... markedly
increased ERK1 and ERK2 expression and attenuated
reperfusion lung injury and apoptosis, thus presenting a
promising approach for moderating lung injury and
supporting recovery after clinical ... the c-Jun amino-terminal protein kinases
(JNKs), and p38 kinases. Notably, whereas ERK1 and ERK2
exert a cytoprotective effect and are involved in cell
proliferation, transfo...
... colleagues evaluated in vivo and ex vivo regulation
and expression of human β-defensin 2 (hBD2) in 16 septic
Review
Year in review 2007:
Critical Care
– multiple organ failure and
sepsis
James M ... group-box protein 1, lipopolysaccharide-binding
protein and procalcitonin levels were higher in patients than
in healthy control individuals. None of the biomarke...
... 12
hours after initiating treatment (p <0.05). Other infusions
Review
Year in review 2006:
Critical Care
– paediatrics
Carolina F Amoretti
1
and Robert C Tasker
2
1
Paediatric Intensive Care Unit, ... acute renal injury and were
receiving norepinephrine/epinephrine (NE/E) and hydrocorti-
sone. The three patients with septic shock showed improve-
ment in blood pres...
... apoptosis in the lung and other organs, including
the liver and the diaphragm. The clinical importance of these
findings is not clear, and further study is needed to see
whether these findings are ... the
integration of this technique with a strategy to open the lung
and maintain adequate end-expiratory lung volume. We
review two papers from the group in Mainz, reporting studies...
... cardiological section of Critical Care. It
also confirms the wide ranging research interests of the
intensive care community. We hope that these interests will
continue and expand.
Competing interests
The ... undergoing oesophagectomy were
randomly assigned, in a double-blinded fashion, to receive
intravenous nitroglycerin or saline during gastric tube
construction, and microvascul...
... fluid balance in septic patients.
Experimental data from Dubin and colleagues in Argentina
bring us interesting data regarding increasing oxygen delivery
through fluid resuscitation in a septic ... sepsis,
and a lower bacterial load was observed in the treatment
group. This intriguing finding must be demonstrated in other
settings, but this could be a future approach to settin...
... Gainnier M, Sainty JM, Auffray JP, Papazian L:
Influence of support on intra-abdominal pressure, hepatic
kinetics of indocyanine green and extravascular lung water
during prone positioning in ... sedation, and prone positioning); infection
(pneumonia and sepsis); monitoring (ventilatory monitoring,
pulmonary artery catheter and pulse oxymeter); and education
(training and health...
... prevention; physiology; and procedures and techniques.
Introduction
This review article summarizes original research papers in
cardiology and critical care published in 2005 in Critical Care.
The papers ... quality. In the review by
Poeze and coworkers [17] 30 RCTs were scored for quality
from 0 to 16 (incorporating randomization, blinding, selection
and interven...
... higher in these
latter patients both at baseline and after gastric feeding.
Furthermore, while fasting and postprandial cholecystokinin
and peptide YY plasma levels and gastric emptying were
inversely ... the
macrocirculation and microcirculation during shock, focusing on
arginine vasopressin, erythropoietin and nitric oxide; studies on
metabolic homeostasis (acid–base status, e...
... years in critical
care [20-23] for benchmarking, process improvement and
standardizing illness severity in clinical studies. An interesting
report by Hofhuis and colleagues [24] explored the influence
of ... There is a growing need for further research
specifically examining relationships between staffing models
and outcomes.
Review
Year in review 2007:
Critical Care
-...