Báo cáo khoa học: " Effect of fixation time and freeze-thaw cycles on the molecular analysis of viral DNA" ppt

Báo cáo khoa học: "Embryonic Intermediate Filaments, Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis" pdf

Báo cáo khoa học: "Embryonic Intermediate Filaments, Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis" pdf

... EAE lesions [3]. The latter focused on the remyelination capacity of the CNS after an EAE attack. Consequently, we postulate that glial elements along the central canal and subpial regions are ... paralysis, and finally, spontaneous recovery. These steps are matched by an inflammatory response in the CNS, which is cha- racterized by the infiltration of T cells and macr...
Ngày tải lên : 07/08/2014, 17:22
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Báo cáo khoa học: "Improved survival following surgery and radiation therapy for olfactory neuroblastoma: analysis of the SEER database" pdf

Báo cáo khoa học: "Improved survival following surgery and radiation therapy for olfactory neuroblastoma: analysis of the SEER database" pdf

... Though the etiology is unknown[2], ONB appears to arise from the olfactory membrane of the sinonasal tract and prefere ntially involves the anatomic distribution of the epithelium overlying the ... analysis. MEP, TLM, MM, and AKS wrote the manuscript. All authors reviewed the statistical analysis results, contributed to the interpretation of the results and...
Ngày tải lên : 09/08/2014, 09:20
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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... affect the association of the substrate with the enzyme in any one of several ways, e.g. through solvation effects on substrates or enzyme active sites and through their effects on the thermodynamic ... understanding the effect of osmolytes on protein stability, folding and the activity of proteins and enzymes, the relationship between protein stabilization...
Ngày tải lên : 07/03/2014, 00:20
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Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc

Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc

... formation of hydrogen bonds between the nitrogen atoms of the ligands and the backbone oxygen of Pro325. Although we did not directly com- pare the molecular interaction energies of NMTIQ and MPTP ... center of the catalytic site, the latter prompting oxidation of the iron and consequent hTH inactivation. TH inhibition by endogenous TIQs depends critically o...
Ngày tải lên : 07/03/2014, 05:20
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Báo cáo khoa học: X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35fiTyr mutant pdf

Báo cáo khoa học: X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35fiTyr mutant pdf

... any hydrogen bond with the protein atoms. The former propionate displays the conserved conformation in the structures of the Phe35fiTyr mutant and of the wild-type protein as well as other mutants. However, ... chain conformation of this residue. The shift of the Ca atom of Tyr35 of the Phe35fiTyr mutant from that of Phe35 of the wild-type cyt b 5 is 0.21 A...
Ngày tải lên : 08/03/2014, 10:20
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Báo cáo khoa học: A new rice zinc-finger protein binds to the O2S box of the a-amylase gene promoter pptx

Báo cáo khoa học: A new rice zinc-finger protein binds to the O2S box of the a-amylase gene promoter pptx

... of three copies of the O2S domain at the 5¢ end of the CYC1 mini-promoter region. Following transfor- mation of the URA-marked plasmid pLGD-265 UP1 containing the O2S domain and the TRP-marked ... transcription [4,5]. Rogers and Rogers [4] found that both GARE and O2S functioned only when positioned in one orientation with respect to each other and with respect to...
Ngày tải lên : 16/03/2014, 18:20
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Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf

Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf

... phospholipase A2 is in the nucleus of sub- confluent endothelial cells but confined to the cytoplasm of confluent endothelial cells and redistributes to the nuclear envelope and cell junctions upon histamine ... cell. The subcellular locations of these proteins also vary, with some being present in the ER, others in the nuclear membrane and some present at both these loca...
Ngày tải lên : 16/03/2014, 18:20
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Báo cáo khóa học: CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes doc

Báo cáo khóa học: CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes doc

... suggest that the stabilization of CD38 homodimers by crosslinkers depends strongly on the conformation and orientation between the CD38 monomers. It has been reported that NP-40 and Triton X-100 stabilize ... values of each of the clones). The relative enzyme activity of each of the mutants is given in parentheses. It was determined by setting the V max adjusted...
Ngày tải lên : 23/03/2014, 12:20
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Báo cáo hóa học: " Research Article Real-Time Cardiac Arrhythmia Detection Using WOLA Filterbank Analysis of EGM Signals" pot

Báo cáo hóa học: " Research Article Real-Time Cardiac Arrhythmia Detection Using WOLA Filterbank Analysis of EGM Signals" pot

... representing the beat locations. By further analysis of the synchrony of the subband beats and the periodicity and regularity of the optimal beat, various possible cardiac events (in- cluding fibrillation, ... signal, the narrowband (com- plex) subbands are merged to obtain wideband-subband sig- nals to be used for wideband event detection. The results of the wide...
Ngày tải lên : 22/06/2014, 23:20
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