[...]... either of difficulty falling asleep or maintaining sleep, or of poor quality of sleep However, the presence of the complaint of unsatisfactory sleep is not sufficient for the diagnosis of insomnia in its own right It should also be a source of marked distress for the patient, and it should interfere with his/her ordinary activities in daily living This prevents mistaking insomnia for just a symptom of another... medical students and clinicians of various disciplines who want to get an overall grasp of the clinical pharmacology of sleep This volume includes contributions from a wide range of authors, many of whom are world-recognized authorities in their field Chapters in this volume deal with a range of topics, including, among others, the pharmacological treatment of insomnia, sleep disturbance in anxiety disorders,... Potential action of melatonin in insomnia Sleep 26: 1058–1059 70 Kisiroglu C, Guilleminault C (2004) Twenty minutes versus forty-five minutes morning bright light treatment on sleep onset insomnia in elderly subjects J Psychosom Res 56: 535–542 Clinical Pharmacology of Sleep Edited by S.R Pandi-Perumal and J.M Monti ¨ “ 2006 Birkhauser Verlag/Switzerland Neuropharmacology of obstructive sleep apnea and... Grunstein Sleep and Circadian Research Group, Woolcock Institute of Medical Research; and Sleep Investigation Unit, Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, NSW 2050, Australia Introduction Obstructive sleep apnea (OSA) and other forms of sleep- disordered breathing including central sleep apnea (CSA) are amongst the most common sleep. .. Manual (ICSD) [33] of patients presenting in sleep clinics, and found that in 6.2 % of those individuals the sleep problem was primarily due to inadequate sleep hygiene, and sleep hygiene contributed to sleeping problems in 34.2 % of the patients [34] 4 K.L Lichstein et al Diathesis-stress model A multi-factor model [35] contends that individuals may be predisposed to experience sleeping difficulties,... Benzodiazepines of long and short elimination half-life and the risk of hip fracture J Am Med Assoc 262: 3303–3307 7 Ancoli-Israel S, Roth T (1999) Characteristics of insomnia in the United States: results of the 1991 National Sleep Foundations Survey I Sleep 22: 347–353 8 Leger D, Guilleminault C, Dreyfus JP, Delahaye C, Paillard M (2000) Prevalence of insomnia in a survey of 12,778 adults in France J Sleep. .. between good and poor sleepers J Abnorm Psychol 72: 255–264 23 Bonnet MH, Arand DL (1997) Hyperarousal and insomnia Sleep Med Rev 1: 97–108 24 Harvey A (2000) Pre -sleep cognitive activity: A comparison of sleep- onset insomniacs and good sleepers Br J Clin Psychol 39: 275–286 25 Lichstein KL, Rosenthal TL (1980) Insomniacs’ perceptions of cognitive versus somatic determinants of sleep disturbance J Abnorm... Treatment of late-life insomnia Sage, Thousand Oaks, CA, 167–184 30 Hauri P (1977) The sleep disorders: current concepts Scope Publications, Kalamazoo 31 Riedel BW (2000) Sleep hygiene In: KL Lichstein, CM Morin (eds.): Treatment of latelife insomnia Sage, Thousand Oaks, 125–146 32 Stepanski EJ, Wyatt JK (2003) Use of sleep hygiene in the treatment of insomnia Sleep Med Rev 7: 215–225 33 American Sleep. .. past decades, sleep research has seen enormous progress Numerous discoveries have been described in a wealth of papers of ever increasing size and complexity These publications have become difficult to follow not only because of their number, but also because they have been published specialty journals that are not easily accessible The clinical pharmacology of sleep is a fascinating field of medical science... work and quality of life [28], and, although chronic insomnia warrants treatment, in the majority of cases is often under-treated [28] Traditional epidemiological studies of insomnia provide valid but fairly rudimentary information regarding the presence, frequency, duration and evolution of sleep problems [44] Polysomnography provides an accurate measure of sleep latency and total sleep time, but it . emergence of clinical sleep medicine marked by the establishment of the harbinger Stanford Sleep Disorders Clinic in the mid 1970s, offspring sleep disor- ders. choose their clinical subject matter as it relates to their interest in specific conditions and their clinical pharmacology. Clinical Pharmacology of Sleep is