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Báo cáo y học: " Assessment and histological analysis of the IPRL technique for sequential in situ liver biopsy" ppsx

Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx

Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx

... However, the mechanistic roles of several of these residues are not described well and there is no example of mutational analysis of all of these residues in the sameenzyme.To obtain an insight into ... circulans, whereas it may be mutated toasparagine without loss of activity in other family 18 chitinases [28,30]. Preliminary results of a comparativestudy of available structures of family 18 chitinases ... mutation toglutamate or alanine that was observed in this study and previous studies on other family 18 chitinases [20,26,28–30]. Mutation of this residue to aspartate in other family 18 chitinases...
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Báo cáo khoa học: Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p pptx

Báo cáo khoa học: Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p pptx

... localization and I. Birschmann et al. Domain function of Pex1p and Pex6p FEBS Journal 272 (2005) 4758 ê 2004 FEBS 57 Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p Ingvild ... assigned their corresponding binding sites and elucidated the importance of ATP-binding and -hydrolysis of Pex1p and Pex6p for their interaction. We show that the interaction of Pex1p and Pex6p ... analysis revealed the presence of Pex6p in the precipitate of full-length Pex1p ProtA and also the presence of Pex1p in the full-length Pex6p ProtA-precipitate(Fig. 1C,D). These data confirm the in vivo interaction of...
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Báo cáo y học: "Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis" pps

... phenotypic analy-sis of such membrane DC subsets is now necessary, and willoffer insight into the migratory pathway and functional activi-ties of distinct DC subsets in chronic synovitis. Finally, ... volunteersEnumeration of dendritic cell subsets in various arthritides and healthy volunteers. Plasmacytoid dendritic cells (pDCs) and myeloid dendritic cells (mDCs) are significantly decreased in rheumatoid arthritis ... number of cells (ì104/ml) in rheumatoid arthritis and psoriatic arthritis peripheral blood and matched synovial fluidWhite blood cells Myeloid dendritic cells Plasmacytoid dendritic cellsRheumatoid...
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Báo cáo y học: " Genome-wide comparative analysis of the Brassica rapa gene space reveals genome shrinkage and differential loss of duplicated genes after whole genome triplicatio" potx

... syn-teny in the uncovered and/ or the scattered genome regions.Rearrangement of the B. rapa genome Comparison of the genomes of Br and At allows insight into the origin and evolution of the Brassica ... the Bo and Bna genomesbut absence of this peak in the Br genome and between the other Brassica genomes strongly supports the hypothesisthat duplicated genes from the 3R event were lost in the ... be driven by the deletion of redundant genome components at the level of both the chromosome and the gene. A genome- wide synteny comparison between Br and At revealed that some of the triplicated...
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Báo cáo y học: " Genetic and functional analysis of HIV-1 Rev Responsive Element (RRE) sequences from North-India" pdf

... al.: Genetic and functional analysis of HIV-1 Rev Responsive Element (RRE) sequences from North-India. AIDSResearch and Therapy 2010 7:28.Submit your next manuscript to BioMed Central and take ... between HIV-1 subtypes B and C and with probably other subtypes as well. The analysis ofintra-subtypedivergence(geneticdistancefromIndian consensus sequence) and diversity (int ra-subtype genetic ... available on HIV-1 subtype C RRE genetic and functional character-istics. In the present study, we present in-depth genetic and functional analysis of RRE sequenc es from a cohort of 13 HIV-1 infected...
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Báo cáo y học: " Dimensionality and scale properties of the Edinburgh Depression Scale (EDS) in patients with type 2 diabetes mellitus: the DiaDDzoB study" pot

... 11:141http://www.biomedcentral.com/1471 -24 4X/11/141Page 7 of 19 RESEARCH ARTICLE Open Access Dimensionality and scale properties of the Edinburgh Depression Scale (EDS) in patients with type 2 diabetes mellitus: the DiaDDzoB ... here:http://www.biomedcentral.com/1471 -24 4X/11/141/prepubdoi:10.1186/1471 -24 4X-11-141Cite this article as: de Cock et al.: Dimensionality and scale properties of the Edinburgh Depression Scale (EDS) in patients with type 2 diabetes mellitus: ... Reprod Infant Psychol 20 05, 23 :143-154.35. Tuohy A, McVey C: Subscales measuring symptoms of non-specific depression, anhedonia, and anxiety in the Edinburgh Postnatal Depression Scale. Br J Clin...
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Báo cáo y học: " Diagnosis and phylogenetic analysis of Orf virus from goats in China: a case report" pot

... 10.1186/1743-422X-7-78Cite this article as: Zhang et al., Diagnosis and phylogenetic analysis of Orf virus from goats in China: a case report Virology Journal 2010, 7:78Received: 20 January 2010 Accepted: 25 April 2010 ... National Foot- and- Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Xujiaping No.1, Yanchangpu, Lanzhou, Gansu, 730046, ChinaReferences1. Hosamani ... editing and revision the manuscript.Author DetailsLanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National...
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Báo cáo y học: " Sequence and phylogenetic analysis of H7N3 avian influenza viruses isolated from poultry in Pakistan 1995-2004" pot

... Iqbal M, Yaqub T, Reddy K, McCauley JW: Novel genotypes of H9N2 influenza A viruses isolated from poultry in Pakistan containing NS genes similar to highly pathogenic H7N3 and H5N1 viruses. ... sequence from H7N3 AIV from Pakistan was included in the analysis. Results: Phylogenetic analysis revealed that there were two introductions of H7 into Pakistan and one N3 introduction. Only ... Table 1. Phylogenetic and Sequence Analysis Phylogenetic analysis included any available sequence data from H7N3 isolates from Pakistan (therefore differ-ent numbers of each gene were analyzed),...
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Báo cáo y học: " Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase" pot

