...
reddish brown,
and often
whitish pink,
and the border
of lesion is at
least in part
a
During much of thi
s time, the precursor stage, lentigo maligna, is confined
to the epidermis.
Source: ...
Lentigo
maligna
melanoma
Sun-
exposed
surfaces,
70 5–20
a
or
longer
In flat
portions, shades
of brown and tan
particularly
malar region
of cheek and
temple
p...
... origin of primary melanoma and because of the large and varied
surface of the nevus. Prophylactic excision early in life can be accomplished by
staged removal with coverage by split-thickness skin ... papillomatous surface.
The border is sharp, and lesions may be oriented along lines of skin cleavage.
Follicular hyper- and hypopigmentation may coexist in a salt -a...
... on the lower
lip. Sun-exposed
skin such as the head, neck, hands, and arms are other typical
sites of involvement. C.
Actinic keratoses consists of hyperkeratotic erythematous
papules and ... sun-exposed skin. They arise in middle-
aged to older
adults and have some potential for malignant transformation. D.
Metastatic
carcinoma to the skin is characterized by infl...
... blacks, and East Asians have rates 10–20 times lower than lighter-
skinned whites. In keeping with the role of sun exposure, the incidence is
inversely correlated with the latitude of residence; ... Cancer of the Skin
Melanoma
Pigmented lesions are among the most common findings on skin
examination. The challenge is to distinguish cutaneous melanomas, which may be...
... areas; the
back is the most common site,
but dysplastic nevi may also be
seen on the scalp, breast
s, and
buttocks
Generally on the sun-
exposed surfaces of the skin
above the waist; the scalp, ... lymph nodes and palpation of the abdominal
viscera are part of the staging examination for suspected melanoma. The patient
should be advised to have other...
... cells and
minimize possible local recurrence. The appropriate width of the margin is a
source of controversy. A World Health Organization trial that prospectively
randomized between 1- and 3-cm ... feasible (such as the
face, hands, or feet), an incisional biopsy through the most nodular or darkest area
of the lesion is acceptable; this should include the vertical...
... behavior of the tumor. These include the size,
location, and degree of histologic differentiation of the tumor as well as the age
and physical condition of the patient. Surgical excision, MMS, and ... modalities with higher cure rates and lower
morbidity. In patients with a history of skin cancer, long-term follow-up for the
detection of recurrence, metast...
... Jr et al: The histogenesis and biologic behavior of primary
human malignant melanoma of the skin. Cancer Res 29 :70 5, 1969 [PMID:
577 3814]
Friedman RI et al (eds): Cancer of the Skin. Philadelphia, ... in the
1990s: The continued importance
of early detection and the role of physician examination and self-
examination of
the skin. CA Cancer J Clin 1:20...
... outside of the area of the prostate bed and is unlikely to be
controlled with radiation therapy.
disease. The practice evolved from studies of predominantly elderly men with
well-differentiated ...
evidence of disease on scan. For these patients the central issue is whether the rise
in PSA results from persistent disease in the primary site, systemic disease, or...
...
mortality in 20 US cities, 198 7- 1 994. The New England Journal of Medicine 343:
174 2-1 74 9.
Emission and Formation of Fine Particles from
Hardcopy Devices: the Cause of Indoor Air Pollution
123 ... night, there were significant decrease in the
particulate numbers and mass concentrations from the working hours of the machine
during the day. While durin...