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A textbook of modern toxicology
[...]... depth of coverage of each topic represents that chapter author’s judgment of the amount of material appropriate to the beginning level as compared to that appropriate to a more advanced course Thanks to all of the authors and to the students and faculty of the Department of Environmental and Molecular Toxicology at North Carolina State University and to Carolyn McNeill for much word processing Particular... physical properties of a chemical and toxicity and, particularly, the use of such relationships as predictors of toxicity 5 Biomathematics and statistics relate to many areas of toxicology They deal with data analysis, the determination of significance, and the formulation of risk estimates and predictive models 6 Epidemiology as it applies to toxicology, is of great importance as it deals with the relationship... Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC Meyer, Sharon A. , Department of Toxicology, University of Louisiana, Monroe, LA Rose, Randy L., Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC Selgrade, MaryJane K., United States Environmental Protection Agency, Research Triangle Park, NC Shea, Damian, Department... into the actual teaching process as well as the subject matter of their areas of specialization At North Carolina State University, we continue to teach a course in general toxicology that is open to graduate students and undergraduate upperclassmen In addition, in collaboration with Toxicology Communications, Inc., of Raleigh, North Carolina, we present an accelerated short course at the same level... rather than being use classes All of these groups of chemicals are discussed in detail in Chapter 5 1.4 MOVEMENT OF TOXICANTS IN THE ENVIRONMENT Chemicals released into the environment rarely remain in the form, or at the location, of release For example, agricultural chemicals used as sprays may drift from the point of application as air contaminants or enter runoff water as water contaminants Many... Research Triangle Park, NC Hodgson, Ernest, Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC LeBlanc, Gerald A. , Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC Leidy, Ross B., Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC Levi, Patricia E., Department... chemicals is one of the applied roles of comparative toxicology 2 Clinical drugs are properly the province of pharmaceutical chemistry and pharmacology However, toxic side effects and testing for them clearly fall within the science of toxicology 3 Drugs of abuse are chemicals taken for psychological or other effects and may cause dependence and toxicity Many of these are illegal, but some are of clinical... such aspects of medicine as forensic medicine, clinical toxicology, pharmacy and pharmacology, public health, and industrial hygiene Toxicology also contributes in an important way to veterinary medicine, and to such aspects of agriculture as the development and safe use of agricultural chemicals The contributions of toxicology to environmental studies has become increasingly important in recent years... of North Carolina at Chapel Hill, Chapel Hill, NC Bonner, James C., National Institute of Environmental Health Sciences, Research Triangle Park, NC Branch, Stacy, Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC Cope, W Gregory, Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, NC Cunny, Helen, Bayer Crop... Many of these chemicals are susceptible to fungal or bacterial degradation and are rapidly detoxified, frequently being broken down to products that can enter the carbon, nitrogen, and oxygen cycles Other agricultural chemicals, particularly halogenated organic compounds, are recalcitrant to a greater or lesser degree to metabolism by microorganisms and persist in soil and water as contaminants; they may . Toxicology North Carolina State University A JOHN WILEY & SONS, INC., PUBLICATION A TEXTBOOK OF MODERN TOXICOLOGY THIRD EDITION A TEXTBOOK OF MODERN TOXICOLOGY THIRD. implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials.