... whiteleg shrimp.
Findings
Origin of IMNV
Infectious myonecrosis virus (IMNV) is a double-
stranded RNA (dsRNA) virus in the family Totiviridae
near the genus Giardiavirus.Diseaseoutbreaksinthe
whiteleg ... 10:10
http://www.jnrbm.com/content/10/1/10
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RESEARC H Open Access
False rumours of disease outbreaks caused by
infectious myonecrosis...
... determined.
Product inhibition studies
The nature and magnitude of the inhibition by the product
galactose 1-phosphate was determined by observing the
effect of increasing concentrations of the ... group
of GHMP kinases in which proton transfer does not play a
major role in the rate determining step of catalysis.
That five of the 10 disease- causing mutations...
... analysis of disease- causing mutations
The steady-state kinetic parameters of each of the nine
disease- causing mutant proteins were determined
(Table 1). In general, little change was seen in K
m
(no
change ... EcoRI at the 3¢
end) and to encode a hexa-histidine tag at the N terminus
of the expressed protein. PCR products were cut with these
enzymes and inserted into...
... determine the prevalence of or absence of
PTB in the national cattle population. These in-
clude the desire to maintain the high health
standards in the national herd, the identification
of infected ... dividing the number of
infected herds detected in each iteration by the
number of infected herds tested in that iteration.
Number of false positive rea...
... a
dimerization domain from an unrelated protein with
no effect on the HSE-binding properties of the protein,
which suggests that yHSF HR-A ⁄ B does not play an
important role in the binding of HSEs, other ... from
heat shock-induced hHSF1 in interactions with the
human c-crystallin promoters. These results show that
the configuration of nGAAn units in the promoter is
im...
... shape of the response curve is
strongly affected by the two groups of parameters that
determine the protein–protein interactions: the concen-
trations of the enzymes relative to the target protein,
and ... dephosphorylation by the kinase) due to competi-
tion of the two enzymes for the target. Indeed, there is
experimental evidence for kinases and phosphatases
co...
... isomerization of peptide bonds
N-terminal of the proline residues [3]. For many proteins,
the cis-trans isomerization of peptide bonds N-terminal
of the proline residues is the rate-limiting step in their
folding ... min prior to the
addition of chymotrypsin. The reaction was initiated by the
addition of 30 lL of 0.76 m
M
chymotrypsin. In the presence
of...
... consider the other sites; a complete
description of the enzyme should take into account the
increase of nucleotide occupancy induced by IF1 [43,44]).
The statements are the following:
The ADP-loaded ... terminal
parts of curves b and c).
In the experiment shown in Fig. 1 curve d, inhibition by
IF1 was studied using SMP in the presence of malonate,
which fully...
... (> 100 mV) in the redox
potential of the heme, with the ÔsuitabilityÕ of the substrate
for catalytic transformation being reflected in the magnitude
of the increase in potential. Thermodynamic ... to
the electrode surface. The further development of the
electrode response, lowering of the reductase peak vs.
increase of the heme peak, indicates that th...
... in the vicinity of 56%.
The potential interaction site on PIP is predicted
by searching for proline residues that mark the ¯anks
of protein±protein interaction sites
The amino-acid sequence of ... effects it possessed,
outlines the potential therapeutic usefulness of t his inhibitor
as an anti -in ammatory agent.
The domain of sPLA
2
or PLI involved in inhibitor
bi...