments, the substrate concentration ... group and amidation of the carboxylate group in Trp result in a substrate analog N-acetyl-l-tryptophan amide (NATA) with neutralized charged groups, whereas N-acetyltryptophan (NAT) bears a carboxylate...

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Báo cáo khoa học: Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops docx

Ngày tải lên : 07/03/2014, 17:20

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