DNA Methylation: Basic Mechanisms - Part 7 docx

... 1 , 2 875 9 Bremen, German y a. j eltsch@iu-bremen.de 1In t r oduct i o n 2 04 2Cata l ytic Mec h anism o f DNA- (Cytosine-C5)-MTases . 20 6 2.1 Reaction Mec h anism o f DNA- (Cytosine-C5)-MTases ... Aci d s Res 29: 378 4– 379 5 Ch uang LS, Ian HI, Ko h TW, Ng HH, Xu G, Li BF (19 97) Human DNA- (cytosine-5 ) met h y l trans f erase-PCNAcomp l ex asa target f or p21WAF1. Science 277 :19...

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DNA Methylation: Basic Mechanisms - Part 1 pptx

... novel approaches of how to proceed further. Repetitive DNA sequences, particularl y retrotransposon-derived DNA or endo g enous retro- vira l sequences, are in genera lh eavi l y met h y l ate d . ... Res 22:2990–29 97 Constantinides PG, J ones PA, Gevers W ( 1 977 ) Functional striated muscle cells fro m non-myo bl ast precursors f o ll owing 5-azacyti d ine treatment. Nature 2 67: 3...

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DNA Methylation: Basic Mechanisms - Part 2 ppsx

... an d h ippocampa lf unction. Proc Nat l Aca d Sci U S A 100: 677 7– 678 2 DNA Meth y ltransferases: Facts, Clues, M y sterie s 5 9 4 . 2 T arget i ng of DNMTS by DNA- Bound Transcr i pt i on Factors A nother possible ... interacting d omain; C XX C ,Cys-ric hd omain ; ( E ) 1 2 , G l u repea t; ( GR ) 11 , G l y-Arg repeat; MBD , met h y l -CpG- b in d ing d omain ; Hh H-GPD,DN A N-Gl y c...

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DNA Methylation: Basic Mechanisms - Part 3 pptx

... new f ami ly o f DNA- b in d in gf o ld s. Na t Struc t Bio l 9:2 17 22 4 Razin A, Ce d ar H (1 977 ) Distri b ution o f 5-met h y l cytosine in c h romatin. Proc Nat l Aca d Sci U S A 74 : 272 5– 272 8 90 B. ... (Organe ll e) Speci ﬁ city 7 1 2.2.5 Intragenome Speci ﬁ city 7 2 2.3 Rep l icative DNA Met h y l ation an d Demet h y l ation 74 2.4 C y tosine DNA Meth y ltransferases...

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DNA Methylation: Basic Mechanisms - Part 4 ppsx

... Bio l C h em 277 : 377 41– 377 4 6 Stokes T (2003) DNA- RNA-prot ein g an g to g ether in silence. Trends Plant Sci 8:53–5 5 Sturaro M, Viotti A (2001) Meth y lation of the Opaque2 box in zein g enes is parent- d epen d ent ... meth y ltransferases in RNA-directed DNA meth y lation. C urr Biol 13:2212–221 7 Casti lh oA,NevesN,Ru ﬁ ni-Castig l ione M, Viegas W, Hes l op-Harrison JS (19...

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DNA Methylation: Basic Mechanisms - Part 5 pot

... non-5  -CG -3  C-residues were never meth y lated. Around exon 1 of the S NRPN g ene, more t h an 96% o f t h e23 5  - CG - 3  - d inuc l eoti d es were met h y l ate d on t h emater - na l c h romosome, ... Pol y merase I-Transcr i bed Human R i bosomal Gene s Th e5  - CG - 3  -rich promoter re g ion of the DNA- dependent RNA pol y merase I (rDNA) g enes wa...

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DNA Methylation: Basic Mechanisms - Part 6 pps

... Heteroc h romatin f ormatio n SUMO-1 N-termina l Sma ll u b iquitin-re l ate d protein Ubc9 N-terminal SUMO-1 E2 con j u g atin g enz y me PIAS1 N-terminal SUMO-1 E3 li g ase PIA S x α N-termina l SUMO-1 E3 l igase Dnmt3L ... RA R β . PML-RAR-induced re p ression of RAR β t ranscription was partia ll yre l ease db y 5-aza- d C, in d icating t h at DNA met h y - lation contributes to the...

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DNA Methylation: Basic Mechanisms - Part 8 pdf

... si l encing b yen d ogenous DNA met h y l ation . Proc Nat l Aca d Sci USA 95: 872 7– 873 2 Hollida y R, Pu g h JE (1 975 ) DNA modiﬁcation mechanisms and g ene activit y durin g develo p ment. Science 1 87: 226–232 Ja bl on k aE,Lam b MJ ... 24:20 9 –218 E l-Maarri O (2004) SIRPH anal y sis: SNuPE with IP-RP-HPLCfor quantitativemeasure- ments of DNA meth y lation at speciﬁc CpG site...

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DNA Methylation: Basic Mechanisms - Part 9 pps

... (1991) The vsr g ene product of E. coli K-12 is a stran d -an d sequence-speci ﬁ c DNA mismatc h en d onuc l ease. Natur e 3 53 :77 6 77 8 Hernan d ez-Boussar d TM, Hainaut P (1998) A speci ﬁ c ... Mutat Res 477 :7 2 1 Johnson RE, Yu SL, Prakash S, Prakash L (2003) Yeast DNA pol y merase zeta (zeta) is essential for error-free replication past th y mine g l y col. Genes Dev 17: 77 8 7...

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DNA Methylation: Basic Mechanisms - Part 10 pot

... prote i n8 5 A TRX- h omo l ogy d omain 1 87, 19 2–1 94 a ut i sm 36 au xin 75 5-aza- 2  deox y c y tidine 18 7 5-aza-d C 18 7 5-azac y tidine 73 , 19 1 base ﬂippin g 208–210 b enzo [ a ] pyrene 271 BER-coupled remeth y lation ... Clonin g and expressionof human G/T mismatch-speciﬁc th y mine- DNA glycosylase. J Biol Chem 271 :1 276 7–1 277 4 C y tosine Meth y lation and DNA Rep...

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