... VO
2
is abnormally low in patients with lactic acidosis due to biguanide intoxication. This finding is in line
with the hypothesis of inhibited mitochondrial respiration and consequent hyperlactatemia.
Introduction
Metformin ... distribution, and reproduction in
any medium, provided the original work is properly cited.
Research
Oxygen consumption is depressed...
... issues
jointly; that is, to investigate plasma homocysteine levels
in patients with MS and depression.
Accordingly, the present study was designed in order to
assess Hcy plasma levels in MS patients ... purposes)
Discussion
The present study addressed the issue of Hcy metabolism
in MS and investigated whether Hcy levels are related to
depression in this disease. It is...
... YG, Christen WG, Foster SC: Correlation of metal-
loproteinase-2 and -9 with proinflammatory cytokines inter-
leukin-1β, interleukin-12 and the interleukin-1 receptor
antagonist in patients with ... inflammation,
resulting in fibrosis. MMP-9 can trigger inflammation
directly, by tissue destruction, or indirectly, by generation of
an inflammatory signal or recruitment of inflammatory...
... analysis, analyzed
the data, and contributed to the writing of the article. PB put
together the data, supervised the laboratory examinations,
analyzed the data, and contributed to the writing ... presented with a chronic
granulomatous disease.
All the patients included in this study had blood CD19
+
CD3
-
B-lymphocyte counts above 1% of peripheral blood lym-
phocytes. The CVID pati...
... the
incidence of extrapyramidal AEs may vary among the
atypical antipsychotics [13]. Atypical long-acting antipsy-
chotic therapy, a relatively new treatment modality in
man y sys tems of care, is ... baseline by visit and discontinuation status.
Patients included in this analysis were those who had 24 months of data and had all nine visits and at least one RLAT injection record in...
... baseline dis-
ease characteristics, symptomatology, as well as the
scales used to measure symptoms. While these data may
be hypothesi s-generating, the timing of improvement of
symptom domains ... and/or anxiolytics before study
entry was not established. Therefore, improvements
seen in this analysis may be due in part to noncompli-
ance with previous medications. Additionally, d...
... piratory fitness [14], and poor living conditions cer-
tainly contribute to the finding that these patients,
including those on antipsychotics, may have a higher
risk to develop metabolic syndrome ... that
changes in metabolic parameters in patients treated with
antipsychotics may, in part, be genetically determined
[17].
MetS is characterized by the coincidence of hyperten-...
... from nine healthy subjects, eleven
IPF patients and nine EP patients. We examined the
expression of 42 different cytokines in EBC using a cyto-
kine assay method. The cytokine and chemokine profil-
ing ... T,
Nakanishi M, Yamagata T, Minakata Y, Ichinose M: Airway cytokine
expression measured by means of protein array in exhaled breath
condensate: correlation with physiologic proper...
... obtained BMPR2 mutations in 86.4% of
HPAH patients with a positive family history and in
14.4% of patients with apparently sporadic disease. Only
in 3 out of 22 famili es with confir med HPAH (13.6%)
no ... gene.Wehaveexcludedthemfromgenotype-
phenotype analysis to reduce the risk of misclassification
as has been described before [15]. Interestingly, mean
age at diagnosis i...