báo cáo hóa học:" Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease" pptx

Báo cáo hóa học: " Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells" ppt

Báo cáo hóa học: " Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells" ppt

... molecules integrins in gastric epithelial cells. In the present stu dy, the role of PAR-2 on H. pylori-induced cell death was investigated by determining cell viability, DNA fragmentation, and the ... none (the cells without treatment and cultured in the absence of H. pylori). + P < 0.05 compared to the corresponding none (the cells without treatment and culture...
Ngày tải lên : 18/06/2014, 16:20
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Báo cáo hóa học: " Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters" potx

Báo cáo hóa học: " Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters" potx

... However, no insertions of A were observed in the any of these non-coding sequences, showing that the high frequency of A inser- tions was predominantly confined to the region encoding the non-essential ... removed and/ or the M2 termination signal was altered by the introduction of the Swa I site. Table 1: Frequency of GFP fluorescence in Vero cells infected with...
Ngày tải lên : 20/06/2014, 01:20
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Báo cáo hóa học: " Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens" doc

Báo cáo hóa học: " Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens" doc

... were obtainable from the very young chicks, limit- ing the scope of their investigation. Another group of chickens was hatched and reared indoors, and serum sam- ples collected at 9 weeks of age. Plaque ... concentrated in the fertile egg and that the quantity of these antibodies declines rapidly in the newly hatched chick [13]. Our PRNT results are totally consi...
Ngày tải lên : 20/06/2014, 01:20
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Báo cáo hóa học: " Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed β-propeller domain of the HIV-1 cellular interactor EED" pptx

Báo cáo hóa học: " Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed β-propeller domain of the HIV-1 cellular interactor EED" pptx

... towards the lower face of the β- propeller (Fig. 3). The absence of overlapping of the MA and IN binding sites and the possible occurrence of ter- nary complex involving EED, MA and IN raised the ... protein. Mapping of the HIV-1 MA and IN binding sites on the 3D-model of EED core predicted that EED-bound MA and IN ligands would be in close vi...
Ngày tải lên : 20/06/2014, 01:20
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Tài liệu Báo cáo khoa học: Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor-1 against inactivating agents pptx

Tài liệu Báo cáo khoa học: Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor-1 against inactivating agents pptx

... family of serine proteinase inhibitors. Serpins inhibit their target proteinases by an ester bond being formed between the active site serine of the proteinase and the P 1 residue of the reactive ... of the covalent bond, the proteinase is translocated to the opposite pole of the serpin [6–8], the active site becoming distorted, the catalytic machinery inactiva...
Ngày tải lên : 20/02/2014, 11:20
  • 8
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Báo cáo khoa học: Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin potx

Báo cáo khoa học: Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin potx

... the C-terminal part of MUC5AC harboring the von Wille- brand C domain and cysteine-knot domain [16]. In the case of 166M1, a very faint band corresponding to the C2-H fragment was detected, indicating ... MUC5AC and that their epitopes are located in the C-terminal cysteine-rich part of this mucin. Results and Discussion The recombinant C-terminal cysteine-rich par...
Ngày tải lên : 07/03/2014, 05:20
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Báo cáo khoa học: Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10–23 potx

Báo cáo khoa học: Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10–23 potx

... deoxyribozyme 10–23 includes the interactions of divalent cations with both the pro- R P and proS P oxygens of P5, and an interaction with the oxygen ligand at C6 of the subsequent guanosine nucleotide ... Mn 2+ ,Zn 2+ ,orCd 2+ ,in increasing order (the rescue effect). Analysis of these types of interaction led to a better understanding of the mechanistic aspe...
Ngày tải lên : 07/03/2014, 10:20
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Báo cáo khoa học: Mapping of the interaction site of CP12 with glyceraldehyde-3-phosphate dehydrogenase from Chlamydomonas reinhardtii Functional consequences for glyceraldehyde-3-phosphate dehydrogenase pot

Báo cáo khoa học: Mapping of the interaction site of CP12 with glyceraldehyde-3-phosphate dehydrogenase from Chlamydomonas reinhardtii Functional consequences for glyceraldehyde-3-phosphate dehydrogenase pot

... the arrow on the left indicates the beginning of the associ- ation phase; the beginning of the dissociation phase is marked by the arrow on the right. Interaction site between GAPDH and CP12 S. ... (analyte). The NaCl concentration was increased from 0.15 m (HBS buffer) to 0.65 m as indicated in the text. The analyte interacts with the ligand (CP12) to give...
Ngày tải lên : 16/03/2014, 13:20
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Báo cáo khoa học: Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis potx

Báo cáo khoa học: Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis potx

... structural insight into the organization of the substrate binding cavity and highlight residues implicated in substrate ⁄ inhibitor binding in the S1¢ site of the enzyme. To complement and extend the ... the vicinity of substrate ⁄ inhib- itor binding pockets. The experimental results, together with the molecular modeling, suggest that the amino acid residues...
Ngày tải lên : 23/03/2014, 07:20
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báo cáo hóa học:" Summary of the primer on tumor immunology and the biological therapy of cancer" ppt

báo cáo hóa học:" Summary of the primer on tumor immunology and the biological therapy of cancer" ppt

... lymphodepleted patients with melanoma in combination with high dose IL-2 has been shown to achieve clinical responses in the range of 50%. However, minimal activity of IL-2 in the treatment of other cancers ... large numbers of high avidity tumor-reactive CD8 + T cells in individual patients in time and maintain their survival in vivo. The solution is ge...
Ngày tải lên : 18/06/2014, 15:20
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