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Recruitment of a postdoctoral research fellow (12 months) Employer Sorbonne University (LabEx MiChem) Location Paris, France Gross salary 33 36 k€year upon experience Discipline Polymer Chemistry Mac.
Recruitment of a postdoctoral research fellow (12 months) Employer: Sorbonne University (LabEx MiChem) Location: Paris, France Design of thermoresponsive hybrid nanoparticles for biomedical applications Background Amphiphilic block copolymer assemblies have been widely investigated as drug delivery vehicles for biomedical applications In the past decade, the development of controlled radical polymerization techniques and the polymerization induced self-assembly (PISA) process have provided straightforward synthetic tools to access a variety of self-assembled stimuliresponsive nanoparticles (NPs) Gross salary: 33-36 k€/year upon experience In the framework of the LabEx MiChem, a collaborative project has been proposed between the Institut Parisien de Chimie Moléculaire (IPCM) and the Discipline: laboratory of PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX Polymer Chemistry (PHENIX), two complementary partners in the Labex MiChem The polymer Macromolecular chemistry team of IPCM at Sorbonne University (SU), one of the pioneering engineering team in the development of the PISA technique, has been developing new Hybrid synthesis strategies to synthesize worm-like NPs directly in water using PISA1–4 while the inorganic colloids team of PHENIX (SU) possesses solid expertise in the field Organization type: of magnetic nanoparticles (MNPs) synthesis and characterization, recently Academia applied in the biomedical field.5–7 Job type: Postdoc Duration: 12 months, starting before December 2019 The current project targets the design of novel thermosensitive magnetic filomicelles by PISA and their application to drug delivery Indeed, it was evidenced in the literature that such anisotropic NPs presented enhanced drug-delivery along with an increased blood circulation time Furthermore, the presence of such MNPs within thermosensitive NPs can provide targeting and remote drug delivery properties to the designed drug delivery system (DDS) Required qualifications: A PhD in Polymer Chemistry or any related field with experience in macromolecular engineering using controlled radical polymerization (CRP) will be preferred Alternatively, a strong background in the synthesis and characterization of thermosensitive polymers or hybrids would be a major asset for the success of the project The applicant should be open to work at the interface of polymer chemistry, inorganic chemistry and biochemistry A strong command of written and spoken English is recommended Good communication, laboratory and organizational skills Application: Curriculum Vitae // List of publications // References from two people All documents must be sent by e-mail to both contacts below Franỗois Stoffelbach (francois.stoffelbach@sorbonne-universite.fr) (IPCM) and Christine Mộnager (christine.menager@sorbonne-universite.fr) (PHENIX) Sorbonne University / Campus Pierre & Marie Curie, place Jussieu, 75005 PARIS – FRANCE REFERENCES: (1) Rieger, J Macromol Rapid Commun., 2015, 36, 1458 (2) Mellot, G et al Macromolecules, 2018, 51, 10214 (3) Mellot, G et al Angew Chemie - Int Ed., 2019, 58, 3173 (4) Biais, P et al Polym Chem., 2018, 9, 4483 (5) Cazares-Cortes, E et al Nanomaterials, 2018, 8, 850 (6) Cazares-Cortes, E et al ACS Appl Mater Interfaces, 2017, 9, 25775 (7) Griffete, N et al Nanoscale, 2015, 7, 18891