Báo cáo y học: "A dynamic model of gene expression in monocytes reveals differences in immediate/early response genes between adult and neonatal cells" potx
... of differences in gene expression of adult and cord blood monocytes in response to LPSFigure 2
Heat map representation of differences in gene expression of adult and cord blood monocytes in response ... Access
Research
A dynamic model of gene expression in monocytes reveals
differences in immediate/early response genes bet...
... thin and bold lines,
respectively). We used a threshold to limit the analysis to the
800 strongest regulating genes (genes with significantly
changing expression levels). Inclusion of more genes ... down-regulated genes of each of the investigated strains,
HB3, 3D7, and Dd2. Due to an overlap between these data-
sets, the analysis resulted in a list including a total o...
... morphology assays,
respectively. Since cytosine-arabinoside alone induced an
apoptosis of 15%, we have that f
s
(PreImatinib but in the
presence of cytosine-arabiniside) was0.85. Substituting
this into ... tyrosine kinase inhibitor that specifically
binds the ATP pocket of Bcr-Abl tyrosine kinase, inhibit-
ing the activity of the kinase. Moreover, it is known to
induce apoptosis in...
... (wingless int) signaling by stabilizing
β-catenin, we investigated the expression of Wnt genes in
treated embryos. A Q-PCR survey of all 11 Wnt genes in S.
purpuratus reveals that Wnts 5, 8, and ... but not in serotonergic neurons. Using
the FoxQ2 gene as marker of the apical organ and Mox as a
Expression of Wnt genes in lithium and zinc treated embryosFigu...
... Biology and Medical
Modelling
Open Access
Research
A mechanistic model of infection: why duration and intensity of
contacts should be included in models of disease spread
Timo Smieszek
Address: Institute ... participating in the study
contributed diary entries for several days. Finally, contact
patterns are dependent on the cultural background and
may look differently in...
... strategy. Individual cells within microcolonies are genetically related, and
have the ultimate objective of maintaining their own genes and reproducing in the
futur e. To optimize survival of their ... feature of quorum sensing systems. Papers
[33-35] extended the work of early models to study quorum sensing in a growing bio-
film, identifying key physical kinetics parameter...
... to
exuberant inflammation produced by synthetic ePTFE
graft.
Pathogenesis of venous neointimal hyperplasia (VNH)
The most important events initiating the pathogenesis of
VNH are: (a) surgical injury at ... understanding of the cellu-
lar events leading to VNH formation. For simplicity, we
have conglomerated all cytokines and cell types into one
category, giving equal importance to all...
... 5-10-methenyltetrahydrofolate; CH2-THF:
5-10-methylenetetrahydrofolate; Cys: cysteine Cysta cys-
tathionine; DHF: dihydrofolate; DMG: dimethylglycine;
dTMP: deoxythymidine monophosphate; dUMP: deoxyu-
ridine ... combines cysteine and glutamate, is catalyzed by γ-
glutamylcysteine synthetase (GCS); the second step,
which adds the glycine residue, is catalyzed by glutathione
synthetase (GS)....
... TLR4 and injury responsive (TIR) genes pathway analysis. To determine the putative biological role of the TIR genes, the
expression data were analyzed through the use of Ingenuity Pathway Analysis. ... parallel gene expression patterns
observed in patients with initial non-infectious injury. In
this preliminary analysis, we identified a group of 445
genes that exhibited...
... epinephrine, norepinephrine,
dopamine and serotonin. Epinephrine and norepinephrine
function as excitatory hormones. Serotonin functions as
an inhibitory hormone, and dopamine is excitatory in
some ... norepinephrine before and after sym-pathectomy (lasting only 1 minute or so), showing supersensi-tization of the vasculature to norepinephrineFigure 18
Effect of sympathectomy on...