... Experimental infection with GX0101 Meq showed that deletion of the Meq
gene significantly decreased immunosuppression in chickens caused by pathogenic MDV.
Conclusion: These findings suggested that the Meq ... 8:2
http://www.virologyj.com/content/8/1/2
Page 2 of 8
RESEARCH Open Access
Deletion of the meq gene significantly decreases
immunosuppress...
... decrease in the activity
for the 11b-hydroxylase, CYP11B1. Intriguingly, however,
the 11b-hydroxylase activity of the aldosterone synthase
CYP11B2 was basically unaffected whereas the 18-hydroxy-
lation ... the proteins of the CYP11B
subfamily catalysing the last biosynthetic steps are the key
enzymes for the synthesis of both mineralocorticoids and
glucocorticoids...
... were followed in order to determine the degree
of uncoupling of the enzyme. The term ÔuncouplingÕ
describes the observation that the electrons derived from
the oxidation of NADH by the Na
+
-NQR ... already inactivated in the membrane-
bound state if the cells are disrupted in the presence of
dioxygen, resulting in an uncoupling of NADH oxidation
and Q...
... oscillator
composed of machinery involved in the synthesis of
trehalose [26]. We hypothesized that the synthesis of
trehalose parallels activation of the glycolytic pathway,
and trehalose is degraded by trehalase ... site of GTS1 (B) in the two-hybrid system. Binding
activity was determined by measuring b-galactosidase activity in
colony lifts and in liquid cultu...
... controls were included across the plates to
ensure accuracy of genotyping. In addition, for all the assays,
genotyping was confirmed in a subset of samples using the
Pyrosequencing genotyping method ... randomly
distributed across the United Kingdom. Genotype data gener-
ated from the 64 non-White individuals included in the cohort
was not included in the analysis....
... Edition.
Consent
Written informed consent was obtained from the patient
for publication of this case report and any accompanying
images. A copy of the written consent is available for
review by the Editor -in- Chief of ... of the cervical spine 20 years after radiotherapy treatment for a T1aN0M0
laryngeal carcinoma resulting in quadriplegia.
Conclusions: Radiotherapy carri...
... Doses
of 150 μg or higher provide sustained bronchodilation
that is largely independent of disease severity.
Finally, it is instructive to place the findings of this
analysis in the context of the ... marker of disease severity, was the key covariate. The
impact of baseline FEV
1
onthedoseresponseinthe
absence o f any model-based interpretation is shown in
figure...
... chromosomes induce
cortical actin and myosin II assembly into a distinct
actincapsurroundedbyamyosinIIringintheMII
eggs [6]. Interestingly, sperm chromatin incorporation at
fertilization or m icroinjection ... likely by activating myosin II
contractility [16]. Consistently, inhibition of myosin II
contraction by using bl ebbistatin [17] or myo sin light
chain kinase by ML-7 [18] all b...
... percentage of codons ending in C or G, when com-
pared to both the entire set of 78 orthologous OXPHOS genes
and the gene subset including only their parent genes. In
samples including all the OXPHOS gene ... based on
a single regulatory element, coordinates the expression of the
whole set of energy-producing genes in Drosophila [57].
The comparative analysis of...
... decrease
in protein synthesis that is at least as marked as that provoked
by H
2
O
2
. Therefore, the ability to respond by decreasing the
rate of protein synthesis is not the only factor determining
resistance ... out by pooling the
entire collection of mutants and growing them in competition
under the condition of interest [11,15]. Analysis of the compe-
tition...