1 3 dipolar cycloadditions and 1 3 dipolar cycloreversions as steps in the ozonolysis of alkenes

Tài liệu Báo cáo khoa học: NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles doc

Ngày tải lên : 18/02/2014, 06:20

... complete assignment of 1H, 15 N and 13 C resonances of VpUcyt at 30 °C in buffer with 10 0 mm DPC-d38 was accomplished on the basis of a series of 3D NMR experiments recorded on uniformly 15 N- and 13 C-labelled ... amino acid residues 39 – 81 of VpU The dotted lines mark the theoretical average values of the downﬁeld shift of 13 Ca (top) and 13 CO (bottom) as well as of the upﬁeld shift of 1Ha resonances (middle) ... T47-Hb-Q 61- CH2c A50-CH3b-P75-CH2d G54-CH2a-W76-Ha H72-Hd-V78-Ha H72-Hd-V78-CH3c H72-He-V78-CH3c H72-He-L 81- Hc H72-He-L 81- CH3d 1. 205 4.458 4. 430 4. 430 1. 509 4.070 7 .33 2 7 .33 2 8.6 41 8.6 41 8.6 41 2 . 13 9; 1. 774...

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Báo cáo khoa học: Existence of novel b-1,2 linkage-containing side chain in the mannan of Candida lusitaniae, antigenically related to Candida albicans serotype A potx

Ngày tải lên : 17/03/2014, 03:20

... 4 .11 8 3. 956 3. 6 73 ND 3. 8 71 3. 738 5 .34 8 3. 932 3. 945 3. 6 93 ND 3. 860 3. 499 4.8 41 4 .14 8 3. 610 3. 567 3. 348 3. 914 3. 728 4.8 53 4.2 61 3. 655 3. 598 3. 389 3. 916 3. 756 5 .14 0 4.2 51 3. 887 3. 605 ND 3. 854 3. 7 31 ... 3. 7 31 5.262 4 .11 3 3.954 3. 667 ND 3. 866 3. 733 5 .34 0 3. 933 3. 944 3. 692 ND 3. 854 3. 780 4. 914 4 .39 9 3. 6 31 3. 589 3. 362 3. 916 3. 750 4.845 4.245 3. 690 3. 5 03 3 .39 5 3. 936 3. 715 5 .15 0 4.265 3. 898 3. 592 ... H -1 5.554 5.542 5 .37 3 5 .30 2 H-2 4. 210 4 .18 9 4.090 4 .10 0 5.286 5.2 61 5 .15 2 5. 233 4.099 4.087 4 .12 6 4.096 10 5 . 13 0 5 .12 1 4.065 4. 017 11 5 .10 4 4.029 12 5.0 93 3.997 13 5.074 4.008 14 15 16 17 18 19 ...

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Báo cáo y học: " HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain" doc

Ngày tải lên : 13/08/2014, 09:21

... http://www.retrovirology.com/content/2 /1/ 39 Testing Rev activity using reporters encoding the CAT gene within an intron The functional activity of the mutants was tested using the two reporter plasmids pDM 138 -RRE and pDM 138 -6xIIB ... Cross-activation of the Rex proteins of HTLV-I and BLV and of the Rev protein of HIV -1 and nonreciprocal interactions with their RNA responsive elements New Biol 19 89, 1( 3) : 31 8 -32 8 Hanly SM, Rimsky ... sites from the env gene [ 43, 44] In the plasmid pDM 138 -6xIIB the RRE sequence was replaced by six repeats of the IIB high affinity site for Rev binding allowing binding of six monomers [40] The Rev...

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Báo cáo y học: " Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections" pdf

Ngày tải lên : 09/08/2014, 08:23

... quantification of MMP mRNAs was performed using SYBR green real-time polymerase chain reaction (PCR) on the cDNAs obtained Assays for MMP -1, 2, -3, -7, -8, -9, -10 , -11 , -12 , - 13 , and -14 were performed ... volunteers and synovial fibroblasts from de-identified RA patients and OA patients were maintained in DMEM/F -12 containing 10 % FBS, 10 0 U/ml penicillin, and 10 0 μg of streptomycin All the fibroblast ... notably increased induction of TIMP -1, -2, and -3 mRNA by the Agr/Sar A deletion mutant (U 930 ) of the isogenic parent wildtype strain (U1) and the ATCC strain isolated from the synovium of a patient...

