báo cáo khoa học: " Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor d from Peroxisome proliferatoractivated receptor g in the ob/ob mouse" ppt
... skeletal
muscle the concentrations of adenine were decreased and
those of adenosines and ribose sugars from the adenosines
were increased. Therefore, the decrease in amino acids may
relate to increased oxidative ...
((dd))
Bar graph demonstrating the difference in the average integrated area of the serine
peak from control and PPARd agonist treated liver. Error...
... Scores and X-loading Weights and Y-loa-
dings in PLS regression shown in Fig. 5.
Figure S4. Residual variance of calibrated X and of
validated Y (NADPH) in PLS regression shown in
Fig. 5.
Figure ... the genes gndA, gsdA and tktA
To be able to manipulate the genes gndA, gsdA and
tktA encoding 6PGDH, G6 PDH and TKT, respect-
ively, these genes were cloned by screening an A. nig...
... considered to be inappropriate, since TAE may cause
hepatic infarction because of an a lready occluded portal
vein. Under US and digital subtraction angiography
(DSA) guidance (Figure 1b), the ... contributions
HT reviewed relevant literature and drafted the manuscript. All authors
provided clinical expertise and participated in drafting the manuscript. And
all authors read and ap...
... for death increased with
the NRBC concentration and seems to decline again when the
NRBCs have disappeared from the circulation. The prognostic
significance of NRBCs was independent of other ... concentration of
NRBCs in the blood, but the prognosis improved when the
NRBC concentration decreased. In particular, after the first
detection of NRBCs in blood and...
... that invertase activity is increased during cold
exposure in Rsch, whereas acitivity is reduced in C24
after 7 days in the cold. Regarding the question of
Systems biology of cold acclimation in ... showed significantly higher
activities of vInv at 0, 1 and 3 days of cold exposure.
The activity of vInv in Rsch increased continuously
during cold exposure, and became...
... and play a role in
Tourette’s syndrome, nicotine addiction and Parkinson’s
disease. Thus, nAChRs modulating the dopamine release
gain increasing interest as drug targets, and identification of
the ... subunits).
c
Unless
otherwise indicated, K
i
values for inhibition of epibatidine binding are shown; B, inhibition of a-BTX binding.
d
Indicates cases where K
d
values were obtain...
... conforma-
tional integrity. During protein unfolding ⁄ refolding,
the addition of 2.5 protons (both E75 and E129 are
the targets of protonation) results in SNase unfolding,
with refolding at an early stage ... refolding
[21]. Since then, many scientists have been interested in
demonstrating this concept by using N-terminal and
C-terminal fragments of SNase as models for the st...
... for
the protein undergoing either aggregation or native
folding.
Analysis of the modulation of aggregation in bacte-
ria was also of support in clarifying critical steps of
oxidative folding of ... on
formed aggregates triggering the degradation of mis-
folded proteins while ClpB releases them from inclu-
sion bodies (IBs) and presents unfolded polypeptides
to the...
... tissue retains the ability
to generate new adipocytes throughout life. Increased
adipocyte number during aging has been implicated in
the rising incidence and severity of obesity among the
elderly ... of increased prolifera-
tion or recruitment of preadipocytes [12], suggesting
that these cyclin-dependent kinase inhibitors are
important in the regulation of adipocyte n...
... 5¢-CCC TGA
AGC CAG GAT GAG CCG CAG GGA AAG-3¢ and
5¢-TGG AGC TC G CTG ATT GGC CAG AAG CTG CAA-
3¢) was used for the following EMSA assay. The DNAÆpro-
tein binding reaction was conducted in a mixture ... 5¢-TCT TGG ACA
CGG TAG CAG AG-3¢; Ppp2r5c, forward, 5¢-AGT ACC
TGG GGA TTG GC-3¢; Ppp2r5c, reverse, 5¢-CAT GGC
TTG ATA TAC AAC GC-3¢; Gapdh, forward, 5¢-GGG
CAC TTA CGG GTG TTA GA-3¢;...