... are also used as aromatics. Because of their pharmacological e ect, alkyl nitrites are being abused as uncontrolled inhalant drugs and causing a social problem [4]. Although there are many reports ... headspace (HS)-gas chromatography (GC) and liquid-liquid extraction-GC are presented. Determination of isobutyl nitrite in aqueous solution by headspace-GC Reagents and their pr...
... concentrations of DAEMS are spiked into blank serum specimens containing a xed amount of DAEMO (IS) each and extracted as described before. Since the base peaks of DAEMS and DAEMO (IS) equally appear ... biofluids by gas chromatography-mass spectrometry and liquid- liquid-solid phase-transfer-catalyzed pentafluorobenzylation. J Anal Toxicol 23:86–93 11) Black RM, Read RW (1998...
... EI mass spectra of ∆ 9 -THC, CBD, CBN and 5α-cholestane. GC analysis of cannabinoids in plant specimens 190 Cannabinoids and their metabolites GC/MS analysis of ∆ 9 -THC-11-oic acid in urine ... resin of the cannabis plant. Since the main component of cannabis, ∆ 9 -tetrahydrocannabi- nol ( ∆ 9 -THC), has various psychopharmacological e ects including hallucination, the...
... 8) Matsubara K, Fukushima S, Akane A et al. (1992) Increased urinary morphine, codeine and tetrahydropapavero- line in Parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine therapy: a possible ... patient, several grams of an opiate do occasionally not cause death. Toxic and fatal concentrations 204 Morphine and its analogues As a result of analysis of 203 fatal c...
... methemoglobinemia be- comes severe, it causes cyanosis, headache, easy fatigability, respiratory and conciousness dis- turbances and nally death. e fatal methemoglobinemia is rare, but fatal ones a ... Various known amounts of nitrate and a xed amount of IS are added to blank specimens and processed in the same way to construct a calibration curve. e peak area ratio...
... of his ingestion and death. In addi-
tion, the ratios of cocaine to BE in blood and in the brain, and the brain-to-blood ratios of
cocaine and BE were compared with those described in literature ... mass spectra of the authentic cocaine, EME and BE a er derivatization.
Setting up of cuto values are very common in USA and Europe as a part of QC ( quality...
... commercially avail-
able.
ii. Preparation
• Pentazocine and dextromethorphan solutions: the drugs are separately dissolved in appro-
priate amount of methanol; a 10–20 µL aliquot was added to 1 mL of ... the calibration curve, which is composed of pen-
221
tazocine concentration in the horizontal axis and peak area ratio of pentazocine to IS in the
vertical axis. e p...
... digestive tract is rapid and distinct visual hallucination takes place
45 min–1 h a er oral intake of about 20 µg of LSD [1]. e hallucination becomes most marked
2–3 h a er the intake and lasts ... powerful hallucinogenic
drugs of abuse. LSD was explosively abused in U.S .A. in the latter half of the 1960s. In Japan,
the amount of seizure of LSD is much smaller...
... H, Nakajima K, Nishikawa M et al. (1991) Determination of methamphetamine and amphetamine
in urine by headspace gas chromatography/mass spectrometry. Anal Sci 7:19–22
25) Shima N, Kamata T, ... hyperthermia, rhabdomyolysis, acute renal failure, dis-
seminated intravascular coagulation and death [19, 20]. A detailed review by Kalant [16] re-
vealed that 87 MDAs-related fatalities we...