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Barriers to research utilization and research use among registered nurses working in the care of older people: Does the BARRIERS Scale discriminate between research users and non-research users on perceptions of barriers? potx

Ngày tải lên : 11/08/2014, 05:21

... 79% 70% 63% 50% 46% 41% 23% 2 .17 ± 0.66 57% 52% 37 % 30 % 23% 13 % 2.62 ± 0.58 81% 80% 67% 55% 43% 17 % 18 64% 40% 17 19 21 22 24 25 28 13 14 16 27 10 12 20 23 26 30 Page of 10 (page number not for ... written in English (n = 13 0) The amount of research information is overwhelming (n = 93) Rank order Total (n = 14 0) 11 15 29 2 .19 ± 0.56 89% 41% 39 % 33 % 30 % 28% 25% 19 % 2. 71 ± 0.52 88% 79% 70% 63% ... Innovations theory [8] The items in the instrument cover four domains of barriers: the nurse, the setting, the research, and the presentation In a review including 39 published articles and six theses...

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báo cáo khoa học: " Barriers to research utilization and research use among registered nurses working in the care of older people: Does the BARRIERS Scale discriminate between research users and non-research users on perceptions of barriers?" pptx

Ngày tải lên : 11/08/2014, 16:21

... 79% 70% 63% 50% 46% 41% 23% 2 .17 ± 0.66 57% 52% 37 % 30 % 23% 13 % 2.62 ± 0.58 81% 80% 67% 55% 43% 17 % 18 64% 40% 17 19 21 22 24 25 28 13 14 16 27 10 12 20 23 26 30 Page of 10 (page number not for ... written in English (n = 13 0) The amount of research information is overwhelming (n = 93) Rank order Total (n = 14 0) 11 15 29 2 .19 ± 0.56 89% 41% 39 % 33 % 30 % 28% 25% 19 % 2. 71 ± 0.52 88% 79% 70% 63% ... Innovations theory [8] The items in the instrument cover four domains of barriers: the nurse, the setting, the research, and the presentation In a review including 39 published articles and six theses...

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Development strategy for Petro Capital and Infrastructure Investment Joint Stock Company (Petroland) in the period of 2011-2015

Ngày tải lên : 27/03/2015, 13:56

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Báo cáo y học: "Hyaluronan modulates accumulation of hypoxiainducible factor-1 alpha, inducible nitric oxide synthase, and matrix metalloproteinase-3 in the synovium of rat adjuvant-induced arthritis model" potx

Ngày tải lên : 12/08/2014, 17:21

... 0 .11 2.50 ± 0 .11 b 9.55 ± 0.28 No-tr c 3D6d b 1. 40 ± 0 .11 a, b 2 .15 ± 0 .11 P

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Báo cáo y học: " Research In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques associated with Alzheimer''''s disease" doc

Ngày tải lên : 13/08/2014, 16:20

... -4 .19 2 -12 4 .1 -10 4. 41 Pose -12 2 .39 3 65 .18 4 -5.026 -7. 415 -12 3. 899 -97 .38 5 Pose -12 2. 31 75.752 -6.849 -7.294 -12 1 .12 4 -92.7 51 Pose -12 0.076 71. 516 -2.5 -2.5 -11 9.209 -95. 735 Pose -12 0. 037 75.257 ... -12 2 .39 3 65 .18 4 -5.026 -7. 415 -12 3. 899 -97 .38 5 Pose -12 2. 31 75.752 -6.849 -7.294 -12 1 .12 4 -92.7 51 Pose -12 0.076 71. 516 -2.5 -2.5 -11 9.209 -95. 735 Pose -12 0. 037 75.257 -2.5 -2.5 -11 8.7 21 -92. 915 6 ... Ile444), acyl binding pocket (ABP, Trp 233 , Phe288, Phe290, Phe292, Phe 330 , Phe3 31 ) and peripheral anionic subsite (PAS, Asp72, Tyr1 21, Ser122, Trp279, Phe3 31 , Tyr 334 ) are buried at the bottom of a 20...

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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf

Ngày tải lên : 18/02/2014, 04:20

... Nottingham, UK) The resulting double-stranded DNA was cloned in frame with VP16 MT1/MYC has a MYC tag between P 31 2 and T 31 3 in the hinge domain of MT1-MMP LLY570-573AAA MT1/MYC and G2A GRASP55F mutants ... 585–607) and MT5MMP (amino acids 6 23 645) ICDs MT1-MMP (VP16MT1 Y, VP16-MT1 LL, VP16-MT1 FRR, VP16-MT1 HGT, VP16-MT1 PRR, VP16-MT1 LLY, VP16-MT1 CQR, VP16-MT1 SLL, VP16-MT1 DKV), MT2-MMP (VP16-MT2 ... conﬁrming the important role of the LLY5 73 motif in the interaction between the protease and GRASP55 Interestingly, mutation of the LLY5 73 motif led to the detection of pro-MT1-MMP in the immunoprecipitate,...

