DNA vaccine and Application of DNA vaccine in “Fisheries” Photo Album by Activated User Photo Album by Activated User  DNA vaccine is DNA sequence used as a vaccine  This DNA sequence code for antigenic protein of pathogen  As this DNA inserted into cells it is translated to form antigenic protein. As this protein is foreign to cells, so immune response raised against this protein.  In this way, DNA vaccine provide immunity against that pathogen. Photo Album by Activated User [...]... Path Va ine cc IHN is an RNA stranded virus The genome codes for 6 different proteins are given Five are structural proteins and one is a non structural protein Must know which gene codes for the protein that is involved in the immunetic response It is the glyco protein spike on the outside of the virus, denoted by the G protein, that is the immunetic protein of the virus Insect G-gene into DNA plasmid... plasmid form Recombinant DNA Inject DNA vaccine into Fish G-gene construct shows good surface expression, which is believed to be a key feature to the effectiveness of the vaccine You also see a very heavy monocytic cell infiltrate, most likely white blood cells ie r e u Q ? s http://wikipedia.org Tom Christian Tonheim*, Jarl Bøgwald, Roy Ambli Dalmo ** What happens to the DNA vaccine in fish? 19 March... http://wikipedia.org Tom Christian Tonheim*, Jarl Bøgwald, Roy Ambli Dalmo ** What happens to the DNA vaccine in fish? 19 March 2008 http://www.bcic.ca/research-institutions/research-development http://www.immune.org.nz/print.asp?t=919 http:/ /dna -vaccine. net/ Many thanks to all of you! Trần Tuấn Anh Vũ Mạnh Công Nông Văn Cương Vi Đại Lâm Nguyễn Đức Thành Hoàng Đình Việt . DNA vaccine and Application of DNA vaccine in Fisheries Photo Album by Activated User Photo Album by Activated User  DNA vaccine is DNA sequence used as a vaccine  This DNA sequence. protein of pathogen  As this DNA inserted into cells it is translated to form antigenic protein. As this protein is foreign to cells, so immune response raised against this protein.  In. involved in the immunetic response. It is the glyco protein spike on the outside of the virus, denoted by the G protein, that is the immunetic protein of the virus. Insect G-gene into DNA plasmid