...
µ
m.
Osteopontin in rat spinal cord with EAN 293
nerves and spinal roots. These two molecules may be
involved in cell migration into the spinal cord in the early
stages of EAN. Further study of the functional ... neurons in
the spinal cord express OPN and CD44 in EAN
Immunohistochemistry showed expression of OPN in
some cells in the spinal cord p...
... compromised by the inhibition of
PI3K signaling with LY294002 in a fully supplemented
medium and within the tested time period (Fig. 3B, D).
QDs induce the formation of LDs in PC12 cells
in a growth ... possibility; however, the inhibition
of PI3K with LY294002 and the inhibition of FAS
with cerulenin caused the disappearance of droplets
and prevented the f...
... the point of view
of enthalpy, but unfavored from the point of view of
entropy. A 25 °C, the higher entropy of the linear
form is likely due to its higher flexibility, the higher
mobility of the ... cm
)1
at 25 °C of about the same
integral intensity, indicating a larger population of lin-
ear conformers. The upshift and increase in intensity
of the peak a...
... mutagenesis of the involve-
ment of some of these residues in the docking and catalysis
of cinnamic acid. The impact of the active site mutations on
the binding and metabolism of cinnamic acid ... residue in the initial binding and correct
positioning of CA during catalysis. A role of N302 in
anchoring the side-chain carboxylate of CA is further
supported...
... layers of pearl
oysters, leaving the other shell layers poorly investi-
gated at the molecular level. One exception is the find-
ing of acidic glycoprotein MSP-1 in the foliated layer
of Patinopecten ... green
staining. Arrows on the right side of the lanes indicate the position
of the 52 kDa component. A weakly stained band in lane A does
not correspond to the...
... 0.05).
Consistent with the expected association of transforming growth factor beta-1 (TGF-β1) with late
tissue injury, levels of the cytokine were significantly higher in the skin of the C57BL/6 mouse
compared ... study the effects of radi-
ation in case of scleroderma. Further studies are required
to elucidate the role of FBN-1 in controlling TGF-β1 sign-
al...
... receive RT/BT, 5 recurred in the pelvis (4 in the
vagina, 1 in the lateral pelvis). In contrast, none of the
patients who received RT/BT (total of 10) recurred in the
pelvis. The 5-year pelvic recurrence ... Lately
there has been an increase in the use of IMRT to spare the
blood marrow, providing that, in case of a relapse and
need for new chemotherapy re...
... Therefore,
proteasome inhibition by ROS might be involved in the
increased expression of c-Fos in this experimental sys-
tem. The mechanism(s) underlying the upregulation of
c-Fos should be examined in greater ... DNA
binding (Fig. 3). Pretreatment with SP600125, an
inhibitor of c-Jun N-terminal kinase, showed no effect
on the DNA binding of c-Fos and c-Jun induced...
... lacking the Ca
2+
⁄ CaM-binding
IQ domain, did not increase the basal or serotonin-
induced ERK1 ⁄ 2 phosphorylation. The ERK1 ⁄ 2 phos-
phorylation was inhibited in the presence of the
calcium in ux ... (F340) increases, whereas the
fluorescence intensity at 380 nm (F380) decreases upon
the binding of Ca
2+
. The change in the ratio of
F340 ⁄ F380 determined the...