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For example, use of fluorogenic probes in 5' nuclease assays may require licenses under U.S. Patent Nos. 6,214,979, 5,804,375, 5,210,015 and 5,487,972 owned by Roche Molecular Systems, Inc. and under U.S. Patent No. 5,538,848 owned by Applied Biosystems. Need More Information? Give Us A Call: Stratagene USA and Canada Order: (800) 424-5444 x3 Technical Services: (800) 894-1304 x2 Stratagene Japan K.K. Order: 03-5159-2060 Technical Services: 03-5159-2070 Stratagene Europe Order: 00800-7000-7000 Technical Services: 00800-7400-7400 www.stratagene.com • Top 25 downloads • Daily news feed • New product resources GET THE BIG PICTURE IN SCIENCE If you’re a scientist, the online version of Science puts a world of essential knowledge at your fingertips. And we’re now proud to announce the launch of our redesigned website, which makes it even easier to keep up with the latest breakthroughs, browse journal archives, or find career advice. 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GE15-05 www.sciencemag.org SCIENCE VOL 311 6 JANUARY 2006 5 CONTENTS CONTENTS continued >> NEWS OF THE WEEK How Young Korean Researchers Helped Unearth 22 a Scandal … … And How the Problems Eluded Peer Reviewers 23 and Editors Indian Scientist Slain in Surprise Attack 25 SCIENCE SCOPE 25 DuPont Settlement to Fund Test of Potential Toxics 26 NASA Terminates Gore’s Eye on Earth 26 New Particulate Rules Are Anything but Fine, 27 Say Scientists NIH Shrinks, NSF Crawls as Congress Finishes 28 Spending Bills How Saturn’s Icy Moons Get a (Geologic) Life 29 NEWS FOCUS A Very Good Year for Explosions 30 By Design, New Los Alamos Head 33 Hopes to Leave Big Imprint on Lab Judge Jones Defines Science— 34 and Why Intelligent Design Isn’t DEPARTMENTS 11 Science Online 12 This Week in Science 16 Editors’ Choice 18 Contact Science 19 NetWatch 21 Random Samples 35 Newsmakers 102 Information for Contributors 104 New Products 105 Science Careers COVER NASA Spitzer Space Telescope false-color image of a portion of the Perseus spiral arm of the Milky Way. Bright regions are clusters of newly formed stars. Recent observations with the National Radio Astronomy Observatory Very Long Baseline Array yielded the distance to a newly formed star (in the bright cluster toward the lower left) with unprecedented accuracy and precisely located the Perseus spiral arm. See page 54. Image: C. E. Woodward, G. Ruch, T. J. Jones EDITORIAL 15 New Year, New Look, Old Problem by Donald Kennedy 30 CREDIT (BOTTOM LEFT): CAMERON SLAYDEN LETTERS Editorial Expression of Concern D. Kennedy 36 Revamping NIH Study Sections J. Lenard Clarifications on miRNA and Cancer G. Ruvkun Coastal Vegetation and the Asian Tsunami F. Dahdouh-Guebas and N. Koedam Response F. Danielsen et al. BOOKS ET AL. Beam The Race to Make the Laser 39 J. Hecht, reviewed by C. Webb Warped Passages Unraveling the Mysteries of 40 the Universe’s Hidden Dimensions/Unravelling the Universe’s Hidden Dimensions L. Randall, reviewed by J. D. Wells POLICY FORUM Peer Review at NIH 41 T. Scarpa PERSPECTIVES Complexities of Coral Reef Recovery 42 O. Hoegh-Guldberg >> Report p. 98 A Different Kind of Croc 43 J. M. Clark >> Report p. 70 Triangulating the Galaxy 44 J. J. Binney >> Report p. 54 A New Molecule to Brighten the Mood 45 T. Sharp >> Report p. 77 Volume 311, Issue 5757 Evolutionary Biology Get the insider’s perspective on the editorial featured in this issue of Science…interviews with researchers on their extraordinary findings on how evolution proceeds and an insightful commentary by Donald Kennedy—Science’s Editor-in-Chief. FREE ACCESS to this issue until 31 March 2006 ProducedbyBiocompare and Science Watch the Breakthrough of the Year video at www.sciencemag.org/sciext/btoy2005 Science’s 2005 Breakthrough of the Year www.sciencemag.org SCIENCE VOL 311 6 JANUARY 2006 7 CONTENTS continued >> SCIENCE EXPRESS www.sciencexpress.org ARCHAEOLOGY Early Maya Writing at San Bartolo, Guatemala W. A. Saturno, D. Stuart, B. Beltrán An early Maya temple contains hieroglyphics dating to about 250 BC, implying that writing appeared in Maya societies shortly after it emerged elsewhere in the New World. 