... effects on the levels of glutathione and the
activities of the antioxidant enzymes. Finally, the corre-
lations existing between the antioxidant systems and the
SAPS and SANS scores in our patients ... of decreased plasma levels of GSHt and GSHr, and impaired antioxidant enzyme
activities in drug-naive first-episode patients with schizophrenia. The GSH...
... protein domains.
Human C4bp has been shown to bind other compounds
including protein S (β chain), C-reactive protein, serum amy-
loid protein, soluble CD40 ligand, CD40 (α chain), heparin (α
chain), ... activation by C-reactive protein: targeting
of the inhibitory activity of C4b-binding protein. J Immunol
2006, 176:7612-7620.
22. Webb JH, Blom AM, Dahlback B: The binding of protein S and
t...
... Germany.
21
Department of Psychiatry
and Psychotherapy, Hospital Ingolstadt, Germany.
22
Department of Psychiatry
and Psychotherapy, Hospital Lübbecke, Germany.
23
Hospital of Psychiatry
and Psychotherapy, ... Psychiatry and Psychotherapy Merxhausen, Kassel,
Germany.
11
Department of Psychiatry and Psychotherapy, University of
Rostock, Germany.
12
Hospital of Forensic Psychiatry, Mo...
... immunoregulatory and proinflammatory cytokine, has
been shown to play an important pathogenic role in Th1-driven
autoimmune disorders. In this study, we evaluated the
circulating levels and salivary-gland ... lymphocytic infiltration in sali-
vary gland, a finding that indirectly suggests that the
increase in lymphocytic infiltration is accompanied by the
up-regulation of Th1 cy...
... CD8
+
lym-
phocytes were gated for analysis based on light scattering
properties and on CD4 or CD8 and CD45 staining. Data
were collected for 10
4
lymphocytes. Positively and nega-
tively stained ... Th1-type and Th2-type cytokine and chemokine
receptors has been described. Thus, the local cytokine
milieu might depend on the site and extent of disease
activity [4,5]. The shift in...
... Germany). Hypergammaglobulinemia was
diagnosed if γ-globulin levels were above 19% in the protein
electrophoresis.
HLA-DR typing
Generic HLA-DR typing was performed by using an enzyme-
linked ... broad-spectrum
proinflammatory cytokine with a pivotal role in the regulation of
innate and adaptive immune responses [5]. There is increasing
evidence for a role of MIF as a proinflammator...
... glycoxidation product N(epsilon)-(carboxymethyl)lysine
in human tissues in diabetes and aging. J Clin Invest 1997,
99:457-468.
37. Le Maitre CL, Freemont AJ, Hoyland JA: The role of interleukin-1
in ... Hoyland JA, Freemont AJ: Interleukin-1 receptor
antagonist delivered directly and by gene therapy inhibits
matrix degradation in the intact degenerate human interverte-
bral disc:...
... for extracting homozygous segments from high-density
genotyping datasets, quantifying their local genomic structure , identifying outstanding regions within the genome
and visualizing results ... heterozygosity thresholds, SNP density).
In examining and quantifying contiguous homozygos-
ity, chromosome X stood out as possessing much longer
homozygous segments compared to similarly sized...
... an intriguing effect in SDF-1 expression neutralizing
the significant decrease in its expression observed in
untreated hypertriglyceridemics (U-Mann-Whitney, p =
0.026; Figure 1B), presumably increasing ... Stanley T, Wilson PW, D'Agostino RB, Grinspoon S:
Metabolic abnormalities and cardiovascular disease risk fac-
tors in adults with human immunodeficiency virus infection
an...
... Nabiryo C,
Coutinho A: Use of WHO clinical stage for assessing patient eligibility to
antiretroviral therapy in a routine health service setting in Jinja, Uganda.
AIDS Research and Therapy 2008, ... stigmatization
and discrimination a gainst HIV infected persons in the
community despite all the many years of awareness and
the availability of life saving treatment. Additionally, th...