Diagnosis and Management of Pituitary Disorders - part 1 potx

... Science UniversityBeaverton, ORISBN: 97 8 -1 -5 882 9-7 9 4-5 e-ISBN: 97 8 -1 -6 032 7-0 4 3-4 Library of Congress Control Number: 20089235 01 ©2008 Humana Press, a part of Springer Science+Business Media, LLCAll ... prevalence of 14 .3% ( 31) . A series of 3 surveys conducted in the Indian Ocean island of Mauritius has shown the prevalence of diabetes to have risen from 12 .8% in 19 87 to 15 .2% in 19 92, and 17 .9% in 19 98 ... in Egypt: Risk factors and prevalence.Diabetic Medicine 19 95; 12 : 11 26 11 31. 18 . Arab M. Epidemiology of diabetes mellitus in Egypt. Egyptian J Diabetes 19 97; 2: 1 15 . 19 . Castell C, Tresserras...

Diagnosis and Management of Pituitary Disorders - part 4 potx

... OAD OAD OADA1c% 7.0 7.0 7.2 7.5 7.4 6.9 6.8 6.6(<0.0003) (<0. 01) FPG mg/dL 11 7 12 0 11 5 13 3 11 7 12 7 12 4 11 9(<0.00 01) Hypoglycemia 3.0 5 .1 4 .1 9.9 0.7 3.4 - - events/patient-yr (<0.003) ... 2.5, 5, 10 Y 0.66 1. 5 1. 8 Cglimepiride 1, 2, 3, 4, 6, 8 Y 0.47 (4 mg) 1. 0 – 2.0 Cnateglinide 60, 12 0 N 1. 36 0.5 – 1. 0 Crepaglinide 0.5, 1, 2 N 1. 27 0.5 – 1. 0 Cacarbose 25, 50, 10 0 N 1. 01 0.8 ... MacrovascularMetformin 1A 1B 1B 1BPioglitazone 1A NA 2B 2ARosiglitazone 1A NA NA NAPPAR  &  1B NA NA NASulfonylureas 1A 1B 2B 2BMeglitinides 1A 2B 2B NAAcarbose 1A 2B 2B 2BExenatide 1A NA NA NASitagliptin...

Diagnosis and Management of Pituitary Disorders - part 9 potx

... insulin-like growth factor -1 (IGF -1 ) may also be effectivein lowering glucose and HbA1c levels in CGL patients ( 81) .DIABETES OWING TO GENETIC DISORDERS OF -CELL FUNCTIONMaturity-Onset Diabetes of ... defect HNF-4 GCK HNF -1 (TCF1)IPF -1 HNF -1 (TCF2)NEURO-D1Gene locus 20q 7p 12 q 13 q 17 q 2q32ProteinfunctionOrphan nuclearreceptor,TranscriptionfactorGlucosephospho-rylationenzymeTranscriptionfactorTranscriptionfactorTranscriptionfactorTranscriptionfactorPrimary ... population-basedstudy. Diabetes Care 19 96 ;19 :10 97 11 02. 17 . Kessler RC, McGonagle KA, Zhao S, et al. Lifetime and 12 -month prevalence of DSM-III-R psychiatric disorders in the UnitedStates. Results...

Diagnosis and Management of Pituitary Disorders - part 10 potx

... Results of double-blind, placebo-controlled trial. Diabetes Care 19 95 ;18 :11 33 11 39.35. Ismail K, Winkley K, Rabe-Hesketh S. Systematic Review and meta-analysis of randomized controlled trials of ... profile and lipoprotein(a) in diabetes. Metabolism 2002; 51: 112 0 11 27. 11 1. Grundy SM, Vega GL, McGovern ME, et al. Efficacy, safety, and tolerability of once-daily niacin for the treatment of ... 2002;25 :11 59 11 71. 28. Roter DL, Hall JA, Merisca R, Nordstrom B, Cretin D, Svarstad B. Effectiveness of interventions to improve patient compliance: Ameta-analysis. Med Care 19 98;36 :11 38 11 61. 29....

Diagnosis and Management of Pituitary Disorders - part 2 docx

... and diabetes. J Clin Invest 2005 ;11 5 :11 11 11 19.28. Yuan M, Konstantopoulos N, Lee J, et al. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of ... effects of insulin on hepatic glucose productionin humans. Diabetes 19 97;46 :11 11 11 19. 10 . Lam TK, Schwartz GJ, Rossetti L. Hypothalamic sensing of fatty acids. Nat Neurosci 2005;8:579–584. 11 . Badman ... >24, FPG9 5 -1 25, 2h 14 0 -1 992.8 FPG> ;12 6, 2h> 200 standard lifestyle+ placebo28.9standard lifestyle+ metformin 21. 7 14 intensive lifestyle 14 .4 7Sartor et al. Men with IGT 10 3h OGTT...