10.1126/science.1121745 ASTRONOMY Cosmological Magnetic Field: A Fossil of Density Perturbations in the Early Universe K. Ichiki, K. Takahashi, H. Ohno, H. Hanayama, N. Sugiyama Scattering of photons off electrons in the primordial universe generated magnetic fields strong enough to seed magnetic fields seen in galaxies and galaxy clusters today. 10.1126/science.1120690 ECOLOGY BREVIA: Post-Wildfire Logging Hinders Regeneration and Increases Fire Risk D. C. Donato et al. Unexpectedly, by disturbing the soil, salvage logging after a fire in a Douglas fir forest reduced conifer seedling regeneration by 73% and also added kindling to the forest floor. 10.1126/science.1122855 ASTRONOMY BREVIA: The Orbital Period of the Ultraluminous X-ray Source in M82 P. Kaaret, M. G. Simet, C. C. Lang Gas supplied from a bloated star orbiting around a massive black hole, a highly transient system that is rarely observed, may periodically brighten a luminous x-ray source. 10.1126/science.1121067 CONTENTS TECHNICAL COMMENT ABSTRACTS ATMOSPHERIC SCIENCE Comment on “A Hydrogen-Rich Early Earth Atmosphere” 38 D. C. Catling full text at www.sciencemag.org/cgi/content/full/311/5757/38a Response to Comment on “A Hydrogen-Rich Early Earth Atmosphere” F. Tian, O. B. Toon, A. A. Pavlov full text at www.sciencemag.org/cgi/content/full/311/5757/38b REVIEW PSYCHOLOGY When Does “Economic Man” Dominate Social Behavior? 47 C. F. Camerer and E. Fehr BREVIA APPLIED PHYSICS Two-Way Laser Link over Interplanetary Distance 53 D. E. Smith et al. By returning a laser signal beamed from Earth, the Messenger spacecraft signaled its position to within 20 centimeters, thus testing an advanced means of space communication. REPORTS ASTRONOMY The Distance to the Perseus Spiral Arm in the Milky Way 54 Y. Xu, M. J. Reid, X. W. Zheng, K. M. Menten Radio parallax measurements provide an accurate distance to a star cluster in the Perseus spiral arm and show that this cluster is rotating differently than expected for the Milky Way. >> Perspective p. 44 PHYSICS Quantum Dynamics of a d-Wave Josephson Junction 57 T. Bauch et al. A high-temperature superconducting device shows macroscopic quantum effects required for an inherently quiet and stable qubit, which is needed for quantum information storage. CHEMISTRY Quantum Deconstruction of the Infrared Spectrum of CH 5 + 60 X. Huang et al. Calculations based on a quantum mechanical potential energy surface reveal specific molecular motions that comprise the experimental CH 5 + vibrational spectrum. OCEAN SCIENCE Planktonic Foraminifera of the California Current 63 Reflect 20th-Century Warming D. B. Field et al. Variation in plankton preserved in sediments shows that the Santa Barbara basin has become warmer during the late 20th century than it was at any time during the past 1400 years. W. A. SATURNO ET AL. Introducing Rosetta Elucidator ® system. It’s a flexible, scalable solution for managing and analyzing large volumes of proteomics data. Powerful and reliable algorithms enable differential protein expression analysis so you can identify and validate potential biomarkers during drug development. Industry-leading tools manage terabytes of data and workflows improve productivity and focus research efforts. The result is an integrated bioinformatics platform that helps you optimize your organization’s drug discovery and development process. Find what you’re looking for today. Go to WWW.ROSETTABIO.COM/ELUCIDATOR for more details. Copyright © 2005-2006 Rosetta Inpharmatics LLC. All rights reserved. Elucidator and the Rosetta Biosoftware convergence icon are registered trademarks of Rosetta Inpharmatics LLC. It’s here. . co-evolutionary pressures. 6 JANUARY 2006 VOL 311 SCIENCE www.sciencemag.org www.sciencemag.org SCIENCE VOL 311 6 JANUARY 2006 13 This Week in Science Depression, Serotonin, and p11 Serotonin. parrotfish. www.cellsciences.com www.cellsciences.com cell sciences Cell Sciences 480 Neponset Street, Bldg. 12A Canton, MA 02021 USA Tel: 781 828-0610 Fax: 781 828-0542 email: info@cellsciences.com 888. Kennedy Science s Editor-in-Chief. FREE ACCESS to this issue until 31 March 2006 ProducedbyBiocompare and Science Watch the Breakthrough of the Year video at www.sciencemag.org/sciext/btoy2005 Science s