Báo cáo y học: "The S100A8/A9 heterodimer amplifies proinfla

Báo cáo y học: "The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis" potx

... article The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid ... (MAPK) inhibitors and almost completely by nuclear factor kap...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: " 52-kDa Ro/SSA epitopes preferentially recognized by antibodies from mothers of children with neonatal lupus and congenital heart block" pdf

... structure of Ro52, Ro60 and La has been exten- sively studied by several independent groups, and a number of dominant epitopes have been identified in these proteins [20- 22]. However, probably because ... from bovine spleen, which is known to be less effectively recognized by patients' autoan- tibodies than human Ro [25,26]. A second set of data...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo Y học: The membrane-bound [NiFe]-hydrogenase (Ech) from Methanosarcina barkeri : unusual properties of the iron-sulphur clusters docx

... properties of [NiFe]-hydrogenases [27,41]. The interaction of H 2 with hydrogenases offers the possibility to study redox changes in enzyme in the absence of redox mediators simply by varying the H 2 -partial ... conditions, the enzyme catalyses the energetically unfavourable reduction of ferre- doxin by H 2 , most probably driven by energy...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo y học: "The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease" pot

... degradation of ACAN is inhibited by metalloprotease inhibitors, but not by inhibitors of cathepsin B [23]. Others have shown that the addition of retinoic acid to chondrocytes stimulates maturation and ... JR: Inhibition of limb chondrogenesis in vitro by vitamin A. Dev Biol 1978, 64:31-47. 12. Solursh M, Meier S: The selective inhibitio...

Ngày tải lên : 09/08/2014, 01:22

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Báo cáo y học: "The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis" doc

... IM, Maliszewski CR: Anti -cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine- anti -cytokine antibody complexes. J Immunol 1993, ... [7,8], inflammation and cartilage degradation were inhibited by blocking IL-1β but not IL-1α. In RA patients, IL-1β is over- expres...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx

... rformed according to an earlier described recombinant virus assay by determining a virus specific resistance factor [21]. In addition, the Virtual Phenotype™ (based on 53,000 paired genotypes and phenotypes) ... ance against all PIs including ATV and SQV and the majority of NRTIs and NNRTIs resulting in an active drug score (ADS) of ≤ 1.0 for the fail...

Ngày tải lên : 10/08/2014, 05:22

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Báo cáo y học: " “The non-ischemic repair” as a safe alternative method for repair of anterior post-infarction VSD" pptx

... use of systematic hypothermia and any cardioplegic arrest. Furthermore, the total cardio-pulmonary bypass (CPB) time is significantly reduced, tissue debridement and stitching is much easier and ... alternative methods as that of using continuous myocardial pe rfusion after aortic occlusion, or by using intermittent ventricular fibrillation, or by administr...

Ngày tải lên : 10/08/2014, 10:20

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Báo cáo y học: "Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2" pptx

... development of fibrosis. In C57BL/6 mice, bleomycin induces a robust inflammatory response that consists of neutrophils and lymphocytes, with a smaller component of eosinophils [50], in contrast to ... Hospital using standard protocols. The proportion of peribronchial inflammatory cells that were eosinophils was determined by counting inflammatory cel...

Ngày tải lên : 12/08/2014, 18:21

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Báo cáo y học: "Homocysteine-induced macrophage inflammatory protein-2 production by glomerular mesangial cells is mediated by PI3 Kinase and p38 MAPK" doc

... of MAPK and PI-3 Kinase in MIP-2 expression induced by Hcy. Hcy-induced MIP-2 was significantly attenuated (p < 0.05) by a PI-3 Kinase inhibitor (LY294002) and by an inhibitor of a p38MAPK (SB203580). ... abrogated by p38MAPK and PI-3 Kinase inhibitors (A) and by anti-MIP2 antibody (B) Figure 4 Hcy-induced leukocyte cell adhe...

Ngày tải lên : 11/08/2014, 08:22

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Báo cáo y học: "The Systemic Inflammatory Response Syndrome (SIRS) in acutely hospitalised medical patients: a cohort study"

... identified by two or more symptoms including fever or hypothermia, tachycardia, tachypnoea and change in blood leucocyte count. The relationship between SIRS symptoms and morbidity and mortality in medical ... arrival, including clinical examinations as well as radiological evaluation, and where infection was sus- pected by the clinical doctor or indicated by ...

Ngày tải lên : 25/10/2012, 09:56

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