Diagnosis and Management of Pituitary Disorders - part 3 docx

... cereal 1/ 3 cupMilk Desserts and Sweets• Fat free, 1% , 2%, whole milk -1 cup • Regular ice cream -1 / 2 cup• Plain yogurt -1 cup • Regular cookie -1 oz.• Jam, jelly or syrup -1 Tbsp.Nonnutritive Sweeteners: ... DPP IV, an enzyme that cleaves GLP -1 , prolonging its half-life. In a recent study (10 1),279 patients with T2DM went through a 4-wk run-in placebo phase and a 12 -wk active treatment phase inwhich ... Care 2002;25 :14 8 19 8. 61. Foster-Powell H, Holt SH, Brand-Miller JC. International table of glycemic index and glycemic load values: 2002. Am J Clin Nutr2002;76:5–56.62. Brand-Miller J, Hayne...

Diagnosis and Management of Pituitary Disorders - part 5 docx

... Chen M-K, Wen Y-S, Chang C-C, Lee H-S, Huang M-T, Hsiao H-C. Deep neck infections in diabetic patients. Am J Otolaryngol2000; 21( 3) :16 9. 11 2. Huang T-T, Tseng F-Y, Liu T-C, Hsu C-J, Chen Y-S. Deep ... Care 19 93 ;16 :11 31 11 36. 31. Haymond MW, Schreiner B. Mini-dose glucagon rescue for hypoglycemia in children with type 1 diabetes. Diabetes Care 20 01; 24:643–645. 19 0 EdelmanTable 5Levels of evidence ... Arthritis Rheum 19 95;38 (12 ) :18 19–25. 17 1. Durand ML, Calderwood SB, Weber DJ, et al. Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med 19 93;328 (1) : 21 8. 17 2. Huang CR,...

Diagnosis and Management of Pituitary Disorders - part 6 pps

... 6 13 %PharmacologicNiacin ER** 1, 500 mg 21% 8–9%Niacin ER 2,000 mg 26% 11 12 %Niacin ER/lovastatin 2,000/40 30– 41% 14 %Gemfibrozil 600 mg BID 6 13 % –Fenofibrate 13 4–200 mg 11 15 % –Pioglitazone 45 mg 15 % –Statins ... GuidelinesADA (15 ) AACE (16 18 ) ACP (19 ,20, 21) JNC 7 (22) NCEP (23)A1C (%) <70∗≤65 <7 (as low as reasonablyfeasible)Fasting Glucose(mg/dL)70 13 0 < ;11 0Post-prandialGlucose (mg/dL)< ;18 0 ... 20 pounds 5 10 % –Increased dietary fat 10 –20% of calories 4–7% –Running* 20 miles per wk 10 15 % –Smoking cessation Stop 1. 5 packs/d 10 % –Ethanol 1. 3 oz (2.5 drinks) 10 –20% 6 13 %PharmacologicNiacin...

Diagnosis and Management of Pituitary Disorders - part 7 docx

... Post Hoc 14 ,703 1 Yr Mortality 10 .9% 16 .2%h HR 1. 50 [1. 21, 1. 85]RCT Analysis 3980 (27 .1) 17 .7%i HR 1. 43 [1. 29, 1. 59]SAVE CHF Post Hoc 22 31 3.5 Yr Mortality 20 .1% 31. 3% OR1.39 [1. 14, 1. 68]RCT ... 7 .1% 11 .6% OR 1. 71, 95% CI [1. 60, 1. 83]NATAMI STEMI Pooled RCT 1, 0 71 In Hospital Mortality 6% 11 % p <0.02Analysis 14 8 (13 .8)GRACE ACS Prospective 15 ,000 In Hospital Mortality 6.4%e 11 .7%e ... RR 1. 48, 95% CI [1. 03, 2 .13 ]Registry NA5 .1% f 6.3%f RR 1. 14, 95% CI [0.85. 1. 52]2.9%g 3.9%g RR 1. 41, 95% CI [1. 02, 1. 95]OASIS ACS Prospective 8, 013 2 Yr Mortality 10 % 18 % RR 1. 57, 95% CI [1. 38,...

Diagnosis and Management of Pituitary Disorders - part 8 ppt

... Arch Surg 2003 ;13 8 :12 40 12 44. 17 . Teli MR, James OF, Burt AD, Bennett MK, Day CP. A natural history of nonalcoholic fatty liver: A follow-up study. Hepatology 19 95;22 :17 14 17 19. 18 . El-Serag HB. ... 2005 ;11 : 19 1 19 8.29. Tsukamoto H, Lu SC. Current concepts in the pathogenesis of alcoholic liver injury. FASEB J 20 01; 15 :13 35 13 49.30. Garg A. Lipodystrophies. Am J Med 2000 ;10 8 :14 3 15 2. 31. ... (10 ,11 ), hypertension (12 ), dyslipidemia (13 17 ), metabolic syndrome (16 ,17 ), and possibly nonalcoholicfatty liver disease (18 ,19 ) and cardiovascular disease (20–29). Effective management of...

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