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Báo cáo y học: " Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro" ppsx

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Báo cáo y học: "Communication between secondary and primary care following self-harm: are National Institute of Clinical Excellence (NICE) guidelines being met" ppsx

... Content of communications from secondary services to primary care services according to recommendations by Royal College of Psychiatrists (2004)Type of information Any communication, including ... National Institute for Clinical Excellence: Self-harm: the short-term phys-ical and psychological management and secondary prevention of self-harm in primary and secondary care. Clinical guideline ... Institute of Clinical Excellence (NICE) guidelines being met?Jayne Cooper*1, Elizabeth Murphy1, Rita Jordan2 and Kevin Mackway-Jones3Address: 1Community Based Medicine, Department of Psychiatry,...
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Báo cáo y học: "Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families" pot

... Tables of indels and SNPs in four or moreprobands in our population. (a) Table of indels appearing in four ormore probands in our population (n = 11). (b) Table of SNPs in four ormore probands in ... damaging by Polyphen2 and SIFT (Tables 2 and 3).WFS1Family K13576 is of Ashkenazi Jewish origin. Hearingloss in the family is dominant (Figure 2). Audiograms of affected relatives reveal hearing ... novelvariants in MYO15A (Tables 2 and 3). The first variant,corresponding to MYO15A c.8183G > A (p.R2728H),was supported by 50% (43/86) of reads and is predictedto be damaging by PolyPhen2 and SIFT....
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Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"

... Lacey D, Hill D, Chen Y, Fletcher F, Hawley RG, McNiece IK A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone ... R, Takayama T, Kato J, Yamauchi N, Ko-gawa K, Sakamaki S, Hirayama Y, Kohda K, Niitsu Y. Involve-ment of transforming growth factor-beta and thrombopoietin in the pathogenesis of myelodysplastic ... Giraudier S, Vainchenker W, Wendling F. Prominent role of TGF-beta 1 in thrombopoi-etin-induced myelofibrosis in mice. Blood 2002;100:3495-503 32. Erusalimsky JD, Franklin R and Hong Y. Is the...
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Báo cáo Y học: SF2/ASF protein inhibits camptothecin-induced DNA cleavage by human topoisomerase I potx

Báo cáo Y học: SF2/ASF protein inhibits camptothecin-induced DNA cleavage by human topoisomerase I potx

... &Tazi, J. (1998) Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrates determines phosphorylation of SF2/ASF splicingfactor. Nucleic ... 3. Binding of htopo I and SF2/ASF to DNA revealed by mobilityshift assay. (A) Binding of htopo I to DNA. Lanes: 1, DNA alone;2, DNA + 0.14 pmol htopo I. (B) Aggregation of DNA by htopo I and ... phos-phorylated in the preparation used in the cleavage assay asÔphosphorylated SF2/ASFÕ.The amount of htopo I and SF2/ASF was quantified by densitometric scanning of SDS-polyacrylamide gels usingBSA...
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Báo cáo y học: "Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized" ppsx

... radiographic evidence of knee OA.Urinary excretion of pyridinium cross-links is significantlyincreased in patients with large joint OA and hand OA, sug-gesting an increased rate of bone turnover ... resorption plays an integral role in the diseaseprocess, with increased levels of bone resorption markers,including type I collagen [18] and deoxypryidinoline [19],reported in patients with radiographic ... 800mg hydroxyapatite/cm) provided by the system manufacturer.The tissue mineral density was calculated only for voxelsexceeding the threshold (that is, only for voxels occupied by mineralized...
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Báo cáo y học: " Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores" pptx

... limited by size, and by examining onlyone trial. Validation would require calculations to be performedon a larger set of trials using individual patient data not availa-ble in publications, and ... analgesics. Pain 2006, 121:1-5.11. Moore RA, Edwards JE, McQuay HJ: Acute pain: individualpatient meta-analysis shows the impact of different ways of analysing and presenting results. Pain 2005, ... better indication of efficacy in osteoarthritis trials than mean pain scoresR Andrew Moore1, Owen A Moore2, Sheena Derry1 and Henry J McQuay11Pain Research and Nuffield Department of Anaesthetics,...
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Báo cáo y học: " High blood pressure, antihypertensive medication and lung function in a general adult population"

... Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC: Lung volumes and forced ventilatory flows. Report Working PartyStandardization of Lung Function Tests, European Community for Steel and ... Education, Science, Research and Technology and by the State of Bavaria.The work was supported by the Competence Network Asthma/COPD funded by the Federal Ministry of Education and Research (FKZ 01GI0881-0888).Author ... Valind S, Hedblad B, Janzon L: Blood pressure increase between 55 and 68 years of age is inversely related to lung function: longitudinal results from the cohort study ‘Men born in 1914’.J Hypertens...
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Báo cáo y học: "Discriminating between elderly and young using a fractal dimension analysis of centre of pressure"

... easily presented and provides a simpler means by which to quantify a non-linear system and as such may be more readily accepted by clinicians. The potential of the fractal dimension analysis is yet ... characterised by constraining the degrees of freedom to control the system, and subsequent releasing of these degrees of freedom allowing for greater adaptability to their environment. These findings ... person’s COP remains within allowable limits, the person will remain standing upright. Difficulty lies in deciphering the information contained within these traces and distinguishing one from...
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Báo cáo y học: "Anti-Sa antibodies and antibodies against cyclic citrullinated peptide are not equivalent as predictors of severe outcomes in patients with recent-onset polyarthritis" pdf

... resulting from thedeimination of peptidylarginine to peptidylcitrulline residueshave been described in the serum of patients with RA [19].These include antibodies targeting cyclic citrullinated ... chronic inflammatory arthritisthat frequently starts at the peak of productive life and is amajor cause of invalidity, morbidity, and premature mortality[1]. RA is characterized by an early inflammatory ... Barrett E, Silman A, Symmons D: Disability in patients with early inflammatory polyarthritis cannot be'tracked' from year to year: an examination of the hypothesisunderlying percentile reference...
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Báo cáo y học: "Sternum wound contraction and distension during negative pressure wound therapy when using a rigid disc to prevent heart and lung rupture" pps

... wound contraction and distensionduring negative pressure wound therapywhen using a rigid disc to prevent heart and lung ruptureSandra Lindstedt1*, Richard Ingemansson1 and Malin Malmsjö2AbstractBackground: ... rupture, lung rupture,bypass graft bleeding and death; the incidence being 4to 7% of all patients treated for poststernotomy medias-tinitis with NPWT after cardiac surgery [2-4]. In November ... anterior part of the heart and theinside of the thoracic wall [10]. Heart and lung ruptures* Correspondence: sandra.lindstedt@skane.se1Department of Cardiothoracic Surgery, Lund University and Skåne...
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