... for 6 and 3 days, respectively, after seeding. Alltransepithelial transport studies were conducted on con-fluent cell monolayers.At the time of commencement of the transportexperiments, the ... LLC-PK1 and HK-2 cell monolayers wasassessed in the presence and absence of the known inhi-bitor of organic cation transport [24,31-33], quinidine(Sigma-Aldrich Canada Ltd., Canada). Cell monolayerswere ... par-tially due to the inhibition of renal tubular secretion of creatinine by acyclovir, and not entirely the result of decreased GFR. To the best of our kno wledge, the effect of acyclovir on the renal...