Báo cáo y học: "Class-switched B cells display response to therapeutic B-cell depletion in rheumatoid arthritis" docx

Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt

Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt

... 2009 BioMed Central Ltd BNIP = BCL2/adenovirus E 1B 19 kDa-interacting protein; C-TAD = carboxyl-terminal transactivating domain; FIH = factor inhibiting HIF; HIF = hypoxia-inducible factor; HRE ... of inflammatory cytokines. The HIF transcription factor family may thus represent an important convergence point in RA, integrating cellular responses to low oxygen tension and to inflammat...
Ngày tải lên : 09/08/2014, 01:22
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Báo cáo y học: "Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis" pdf

Báo cáo y học: "Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis" pdf

... arthritis being initiated by complement-fixing autoantibodies that bind to CII in the cartilage matrix [2]. In humans, IgG-pro- ducing B cells specific for CII are present in rheumatoid synovium and synovial ... an antibody level of 3 or more. CB10 and CB11 antibody detection by ELISA Antibodies against the purified CB peptides of bovine type II collagen, namely CB10 and CB11, w...
Ngày tải lên : 09/08/2014, 01:23
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Báo cáo y học: "Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis" pptx

Báo cáo y học: "Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis" pptx

... major proinflammatory cytokines in RA joints and stimulate IL-6 production by synovial fibroblasts [33- 37], whereas IL-6 is a major circulating cytokine in RA that induces the acute phase response, ... remarkable efficacy of B- cell depletion in rheumatoid factor positive RA with rituximab [43] indicates that B cells are key contributors to the immunopathogenesis of RA. In...
Ngày tải lên : 09/08/2014, 06:22
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Báo cáo y học: "Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis" pptx

Báo cáo y học: "Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis" pptx

... anti-citrullinated peptide antibodies should therefore also be determined. The interac- tion between HLA-DRB1 genotypes and any new RA gene established by association and linkage, such as PTPN22 Table ... Pierlot C, Lasbleiz S, Bardin T, Prum B, Cornélis F: Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22–620 W all...
Ngày tải lên : 09/08/2014, 08:22
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Báo cáo y học: "Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis" pptx

Báo cáo y học: "Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis" pptx

... were obtained between October 2005 and February 2006 from patients visiting the rheumatic outpatient clinic (Clinical Department of Internal Medicine) of the Innsbruck Medical University (Innsbruck, ... RA is based on the cri- teria proposed by the American College of Rheumatology (ACR) in 1987 consisting of clinical symptoms and radiologi- cal findings, whereas the only laboratory test inc...
Ngày tải lên : 09/08/2014, 08:22
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Báo cáo y học: " Characterisation of the immune response to type I collagen in scleroderma" pps

Báo cáo y học: " Characterisation of the immune response to type I collagen in scleroderma" pps

... 13-acetate)/ionomycin activated T cells. (a) We detected interferon (IFN)-γ staining but no interleukin (IL)-4 staining. Mul- tiplex cytokine assay was used to analyse the cytokine profile of three T-cell line ... by intracellular staining/flow cytometry and by multiplex cytokine bead assay (Bio-Plex). A T-cell proliferative response to CI was detected in 8 of 25 (32%) SSc patients,...
Ngày tải lên : 09/08/2014, 08:22
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Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" pps

Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" pps

... GS, Gibson SB, El- Gabalawy HS: Regulation of apoptosis in fibroblast-like syn- oviocytes by the hypoxia-induced Bcl-2 family member Bcl-2/adenovirus E 1B 19-kd protein-interacting protein 3. Arthritis ... of inflammatory cytokines. The HIF transcription factor family may thus represent an important convergence point in RA, integrating cellular responses to low oxygen tension and to...
Ngày tải lên : 09/08/2014, 13:22
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Báo cáo y học: "Infliximab concentration monitoring improves the control of disease activity in rheumatoid arthritis" doc

Báo cáo y học: "Infliximab concentration monitoring improves the control of disease activity in rheumatoid arthritis" doc

... purposes) infliximab in ankylosing spondylitis [18] and inflammatory bowel disease [19], but the determining factor in the concen- tration-effect relation of infliximab is infliximab itself. Only one ... ATI may have underestimated the infliximab determina- tion by neutralizing both infliximab paratopes. However, such undetectable infliximab molecules are inactive and cannot be taken into...
Ngày tải lên : 12/08/2014, 11:22
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Báo cáo y học: "TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies" pot

Báo cáo y học: "TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies" pot

... Questionnaire in a trial comparing hydroxychloroquine vs. sulphasalazine. Scand J Rheumatol 1990, 19:407-412. 15. Shepherd J, Blauw GJ, Murphy MB, Cobbe SM, Bollen EL, Buckley BM, Ford I, Jukema JW, Hyland ... Study Group. PROspective Study of Pravastatin in the Elderly at Risk. Am J Cardiol 1999, 84:1192-1197. 16. Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I,...
Ngày tải lên : 12/08/2014, 11:23
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báo cáo khoa học: "Bidirectional selection for olfactory response to acetaldehyde and ethanol in Drosophila melanogaster" docx

báo cáo khoa học: "Bidirectional selection for olfactory response to acetaldehyde and ethanol in Drosophila melanogaster" docx

... appeared to respond mainly by walking upwind. Hence this olfactometer probably measures mostly mechanical anemotactic reponses (see K ENNEDY , 1977 a). Wind shear forces in the ... ethanol lines, and this may obscure any role of the ADH locus in olfactory variation. An increase in the frequency of ADH-F has been reported in other laborator...
Ngày tải lên : 09/08/2014, 22:23
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