... comprises the heart of the C-terminal domain is the only part of HIV-1 integrase yet to be visualized by structural biology. To ascertain the role of the tail region in integrase function and HIV-1 ... as the tail, were present in the two-domain HIV-1 construct,they were disordered and therefore unseen in the resultingcrystal structure [32]. The roles of the C-terminal tail in IN function and ... BioMed CentralPage 1 of 13(page number not for citation purposes)RetrovirologyOpen AccessResearch Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integraseMohd...
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Báo cáo y học: " Assessment and histological analysis of the IPRL technique for sequential in situ liver biopsy" ppsx

... Scott Lindsay from Veterinary PathologyDiagnostic Services, Faculty of Veterinary Science, University of Sydney, for assistance in interpretation of histology results. The authors acknowledge the ... obtaining two full and one partial lobe biopsies from the liver in situ during an IPRL exper iment. Our approach of retaining the liver in situ assists in minimising liver capsule damage, and consequent ... maintains the normal anatomical position of the liver during perfusion and it assists in keeping the liver warm and moist. Maintaining the normalFigure 2 Sequential lobe biopsy during IPRL (part...
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Báo cáo y học: "Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia" pps

... AccessResearchReconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxiaTunahan ầakr1, Selma Alsan1, Hale Saybasál2, Ata Akn2 and Kutlu ... uptake and degradation of glycine by astroglial cells inculture: synthesis and release of serine and lactate. Glia 1999,27:239-248.55. Yamasaki M, Yamada K, Furuya S, Mitoma J, Hirabayashi Y, ... due to a high rate of glycolysis to mitochondria. Following thislogic, the glycerol-3-phosphate shuttle was proposed to beactive in astrocytes [31], which is validated by the pres-ence of cytosolic...
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Báo cáo y học: "Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning" ppt

... the skin and Analysis of neural crest stem cell associated transcripts in BMP2+ cellsFigure 3 Analysis of neural crest stem cell associated transcripts in BMP2+ cells. (a) RT-PCR analysis for ... MXD and JH designed the study. MXD and RHA per-formed the experiments. SB, MO and CW did immunohisto-chemical analysis. SC, JW, HS, IS, OH and NH did theAffymetrix analysis. MXD, JW, SC and ... Detection of p75 and GFAP in BMP2+ cells labelled by immunohistochemistry. Immunuostainings with anti-p75 (left panel) and anti-GFAP (right panel) to show the presence of NCSCs and the astrocytes,...
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Báo cáo y học: "Sequence and structural analysis of BTB domain proteins" pps

... vertebrate BTB- ZF and BBK proteins are more closelyrelated, and cannot be separated by BLASTCLUST.Long form of the BTB domain The majority of BTB domains from the BTB- ZF, BBK, MATH- BTB, RhoBTB and BTB- basic ... DPEVFRCVLNFYRTGKLHYPYEC SAYDDELAFYGI LPEI I GCCYEEYFFDR NRPSFDAILYFYQSGGRLRR PVNVPLDVFSEEI KFYELGGRI ELK. QFDSHI LEKAVEYLNYNLKYSGVSEDDDEI P EFEIP.TEMSLELLLAADYLSINEVNFRE. I PSHVLSKVCMYFTYKVRYTN. . ... sequenced eukaryotes. The BTB domain is typically found as asingle copy in proteins that contain only one or two other types of domain, and this defines the BTB- zinc finger (BTB- ZF), BTB- BACK-kelch...
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Báo cáo y học: "Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins" doc

... IFIFLYLYP Y E L Y G LDPDPRPLPLD K F F LYLYP Y E L Y G LDPDPRPLPLD F IFIFLYLYP L Y G LDPDPRPLPLD K F IFIFLYLYP Y E L Y G LDPDPRPLPLD K F IFIFLYLYP Y E L Y G ... LFYNVTYT A YRLS FGF EYSNL TEIG KKLT RF RY G TDRT GYFTN STRFLLHKQWT L YSLT YKF SYSN- KEYSR L NA FIVAE KQ K LAVE VLLHKQWT I YSLT YKF SYSN- KDYSR L SA FIVAE KQ K VAVE VLLSKQWT L YSVT MH KF SYTN- ... F I Y P E L Y G LDPDPRPLPLD K F IFIFLYLYP Y E L Y G LDPDPRPLPLD K F IFIFLYLYP Y E L Y G LDPDPRPLPLD K F IFIF Y P Y E L Y G LK L Y mgNdc80ncNdc80spNdc80scNdc80caNdc80drNdc80hsNdc80mmNdc80xlNdc80FungiMetazoaatNdc80Plantae75%75%PCNA...
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Báo cáo y học: "A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection" doc

... for Q RT-PCRPrimer Alias Sequence1082 ACT1F GCCTTCTACGTTTCCATCCA1083 ACT1R GGCCAAATCGATTCTCAAAA1367 PAC2F AATAACGAATTGAGCTATGACACCAA1368 PAC2R AGCTTACTCATATCGATTTCATACGACTT1172 BUD6F CAGACCGAACTCGGTGATTT1173 ... validate the microarray data, we used quantitativeRT-PCR to examine the expression of five of the up-regulatedgenes in a set of RNA samples that had been used in the array analysis (Figure 3a) . ... GOstats analysis of genes altered in CDC13+ strains. Table D shows GOstats analysis of genes altered in cdc13-1 strains that are not cell cycle regulated. Tables E-Q show GOstats analysis of genes...
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