... specificity of this
domain, with residues Tyr91 and Tyr137 forming
interaction pocket 1; Tyr93, Tyr137 and Trp119 form-
ing pocket 2, and the valley between n-Src and RT
loops included by Trp119 and Tyr132 ... grooves 1 and 2 created by the n-Src
loop and the 3
10
helix, stabilized by stacking interac-
tions of the pyrrolidine ring of Pro7 with the aromatic
side...
... study, they were in the CABG
group, if the patient had only had PCI but not CABG, they
were in the PCI group, and if the patient had neither, they
were in the MM group.
Health and Quality of Life ... of CHD severity with sex, the scales of the SAQ and
CCS angina severity class and a smaller relationship with
age and ETT. The variation seen in the relationship...
... author’s name, year of publica-
tion, country of origin, ethnicity, type of asthma,
number of cases and controls, and the minor allele fre-
quency in controls.
Meta-Analysis. The risk of asthma ... severity [29].
Therefore, as one of the C-C chemokines, the
RANTES polymorphisms necessarily resulted into the
level of eosinophils elevating correspond, and th...
...
association. Among the haplotypes of the three
polymorphic sites, the Abf homozygote showed that a
VDR allele positively affected the prevalence of severe
chronic disease. The ff genotype of the FokI ... in the Dental Longitudinal Study in the
United States. Specifically, they reported that the loss
of alveolar bone and clinical attachment occurred at
the...
... diabe-
tes, weight gain and obesity are major side effects of many
antipsychotics [11-13]. Obesity itself leads to hyperten-
sion, type II diabetes and coronary heart disease, many of
the same problems ... in the psychia-
try outpatient clinic of the Aga Khan University Hospital
(AKUH) over a 4-year period. Patients were identified
using the Psychiatric Assessment System (PA...
... border between the hydrolases and transglycosi-
dases, but rather there may be one between the compact
cluster of Bacillus and Thermoanaerobacter CGTases and
the remaining enzymes. The positions of ... N-terminal part of the enzymes to
one influenced more by taxonomy at the C-terminal part of
the same enzymes (Figs 3 and 4) can be seen in the present
study....
... BamH1 and EcoR1 restriction
enzyme sites, and the sequence was mutated to replace
Cys189 with Ser, and thus increasing the stability of the
protein and eliminating the possibility of isoprenylation.
Recombinant ... member of the serine/threonine kinase family,
which includes three types of isoform, PAK68, PAK65 and
PAK62. They have been shown to have a high degree...
...
The frequency of the C -allele was 0.24 and the
genotypes were distributed according to the Hardy
Weinberg Equilibrium. Overall the C allele frequency was
higher in patients with coronary ...
studied 4 PPARδ haplotypes and found that effects on
plasma lipids and coronary lesions were primarily due to
the influence of the +T294C SNP. The C allele frequency...
... described by others [16], the
use of MG132 unexpectedly blocks the formation of
complex-type structures.
Interactions between TSHR and CNX, CRT, and BiP
During and after their synthesis, glycoproteins ... necessary to the folding and
oligomeric assembly of various glycoproteins [17].
To study the role of CNX and CRT in the folding of
newly synthesized TSHR mole...
... preceding
them. All assessments were conducted at the
Physiology Laboratory of the Exercise and Sport
Research Center of the Universidade Federal do
Paraná.
The study protocol was approved by the ...
reported the presence of T2D (yes or no) previously
diagnosed by a physician.
Statistical analyses
The Kolmogorov Smirnov test of normality was
used to determine t...