Báo cáo y học: "Impaired expression of mitochondrial and adipogenic genes in adipose tissue from a patient with acquired partial lipodystrophy (Barraquer-Simons syndrome): a case report" pot
... is a case report of a 44-year-old woman with acquired partial
lipodystrophy. To obtain insight into the molecular basis of lipoatrophy in acquired partial
lipodystrophy, we examined gene expression ... expression in adipose tissue from this patient newly diagnosed
with acquired partial lipodystrophy. A biopsy of subcutaneous adipose tissue...
... 5¢-TGCAGAGTTCcAtATGGTTGATCAAG-3¢
Antisense 5¢-CGAAAAAAGGAGGAAGAAGCAATGC-3¢
aac2 (A. t.) Sense 5¢-TGTAGAGGTTcAtATGGTTGAACAGACTC-3¢
Antisense 5¢-CTTAATGACTGCGGGATTTGGTGGTAC-3¢
aac3 (A. t.) Sense 5¢-CTGATTTGTACAAcAtATGGATGGATC-3¢
Antisense ... calculated
apparent molecular masses (Fig. 1, lanes 2–8). Notably,
the expression levels of AAC2 from rat, AAC1 from
potato and AAC3 from Arab...
... compared with B cells
from healthy individuals and also from patients with OA. In
patients with RA and patients with SLE a fraction of B cells
showed decreased expression of CXCR5, CXCR4 and
CCR6, ... negligible. A comparable result was found
with blood samples from patients with OA and also with most
patients with SLE. In contrast, in patients w...
... the
colocalization and activation of FAK, Pyk2, Src and paxillin in
RA and OA patient& apos;s ST lining and sublining may be important
for integrin-mediated signaling.
pPLCγ expression pattern
Upon ... pFAK reactivity in normal ST lining (arrow) and subsynovial macrophages (arrowhead). (d) The quantification of data obtained from
a, b and c. Bars represent the mean...
... of circadian clock gene, mPer1, in mouse brain
and kidney under morphine dependence and withdrawal
Xiaojia Wang
1,2
, Yueqi Wang
1,2,4
, Haoyang Xin
3
, Yanyou Liu
1,2
,
Yuhui Wang
1,2
, Hang ... organs.
Introduction
Circadian rhythms are about-daily variations of physio-
logical functions that are found in every living organism
on earth ranging from bacteria to mammals. These...
... our system. We also
compared data obtained with our system and data obtained with an Actiwatch device. Finally, to
validate the system, results obtained from the automated observation of 6 rats ... overcome by including a segmentation step or, for
a small number of animals, by launching as many proc-
esses as different animals/cameras in the experiment.
Observation and spe...
... aminobutyrate-pyruvate, b-alanine-pyruvate and
dimethylarginine-pyruvate aminotransferase activities.
In the rat, gluconeogenesis from l-serine takes place
mainly through l-serine dehydratase, whereas the flux
through ... present
in knockout mice. Acads, acyl-coenzyme A
dehydrogenase, short chain; Aco1,
aconitase 1; Agt
)
, alanine-glyoxylate
aminotransferase knockout; Aldh2, aldehyd...
... for
each patient at baseline and at three, five and 10 years: sex,
age, disease duration (at baseline), pain on a visual analog
scale (VAS), duration of morning stiffness, number of tender
and ... discordant in part, so the
association between damage and disability remains uncertain.
Several assessment tools are available for measuring func-
tional capacity. The easiest and...
... autoantibodies
(for example, anti-U1-RNP or anti-PMScl).
Data recording and statistical analyses
The DNSS maintains a centralized online patient registry in
which all patient data from the four-page DNSS -patient ... arthritis.
Multivariate analysis accounting for these factors, however,
failed to demonstrate a significantly increased use in these
patients.
Azathioprine, orig...