... regarding PTPN22 +1858C/
T polymorphism and PsA have produced conflicting
results. In a study by Hinks et al., no association was
found between PsA and PTPN22 +185 8C/T in a patient
population from the ... regression analysis (P = 0.017). There was no
association between dactylitis and deformed joints and,
no other significant associations between the ca rriage of
th...
... of the study and to the interpretation of the
results. LP had the main responsibility for the genetic analyses
and contributed to the analysis and interpretation of the
results. LA and LK were ... of the manuscript. CB contributed to
the design of the study, to the collection of the data, to statis-
tical analysis and to the writing of the manuscript. IL...
... allele to
the risk for development of the disease is unknown and prob-
ably modest. The problem is further complicated by the fact
that many of these alleles interact with other genes in the back-
ground ... case-control
study conducted in the Swedish population [17] failed to rep-
licate the association between RA and the TNFRII 196M/R
polymorphism. That study revealed...
... investigated
the relationship between the VDR polymorphisms and
diseases. The effect of VDR polymorphisms in renal
failure has been explored, and Sezer et al.
demonstrated that the BsmI polymorphism ... an association between
bone mass and polymorphisms of the recognition sites
of the restriction enzymes BsmI and ApaI in the 3'-end
of the VDR gene, an...
... transmembrane glycoprotein that is mainly
expressed by T-lymphocytes, monocytes/macrophages
and dendritic cells. The CD4 receptor normally functions
as a coligand and coreceptor of the major histocompati-
bility ... [3-5].
The equilibrium established between these different
forms may vary according to the cell type, the activation
state of the cell and the redox conditio...
... to
determine the association between the circulating
sCD40L levels and m ortality, and the secondary objec-
tive to determine the association between circulating
sCD40L, inflammatory and prothrombotic ... its
association with sCD40L levels. There are been reported
an association between sCD40L levels and severity of
acute coronary artery syndrome [31] and between tro...
... parameters and the
presence and severity of meniscal tears. The potential effect of
Table 3
Association between foot rotation during early and late stance and the presence and severity of meniscal ... morphology and the genesis of knee OA and
pain [8-11]. The peak external knee adduction moment, which
is generated by the combination of the ground reaction force
p...
... days; record two—100 mg/30 days, 200
mg/30 days), we summed the daily dose and divided by the number of records
and summed the days-supply (e.g. 300 mg/60 days).
Using these decision rules, we ... days, daily dose was
summed to the maximum days-supply between the 2 prescriptions.
b. If the days-supply between prescriptions was greater than 14 days, dose was
considered...
... with the more frequent -28C, suggesting
that the polymorphism can increase RANTES expres-
sion in the human body [12]. Therefore, it’s reason-
able to hypothesize that the RANTES -28C/G poly-
morphism ... asthma severity [29].
Therefore, as one of the C-C chemokines, the
RANTES polymorphisms necessarily resulted into the
level of eosinophils elevating correspond, and the...