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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is speciﬁcally induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf

Ngày tải lên : 21/02/2014, 01:21

... mgÆmL )1 of TOS was incubated with 1. 33 lgÆmL )1 GALA at 30 °C, pH 4.5 (McIlvain buffer) for 15 min, 30 min, h and 20 h, respectively The incubation was stopped by heating the samples for at 10 0 ... °C a-L -1, 3- Arabinofuranosidase activity in the GALA preparation was measured as described before [27], using 10 and 10 0 lL of the enzyme preparation (in duplicate) and incubation times of and h ... MALDI-TOF MS after incubation of mgÆmL )1 of potato, onion and soy arabinogalactan with 1. 33 lgÆmL )1 GALA at 30 °C, pH 4.5 (McIlvain buffer) for 15 min, 30 min, h and 20 h, respectively The incubation...

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Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States pdf

Ngày tải lên : 05/03/2014, 13:20

... weeks, the 6-month infant HIV infection rate was 1. 1% (0 .3% – 1. 8%) in the extended NVP Arm and 2.4% (1. 3% 3. 6%) in the placebo Arm (P = 0.048) • At infant randomization at age weeks, 29% of mothers ... MTCT was 14 .3% in sdNVP arm vs 14 .1% in ZDV arm at weeks (not significant, P = 0 .30 ) For breastfed infants only, MTCT was 12 .2% in sdNVP arm and 19 .6% in ZDV arm (P = 0. 03) Mashi Botswana20, 36 ... http://aidsinfo.nih.gov/guidelines on 12 /14 /2 012 EST Introduction (Last updated July 31 , 2 012 ; last reviewed July 31 , 2 012 ) Recommendations regarding HIV screening and treatment of pregnant women and...

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Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf

Ngày tải lên : 08/03/2014, 08:20

... exocytosis in 3T3L1 cells Biochem J 31 3 , 12 5 13 1 10 Cross, D.A.E., Alessi, D.R., Cohen, P., Andjelkovic, M & Hemmings, B.A (19 95) Inhibition of glycogen synthase kinase -3 by insulin-mediated protein kinase ... of GSK3 (using Li or SB- 415 286) appears to be sufﬁcient for inducing activation of GS in muscle and fat cells, and that inhibition of the kinase potentiates insulin action in muscle of insulin-resistant ... Biochem 270) 38 31 Results and discussion Effects of insulin, Li and SB- 415 286 on GSK3 activity As an initial starting point for our studies we investigated the effects of insulin, Li and the maleimide,...

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Investigation of au and in as solvents for the growth of silicon nanowires on si(1 1 1)

Ngày tải lên : 16/03/2014, 15:17

... thin oxide layer forms during insertion of the sample into the UHV chamber in spite of the preceding HF-dip There are hints in the literature [11 ] that deposition of gold onto a thin layer of ... take the surface tension of pure indium as an approximation which is 0.6 J/m2 at its melting point (15 7 1C) [ 13 ] As the surface tension of most liquids decreases in a nearly linear fashion with increasing ... following the effects of different diffusion coefﬁcients of gold and indium on silicon, the solubility of substrate atoms in the two metals, the surface tension of gold and indium and the surface...

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Báo cáo Y học: A polymer with a backbone of 3-deoxy-D-glycero -D-galacto -non-2ulopyranosonic acid, a teichuronic acid, and a b-glucosylated ribitol teichoic acid in the cell wall of plant pathogenic Streptomyces sp. VKM Ac-2124 pdf

Ngày tải lên : 17/03/2014, 10:20

... 4. 03 3.98 3. 88 3. 95 3. 55 4. 01 3. 80 3. 66 H-5¢ H-6 H-6¢ H-7 H-8 H-9 H-9¢ Polymer II (C) 1. 78 2.20 (D) 4.55 3. 31 3. 50 3. 38 3. 39 (E) 4.09 3. 97 3. 96 3. 81 4 .18 4 .17 4.09 (F) 4.66 3. 32 3. 50 3. 40 3. 43 ... 2 3% solutions in D2O at 30 °C with acetone (dH 2.225 dC 2 31 . 45) as the internal standard, and 80% H3PO4 as the external standard for 31 P NMR Presaturation of the HDO signal (1 s) was used in the ... (2J3 ,3 13 .0 Hz; J3,4 4.9 Hz) and 1. 78 (J3¢,4 12 .4 Hz) The 1D NMR spectra could be interpreted from the analysis of 2D homonuclear 1H, 1H COSY, TOCSY and ROESY spectra and 2D heteronuclear 1H, 13 C...

