J Vet Sci (2002), 3(2), 123-133 JO U R N A L O F Veterinary Science Prevalence and Clinical Characterization of Gastric Helicobacter Species Infection of Dogs and Cats in Korea Cheol-Yong Hwang, Hong-Ryul Han* and Hwa-Young Youn Department of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea Received Dec 16, 2001 / Accepted May 16, 2002 ABSTRACT10) Th is s tu dy w as c arrie d o u t to e va lu ate th e pre va le n c e an d clin ica l c h ara cte riza tion s of g as tric Helicoba cter s pp in fe c tion o f d og s an d ca ts in Kore a Th e pre v ale n ce of Helicoba cter s pp in fe c tion o f gs an d c ats de te rm in e d by u re a se te st w as 78.4% an d 64%, respectively, although Helicoba cter g e n u s-s pe c ific P CR as sa y sh o w e d th at it w as 82.3% an d 84% U re a se m ap pin g re su lts ba se d o n u re as e te st sh o w e d th a t tota l po sitiv e te o f te ste d tis su e s fro m clin ica lly abn o rm al gs w a s s ign ific an tly h ig h e r th a n th at from c lin ic ally n orm a l d og s (p =0.0018; Od ds tio = 6.118; 95% Con fide n ce In te rv al = 1.96~19.103) Th e s e findings were consistent with the results of Helicoba cter ge n u s-sp e cific P CR a ss ay w h ich sh o w e d th a t p os itive te o f th e fu n du s (100%) an d th e a n tru m (100%) of clin ica lly abn o rm al d og s w a s s ign ifica n tly h igh e r th an th a t of sa me g as tric re gio n s o f c lin ica lly n orma l gs (77.5 an d 67.5% re sp e ctiv e ly ) In co m pa riso n of ga stric re gio n s be tw e e n c lin ica lly n orm a l d og s an d abn o rm al gs , po sitiv e te of u re as e te s t fo r th e fu n du s (100%) a n d bod y (90.9%) in clin ica lly a bn orm a l gs w as sig n ifica n tly h igh e r th an th at of a bn o rm al gs (72.5% a n d 57.5% re sp e c tive ly; p