... riskantidepressants and, 292 – 294 early intervention, rationale for, 290 overview of, 288– 290 , 299 –300pharmacological interventions and, 294 – 298 psychosocial interventions and, 298 – 299 stimulants and, 290 – 292 Positive ... 288–2 89 Bipolar depressioncharacteristics of, 3 09 310definition of, 308 treatment of, 321–326 Bipolar I disorder phenotypes,definitions of, 13–15 Bipolar offspring, 288, 2 89, 294 Bleeding times, ... relevant,research and, 398 – 399 Informed consent, 399 –400Inositol metabolism, 28Institutional review board, 396 Insulin resistance, 3 39, 342–343, 353Involuntary treatment, 394 IQ, 158, 225KKindling, 167–168,...