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PHYSICAL TECHNIQUES IN THE STUDY OF ART, ARCHAEOLOGY AND CULTURAL HERITAGE VOLUME 1 pdf

Ngày tải lên : 22/03/2014, 09:20

... 51 52 53 54 55 56 38 38 36 33 33 32 31 31 30 29 28 28 28 25 24 24 23 23 23 19 19 18 17 16 16 15 13 13 13 13 13 13 13 12 12 12 11 10 10 10 10 The Modern Museum 13 operated by the participants of ... 12 1 12 1 12 5 12 6 13 3 13 6 14 0 14 5 14 6 15 1 15 2 15 7 16 1 16 3 16 6 16 9 16 9 Chapter Egyptian Eye Cosmetics (Kohls): Past and Present Andrew D Hardy, R.I Walton, R Vaishnav, K.A Myers and M.R Power and ... The Modern Museum 31 REFERENCES [1] [2] [3] [4] [5] [6] [7] [8] [9] [10 ] [11 ] [12 ] [ 13 ] [14 ] [15 ] [16 ] [17 ] [18 ] [19 ] [20] [ 21] [22] [ 23] [24] [25] [26] [27] [28] [29] [30 ] [ 31 ] [32 ] [33 ] [34 ]...

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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx

Ngày tải lên : 23/03/2014, 07:20

... of caspase -1, caspase-8 and caspase -10 , and increase their expressions In turn, increased pro-caspase-8 is recruited to HIPPI–HIP -1 heterodimer and increases apoptosis The role of caspase -1 in ... together induce apoptosis [ 23, 24] Identiﬁcation of additional proteins such as Homer1c ⁄ Homer1 [ 31 ] , BAR ⁄ BFAR [32 ], RybP [33 ], BLOC1S2 [34 ] and apoptin [35 ] that interact with HIPPI further indicates ... Caspase-8 ? Normal Htt ? Pro-caspase Caspase1 Caspase Apoptosis Pro-caspase 2 Heterodimerization of HIPPI and HIP1 Recruitment of Pro-caspase Activation of caspase that leads to activation of...

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Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identiﬁed substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf

Ngày tải lên : 29/03/2014, 21:20

... used for cloning Plasmid Insert pGAD-CARP Full-length CARP CARP from 71 to 31 9 Full-length CARP 1 31 9 CARP from 30 to 31 9 CARP from 71 to 31 9 CARP from 10 2 to 31 9 CARP from 12 4 to 31 9 CARP from ... Richard I & Beckmann JS (19 96) Chromosome 15 -linked FEBS Journal 277 (2 010 ) 432 2– 433 7 ª 2 010 The Authors Journal compilation ª 2 010 FEBS 433 3 Regulation of CARP by calpain 3 10 11 12 L Laure et al limb-girdle ... before amino acid 71, the region of cleavage would be between amino acids 65 and 71 Considering the location of the N-terminal extremity of DNter2 on the structure of CARP and the presence of the...

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báo cáo hóa học: " Onset and persistence of person-perceived participation restriction in older adults: a 3-year follow-up study in the general population" pptx

Ngày tải lên : 18/06/2014, 19:20

... (0.76, 1. 72) 0.57 (0 .30 , 1. 10) 1. 14 (0.76, 1. 73) 0.57 (0 .30 , 1. 11) 1. 31 (0.87, 2.00) 0.69 (0 .35 , 1. 34 ) Social activities 1 2 3+ 1. 53 (1. 14, 2.06) 2.07 (1. 41, 3. 04) 1. 53 (1. 14, 2.06) 2.08 (1. 41, 3. 05) ... (44.9) 15 1 (55 .1) Any ( 1 aspect) Minimal (1 3 aspects) Moderate (4–6 aspects) Substantial (7 11 aspects) 16 60 (44.8) 12 50 (33 .7) 30 8 (8 .3) 10 2 (2.8) 18 74 (57.5) 13 22 (40.6) 433 ( 13 .3) 11 9 (3. 7) ... 2.05 (1. 42, 2.96) 1. 62 (1. 20, 2 .18 ) 2. 03 (1. 40, 2.95) Work 1 2 3+ 1. 24 (0.78, 1. 97) 1. 10 (0.60, 2. 03) 1. 23 (0.78, 1. 95) 1. 08 (0.59, 1. 98) 1. 33 (0. 83, 2 . 13 ) 1. 25 (0.67, 2 .32 ) Education 1 2 3+ 1. 14...

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báo cáo hóa học: " Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes" pdf

Ngày tải lên : 19/06/2014, 22:20

... http://www.jneuroinflammation.com/content/4 /1/ 12 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 Semenza GL: Hypoxia-inducible factor and the molecular physiology of oxygen homeostasis J Lab Clin Med 19 98, 13 1:207- 214 Semenza ... across the BBB to the sites of axonal injury in the brain [33 ,37 ] Both in vitro and in vivo findings suggest that hypoxia/ischemia-induced infiltration of monocytes and macrophages contributes to the ... Mutant HIF -1 probe HIF -1 C H +/+ HIF -1 +/Co C H Co 10 11 12 wt HIF -1 +/+ H H 13 14 HIF -1 shift HIF -1 HIF -1 - + HIF -1 antibody B) Luciferase activity units/mg protein (%) 30 0 250 * 200 15 0 10 0 50...

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