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... be
achieved by microarray analysis to identify mRNAs that are
translated or remain untranslated under different conditions
in a given cell type. Microarray analyses have already been
valuable in exploring ... trans-
lation across the board of mRNAs that are already actively
being translated.
How could increased phosphorylation of eIF4E actually
inhibit cap-dependent translation, a...
... change agents of the car-
egiver and of family life in general.
Caregivers of children in the Ritalin LA subgroup, children
aged 6-9 years, and girls reported greater improvements
from baseline ... Dublin, Ireland]), an alternative to oral
MPH formulation, is approved by the US Food and Drug
Administration (FDA) as part of a comprehensive treat-
ment for ADHD in childr...
... cancer, and diabetes mel-
litus. The year -by- year findings in Panama and in the
San Blas for those four conditions are shown in Table 3.
The stability year -by- year for each diagnosis in Pa-
nama ... history and physical findings supplemented
by the results of tests, including x-ray, angiography,
ultrasound examination, the electrocardiogram, and
occasionally a bi...
... insulin and other growth factors. All of these
transmembrane receptors contain protein tyrosine kinase
activity in their intracellular domain [1]. The signalling
pathway of insulin is similar ... crosstalks with the typical
growth factor signalling pathway, such as receptor protein
tyrosine kinase/ growth factor receptor binding protein
2-son of sevenless protein/ Ras/Raf/...
... rina
`
ria, Universitat Auto
`
noma de
Barcelona, Bellaterra 08193, Ba rcelona, Spain.
E-mail: Joaquin.Arino@uab.es
Abbreviations: MAP kinase, mitogen activated protein kinase; TOR,
target of rapamycin; ... associates, in a SAP-independent fashion to
Tap42, an essential protein [31] that is phosphorylated by
the target of rapamycin (TOR) kinases [32]. Therefore, Sit4
appears i...
...
et al. for the National Kidney Disease Education Program
Laboratory Working Group Recommendations for Improving
Serum Creatinine Measurement: A Report from the Laboratory
Working Group of ... uncertainty
calculations (40-80 mL/(min x 1.73 m
2
)). Since the
calculated uncertainty corresponds to an
intralaboratory uncertainty it is an underestimate of
the interlaboratory uncertain...
... the
measure of increased enjoyment during eating.
Readiness to eat has been evaluated in different studies by
recording blood glucose dynamics, by examining saliva-
tion and by self-reported hunger ... individuals is related to increased swallowing rate,
as measured by the number of swallows per minute [4].
Bellisle et al showed that increased palatability of food
increases...
... cardiovascular mechanical
stressors such as frequent apneas causing increases in
negative intrathoracic pressure and cardiac pre -and
after-load work; and intermittent hypoxemia via
causing endothelial ... better marker of cardiovas-
cular risk in OSA especially with higher arousal in-
dex.
Arousals are associated with acute surges in
blood pressure and heart rate [5-...
... toxicity and the de novo acquisition of particular
electrophysiological properties) remains unclear. Interest-
ingly, it was recently proposed that the pharmacological
versatility displayed by scorpions ... concentrations were
determined by spectrometry. SDS/PAGE was performed
using the Phast System from Pharmacia.
Bacterial strains and plasmids
The E. coli strain MV1190 was used as...
... the manuscript,
Dr Marc Baumann for N-terminal sequencing and K atja Sissi, Teija
Inkinen and Lea A rmassalo for help with laboratory work. Financial
support was provided by the University of Helsinki, ... disease mutations, H1069Q of WD
ATPase) and P476L have similar c haracteristics. They
retain 37% and 23% of the wild-type A TPase activity,
respectively, and are poorl...