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BLOOD CELL –
AN OVERVIEW OF STUDIES
IN HEMATOLOGY
Edited by Terry E. Moschandreou
Blood Cell – An Overview of Studies in Hematology
http://dx.doi.org/10.5772/2979
Edited by Terry E. Moschandreou
Contributors
Gökhan Cüce, Tahsin Murad Aktan, Mahmoud Rafea, Serhiy Souchelnytskyi, Filip Cristiana,
Zamosteanu Nina, Albu Elena, Ambreen Shaikh, Deepa Bhartiya, Moneer Faraj, Nihaya Salem,
Junko Takahashi, Akiko Takatsu, Masaki Misawa, Hitoshi Iwahashi, Osamu Hayashi,
Karen A. Selz, Terry E. Moschandreou, Youngchan Kim, Kyoohyun Kim, YongKeun Park,
Hisham Mohamed, A.B. Shrivastav, K.P. Singh, S. Druyan, Kikuji Yamashita, Clement E. Zeh,
Collins O. Odhiambo, Lisa A. Mills, Nuri Mamak, İsmail Aytekin
Published by InTech
Janeza Trdine 9, 51000 Rijeka, Croatia
Copyright © 2012 InTech
All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license,
which allows users to download, copy and build upon published articles even for commercial
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Notice
Statements and opinions expressed in the chapters are these of the individual contributors and
not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy
of information contained in the published chapters. The publisher assumes no responsibility for
any damage or injury to persons or property arising out of the use of any materials,
instructions, methods or ideas contained in the book.
Publishing Process Manager Sandra Bakic
Typesetting InTech Prepress, Novi Sad
Cover InTech Design Team
First published September, 2012
Printed in Croatia
A free online edition of this book is available at www.intechopen.com
Additional hard copies can be obtained from orders@intechopen.com
Blood Cell – An Overview of Studies in Hematology, Edited by Terry E. Moschandreou
p. cm.
ISBN 978-953-51-0753-8
Contents
Preface IX
Section 1 Main Concepts 1
Chapter 1 Platelets 3
Gökhan Cüce and Tahsin Murad Aktan
Chapter 2 Rediscovering Red Blood Cells:
Revealing Their Dynamic Antigens Store
and Its Role in Health and Disease 13
Mahmoud Rafea and Serhiy Souchelnytskyi
Chapter 3 Homocysteine in Red Blood Cells Metabolism –
Pharmacological Approaches 31
Filip Cristiana, Zamosteanu Nina and Albu Elena
Chapter 4 Pluripotent Stem Cells in Bone Marrow and Cord Blood 69
Ambreen Shaikh and Deepa Bhartiya
Chapter 5 C-Reactive Protein 89
Moneer Faraj and Nihaya Salem
Chapter 6 Whole Blood RNA Analysis, Aging and Disease 101
Junko Takahashi, Akiko Takatsu,
Masaki Misawa and Hitoshi Iwahashi
Chapter 7 Proliferation and Differentiation of Hematopoietic Cells
and Preservation of Immune Functions 119
Osamu Hayashi
Chapter 8 Spontaneous Alternation Behavior
in Human Neutrophils 147
Karen A. Selz
Chapter 9 RBC-ATP Theory of Regulation
for Tissue Oxygenation-ATP Concentration Model 155
Terry E. Moschandreou
VI Contents
Section 2 Measurement of RBC Deformability and Microfluidics
Technology for Cell Separation 165
Chapter 10 Measurement Techniques for Red Blood Cell Deformability:
Recent Advances 167
Youngchan Kim, Kyoohyun Kim and YongKeun Park
Chapter 11 Use of Microfluidic Technology for Cell Separation 195
Hisham Mohamed
Section 3 Applications in Haematology 227
Chapter 12 Tigers Blood: Haematological and Biochemical Studies 229
A.B. Shrivastav and K.P. Singh
Chapter 13 Ascites Syndrome in Broiler Chickens
– A Physiological Syndrome Affected by Red Blood Cell 243
S. Druyan
Chapter 14 The Effects of the Far-Infrared Ray (FIR)
Energy Radiation on Living Body 271
Kikuji Yamashita
Chapter 15 Laboratory Reference Intervals in Africa 303
Clement E. Zeh, Collins O. Odhiambo and Lisa A. Mills
Chapter 16 Principles of Blood Transfusion 321
Nuri Mamak and İsmail Aytekin
Preface
The editor has incorporated scientific contributions from a diverse group of leading
researchers in the field of hematology and related blood cell research. This book aims
to provide an overview of current knowledge pertaining to our understanding of
hematology. The main subject areas will include blood cell morphology and function,
the pathophysiology and genetics of hematological disorders and malignancies, blood
testing and typing, and the processes governing hematopoiesis. Blood cell physiology,
biochemistry and blood flow are covered in this book.
This text is designed for hematologists, pathologists and laboratory staff in training and
in practice. Topics include platelets, whole blood RNA analysis, C-reactive protein,
pluripotent stem cells, proliferation and differentiation of hematopoietic cells,
homocysteine in red blood cells metabolism: pharmacological approaches, measurement
techniques for red blood cells deformability, spontaneous alternation behaviour in
human neutrophils, microfluidics technology for cell separation, effects of far infrared
radiation on living body, laboratory reference intervals in Africa, RBC-ATP biochemistry
and modelling, dynamics of RBC and antigens, transfusion principles, haematological
and biochemical studies in tigers and ascites syndrome in broiler chickens.
The work presented in this book will be of benefit to medical students and to
researchers of hematology and blood flow in the microcirculation. This book is written
primarily for those who have some knowledge of chemistry, biochemistry and general
hematology. The authors of each section bring a strong clinical emphasis to the book.
I am greatly indebted to many individuals who helped in the preparation of this book.
Those whom I wish especially to thank for their help with this edition include Drs. Dan
Goldman and Khoa Nguyen. I am also indebted to Dr. Jiandi Wan, who gave permission
to use the referenced figure in the chapter contributed by the editor. I also would like to
thank all those who took the time to email me offering helpful criticisms and
suggestions. This includes Ms. Sandra Bakic, publishing process manager at InTech.
Dr. Terry E. Moschandreou
University of Western Ontario, Middlesex College,
London, Ontario,
Canada
. BLOOD CELL –
AN OVERVIEW OF STUDIES
IN HEMATOLOGY
Edited by Terry E. Moschandreou
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Blood Cell – An Overview of Studies in Hematology
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