... actively maintained in
the thymus [2]. During this process, a repertoire of T cells
restricted to self-MHC displayed by the thymic cortical
epithelial cells (cTECs) is selected in each individual. In
addition, ... periphery and in the thymus, the immune
system must balance antigen presentation and pro-
inflammatory outcomes in the periphery in response to
pathogens and o...
... inter-
viewer-assisted self-rating scale, rendering it practical for
use in everyday practice. According to the developers,
the instrument can accurately and reliably identify
symptoms of anxiety in older people ... analysis was performed.
Reliability
Internal consistency and reproducibility were measured
as part of the reliability testing of the translated tool
[28]. Internal con...
... basis for the importance of gene
order in the globin locus is not entirely clear, it is in
agreement with the hypothesis that t he genes in the globin
locus are competitively regulated by the LCR ... structure in the globin locus. For example, it
would be interesting to examine t he binding of chromatin
components and transcription factors during the cell cycle in
er...
... c-Jun N-terminal kinase signaling in Stat3 tran-
scriptional activity induced by the Src oncoprotein. Mol
Cell Biol 19, 7519–7528.
19 Yin F, Wang YY, Du JH, Li C, Lu ZZ, Han C &
Zhang YY (2006) ... required
for the production of many cytokines in a wide variety
of cells [21–23].
The gp130
⁄
STAT3 signaling pathway mediated
b-AR-induced ANF expression
b-AR-induced cardiac r...
... cysteine, and
glycine, via two ATP-con suming s teps involving c-g lut-
amylcysteine synthetase ( cGCS) and glutathione synthetase.
The other constitutes a recycling system involving GR
which reduces ... contains no cysteine. Protamine, which is
replaced for hitstone via transit proteins during spermio-
genesis, is rich in both arginine and cysteine. The cysteine
sulfhydryls in protam...
... bridge
with the carboxyl group of the a-aminoadipoyl- side-chain
of penicillin N (1), with arginines 74 and 75 apparently
playing a less important role in side-chain binding. Taken
together, the results ... type of mutant,
represented by arginines 306 and 307, are located in the
C-terminus. They appear to modulate the activity of the
C-terminus, which encloses the DAOCS acti...
... eosin
and hematoxylin staining of the tissue was not inter-
preted as being significant by two independent patholo-
gists. The other eosinophil granules such as ECP [10]
and EDN [ 11] are not ... identify eosinophils in the gastrointestinal tract.
Further research is necessary to identify the triggers for
eosinophilia in L-HES and the application of the novel
monoclonal an...
... only 68 psychiatrists serving a population
of approximately 34 million. Less than half of them are
involved in active clinical work, and they mainly practice
in the major urban areas meaning that ... study
and was involved in drafting the manuscript and revising
it critically for intellectual content. LIK participated in
acquisition, analysis and interpretation of data and was
inv...
... an
important role in this regard. The positive impact of psy-
chotherapy in psychopathy was assessed in a meta-analy-
sis by Salekin et al. [65]. They analysed 42 interventional
studies for individuals ... while observing it being executed by another) was
central in defining theories on neural pathways of empa-
thy [11]. Firstly, this observation was extrapolated to
hypothesise that...